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The Neuromuscular Cardiology team is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our co-directors and staff.
John Lynn Jefferies, MD, MPH, FAAP, FACC Director, Advanced Heart Failure and Cardiomyopathy 513-803-1675 firstname.lastname@example.org
Director, Advanced Heart Failure and Cardiomyopathy
Associate Professor, UC Department of Pediatrics
Dr. Jefferies, an associate professor of pediatric cardiology and adult cardiovascular diseases within the University of Cincinnati College of Medicine, is the director of Advanced Heart Failure / Cardiomyopathy in the Heart Institute at Cincinnati Children's Hospital Medical Center.
He completed his combined pediatric and adult cardiology training at the Baylor College of Medicine in Houston, Texas at the Texas Children's Hospital and the Texas Heart Institute. He has authored or co-authored over 120 peer-reviewed manuscripts and book chapters on cardiomyopathy, cardiovascular genetics, and adults with congenital heart disease.
His current research interests include heritable causes of cardiovascular disease, novel drug therapies for advanced heart failure, novel gene discovery in cardiomyopathy, characterization and management of left ventricular noncompaction (LVNC), and early diagnosis and management of chemotherapy induced cardiotoxicity.
He is on the editorial board of the Texas Heart Institute Journal and is an active member of numerous professional organizations, including the Heart Failure Society of America, the American College of Cardiology and the American Heart Association. He is the lead editor for two textbooks that focus on the management of heart disease in children and young adults entitled “Heart Failure in the Child and Young Adult: From Bench to Bedside” and “Cardioskeletal Myopathies in Children and Young Adults.”
BS: University of Tennessee, Knoxville, TN, 1992.
MD: University of Tennessee, Knoxville, TN, 1996.
Residency: University of Kentucky, Lexington, KY, 2000.
MPH: University of Kentucky, Lexington, KY, 2001 Fellowship: Baylor College of Medicine, Houston, TX, 2006.
Certification: Pediatrics, Internal Medicine, Cardiology, Advanced Heart Failure, Cardiac Transplant.
Towbin JA, Lorts A, Jefferies JL. Left ventricular noncompaction cardiomyopathy. Lancet. 2015;Apr 9. Epub ahead of print.
McCullough PA, Jefferies JL. Novel Markers And Therapies For Patients With Acute Heart Failure And Renal Dysfunction. Am J Med. 2015 Mar;128(3):312.e1-22.
Villa CR, Ryan TD, Collins JJ, Taylor MD, Lucky AW, Jefferies JL. Left ventricular non-compaction cardiomyopathy associated with epidermolysis bullosa simplex with muscular dystrophy and PLEC1 mutation. Neuromuscul Disord. 2015 Feb;25(2):165-8.
Raman SV, Hor KN, Halnon NJ, Kissel JT, He X, Tran T, Smart S, McCarthy B, Taylor MD, Jefferies JL, Rafael-Fortney JA, Lowe J, Roble SL, Cripe LH. Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2015 Feb;14(2):153-61.
Jefferies JL. Barth syndrome. Am J Med Genet C Semin Med Genet. 2013 Aug;163C(3):198-205.
Breinholt JP, Moulik M, Dreyer WJ, Denfield SW, Kim JJ, Jefferies JL, Rossano JW, Gates CM, Clunie SK, Bowles KR, Kearney DL, Bowles NE, Towbin JA. Viral epidemiologic shift in inflammatory heart disease: the increasing involvement of parvovirus B19 in the myocardium of pediatric cardiac transplant patients. J Heart Lung Transplant. 2010 Jul;29(7):739-46.
Carlson P, Jefferies JL, Kearney D, Russell H. Refractory dilated cardiomyopathy associated with metastatic neuroblastoma. Pediatr Blood Cancer. 2010 Jun 29.
Shah AM, Jefferies JL, Rossano JW, Decker JA, Cannon BC, Kim JJ. Electrocardiographic abnormalities and arrhythmias are strongly associated with the development of cardiomyopathy in muscular dystrophy. Heart Rhythm. 2010 Jun 18.
