• Current Clinical Studies

    Ongoing Studies

    Research Study to Learn More about What Causes Lupus
    This is a research study to determine the cause of lupus and to improve understanding of the disease. The study specifically seeks to help find the genes that are involved in lupus development and to learn how they work differently in people with and without the condition. Studying lupus at the genetic level to determine its causes may lead to advances that will improve how it is diagnosed and treated. Contact Nicolette Barbour, clinical research assistant, 513-803-3307,  nicolette.barbour@cchmc.org.

    Children and Teens 8 to 18 Needed for Lupus Outcomes Research Study
    The purpose of this research study is to support the Pediatric Patient Reported Outcomes Measurement Information System (PROMIS) Item Banks for pediatric systematic lupus erythematosus (pSLE) and compare its performance to other quality of life measures previously proven for pSLE. Contact Alexa Greenler, Alexandria.Greenler@cchmc.org, 513-803-4328.

    Lupus Database
    The purpose of this study is to create an electronic database of patients diagnosed with systemic lupus erythematosus (SLE). This database will serve as a resource list of patients to contact for clinical trials of new medicines. People listed in the database will be individually contacted about trials they may be eligible for and then have the choice of whether or not to participate. Data to be collected include name, date of birth, address, phone number, clinical information from medical records and from questionnaires completed by physicians and patients. No blood tests are required. Contact Kasha Wiley, kasha.wiley@cchmc.org, 513-803-2118.

    Puberty Study
    This study addresses the question of how hormonal changes in puberty affect lupus in girls who have been diagnosed with lupus. The study includes visits every 3 months over an approximate three-year period, blood draws and urine samples. Physical examinations are performed and questionnaires completed.  Contact Jamie Eaton, jamie.eaton@cchmc.org, 513-636-0395.

    Current Studies, Closed to Enrollment

    Biomarkers for Systemic Lupus Erythematosus (SLE) Renal Disease
    This study is looking at why the kidneys are more likely to be affected in SLE that starts in childhood than in SLE first diagnosed in adults. Data will be gathered from medical records and questionnaires. No experimental medicines, treatments or procedures are involved, although blood and urine samples are required. Study participants will need to visit the Lupus Clinic 7 times over a period of 18 months. Contact study coordinator Jamie Eaton, jamie.eaton@cchmc.org, 513-636-0395.

    Download the Urinary Biomarkers May Differentiate Between Children with ISN/RPS Class IV versus Class V of Lupus Nephritis (LN) Abstract.

    Download Candidate Urinary Biomarkers May Predict Histological Features On Lupus Nephritis (LN) Biopsy Abstract.