Rossano JW, Morales DL, Zafar F, Denfield SW, Kim JJ, Jefferies JL, Dreyer WJ. Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transplant patients: An analysis of the United Network for Organ Sharing database. J Thorac Cardiovasc Surg. 2010 May 26.
Brenda Wong, MD, MBBS Director, Comprehensive Neuromuscular Center/MDA Clinic 513-636-4222 email@example.com
Director, Comprehensive Neuromuscular Center/MDA Clinic
Professor, UC Department of Pediatrics
UC Department of Neurology
After medical school, Brenda Wong, MD, received training in general pediatrics and worked as a pediatrician for a few years before doing her three-year child neurology fellowship at Cincinnati Children's Hospital Medical Center.
Dr. Wong also received training in pediatric neuromuscular disorders at Hammersmith Hospital, London with Dr. Victor Dubowitz and Dr. Francesco Muntoni. Dr. Wong's training in EMGs was accomplished with Dr. John Quinlan in the Department of Neurology at University of Cincinnati.
Post fellowship training, Dr. Wong was practicing child neurology in private practice prior to joining Cincinnati Children's in 1999.
Besides general neurology patients, Dr. Wong sees patients with neuromuscular disorders in the Neuromuscular Clinic and provide diagnostic services like EMGs and evaluation for muscle biopsies. Comprehensive management is supported by the Division of Rehabilitative Medicine, Pulmonary Medicine, Pediatric Orthopedics and the Muscular Dystrophy Association.
MD: University of Singapore, 1980.
Residency: University Department of Pediatrics, Singapore, 1981, 1984-85; Royal Hospital for Sick Children, Edinburgh, 1985-88.
Fellowship: Child Neurology, Children's Hospital Medical Center, Cincinnati, OH, 1994-97; Neuromuscular Disorders, Hammersmith Hospital, London, 1997.
Certification: Child Neurology, 1998.
Miles MV, Putnam PE, Miles L, Tang PH, DeGrauw AJ, Wong BL, Horn PS, Foote HL, Rothenberg ME. Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies. Mitochondrion. 2011 Jan;11(1):127-35.
Kim HK, Laor T, Horn PS, Racadio JM, Wong B, Dardzinski BJ. T2 mapping in Duchenne muscular dystrophy: distribution of disease activity and correlation with clinical assessments. Radiology. 2010 Jun;255(3):899-908.
Kim HK, Laor T, Horn PS, Wong B. Quantitative assessment of the T2 relaxation time of the gluteus muscles in children with Duchenne muscular dystrophy: a comparative study before and after steroid treatment. Korean J Radiol. 2010 May-Jun;11(3):304-11.
Yang Z, Funke BH, Cripe LH, Vick GW 3rd, Mancini-Dinardo D, Peña LS, Kanter RJ, Wong B, Westerfield BH, Varela JJ, Fan Y, Towbin JA, Vatta M. LAMP2 microdeletions in patients with Danon disease Circ Cardiovasc Genet. 2010 Apr;3(2):129-37.
Henderson RC, Berglund LM, May R, Zemel BS, Grossberg RI, Johnson J, Plotkin H, Stevenson RD, Szalay E, Wong B, Kecskemethy HH, Harcke HT. The relationship between fractures and DXA measures of BMD in the distal femur of children and adolescents with cerebral palsy or muscular dystrophy. J Bone Miner Res. 2010 Mar; 25(3):520-6.
Erin M. Miller, MS, CGC Genetic Counselor, Cardiology Clinic 513-636-4729 firstname.lastname@example.org
Genetic Counselor, Cardiology Clinic
MS: Medical Genetics, Indiana Univeristy, Indianapolis, IN, 2005.
BS: Psychology, The University of Arizona, Tucson, AZ, 2003.
Certification: American Board of Genetic Counseling, 2007.
Ashley S. Parrott, MS
Genetic Counselor II, Heart Institute 513-803-3318 email@example.com
Amy R. Shikany, MS
Genetic Counselor, Heart Institute 513-803-3317 firstname.lastname@example.org
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