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Division Head

John B. Harley, MD, PhD
Director, Rheumatology

513-803-3665

john.harley@cchmc.org

High Res

John B. Harley, MD, PhD

Director, Rheumatology

Professor, UC Department of Pediatrics

Phone: 513-803-3665

Email: john.harley@cchmc.org

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Publications

View PubMed Publications

Cobb BL, Fei Y, Jonsson R, Bolstad AI, Brun JG, Rischmueller M, Lester SE, Witte T, Illei G, Brennan M, Bowman S, Moser KL, Harley JB, Sawalha AH. Genetic association between methyl-CpG binding protein 2 (MECP2) and primary Sjögren’s syndrome. Ann Rheum Dis. 2010; 69(9): 1731-2.

Kim-Howard X, Maiti AK, Anaya J-M, Bruner GR, Brown E, Merrill JT, Edberg JC, Petri MA, Reveille JD, Ramsey-Goldman R, Alarcon GS, Vyse TJ, Gilkeson G, Kimberly RP, James JA, Guthridge JM, Harley JB, Nath SK. ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash, and immunologic manifestations in lupus patients with European ancestry . Ann Rheum Dis. 2010.

Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, Rodriguez-Ubreva J, Berdasco M, Fraga MF, O'Hanlon TP, Rider LG, Jacinto FV, Lopez-Longo FJ, Dopazo J, Forn M, Peinado MA, Carreno L, Sawalha AH, Harley JB, Siebert R, Esteller M, Miller FW, Ballestar E. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res. 2010; 20(2):170-179.

Harley JB, James JA. Everyone comes from somewhere: systemic lupus erythematosus and epstein-barr virus, induction of host interferon (INF) and humoral anti-EBNA1 immunity. Arthritis Rheum. 2010.

\Bronson PG, Komorowski LK, Ramsay PP, May SL, Noble J, Lane JA, Thomson G, Claas FH, Seldin MF, Kelly JA, Harley JB, Moser KL, Gaffney PM, Behrens T, Criswell LA, Barcellos LF. Analysis of maternal-offspring HLA compatibility, parent-of-origin and noninherited effects for HLA-DRB1 in systemic lupus erythematosus . Arthritis Rheum. 2010.

Heinlen LD, McClain MT, Ritterhouse LL, Bruner BF, Edgerton CC, Keith MP, James JA, Harley JB. 60kD Ro and nRNP A frequently initiate human lupus autoimmunity. PLoS ONE. 2010 5(3):e9599.

Sammalisto S, Hiekkalinna T, Schwander K, Kardia S, Weder AB, Rodriquez BL, Doria A, Kelly JA, Bruner GR, Harley JB, Redline S, Larkin EK, Patel SR, Ewan AJ, Weber JL, Perola M, Peltonen L.Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex-and population-specific genetic effects. Eur J Hum Genet. 2009 Jan 1;17(2):258-266.

Poole BD, Templeton AK, Guthridge JM, Brown EJ, Harley JB, James JA. Aberrant Epstein-Barr viral infection in systemic lupus erythematosus. Autoimmun Rev. 2009 Feb;8(4):337-42.

Poole BD, Schneider RI, Guthridge JM, Velte CA, Reichlin M, Harley JB, James JA. Early targets of nuclear RNP humoral autoimmunity in human systemic lupus erythematosus. Arthritis Rheum. 2009 Feb 26; 60(3):848-859.

Han S, Kim-Howard X, Deshmukh H, Kamatani Y, Viswanathan P, Guthridge JM, Thomas K, Kaufman KM, Ojwang J, Rojas-Villarraga A, Baca V, Orozco L, Rhodes B, Choi CB, Gregersen PK, Merrill JT, James JA, Gaffney PM, Moser KL, Jacob CO, Kimberly RP, Harley JB, Bae SC, Anaya JM, Alarcon-Riquelme ME, Matsuda K, Vyse TJ, Nath SK. Evaluation of imputation-based association in and around the Integrin-α-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE). Hum Mol Genet. 2009 Mar 15;18(6):1171-80.

Grants

Molecular & Immunologic Analysis of the Pathobiology of Human Anthrax. Co-Principal Investigator. National Institute of Allergy and Infectious Diseases. Sep 2009 - Aug 2014. #AI062629-06.

Genomics of Lupus. Principal Investigator. Aug 2009 - Jul 2014. #1 P01 AI083194-01.

Oklahoma Autoimmunity Center of Excellence Project 2. Co-investigator. National Institute of Allergy and Infectious Diseases. May 2009 - Apr 2014. #1 U19 AI082714-01.

Genome-Wide Association Study in African-Americans with Systemic Lupus Erythematosus. Principal Investigator. Department of Defense. Sep 2010- Aug 2013. #PR094002.

Genomics of Lupus Associations in the Hispanic 12q24 Linkage. Principal Investigator. National Institutes of Health. Jun 2008 - Mar 2013. #5 P01 AR049084-07.

Lupus Association with Signal Transducer and Activator of Transcription 4. Principal Investigator. US Department of Veterans Affairs. Apr 2008 - Mar 2012.

Genetic Linkage in Lupus. Principal Investigator. National Institute of Allergy and Infectious Diseases. Feb 2010 - Jan 2012. #3 R37 AI024717-21S1.

Faculty

Hermine I. Brunner, MD, MSc

513-636-4676

hermine.brunner@cchmc.org

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Hermine I. Brunner, MD, MSc

Professor, UC Department of Pediatrics

Phone: 513-636-4676

Fax: 513-636-4116

Email: hermine.brunner@cchmc.org

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Specialties

Clinical Interests

Health-related quality of life; outcome research; lupus

Research Interests

Economic analyes; HRQOL; measurement development; outcome research; lupus

Visit the Brunner Lab.

Biography

Hermine Brunner, MD, MSc, is a pediatric rheumatologist with a special clinical and research interest in pediatric lupus. Her research is focused on biomarker discovery and the testing of new medications for lupus. She is also involved in trial design and provides statistical support at Cincinnati Children's. As head of the Lupus Center, she is involved in the conduction of the Lupus Clinic and the organization of Lupus Support Groups. She also pioneers the development of outcome measures and improving the quality of clinical of children with lupus and other rheumatic diseases.

Education and Training

MD: Ludwig Maximilan University, Munich, Germany, 1991.

Residency: University of Chicago, 1997.

Fellowship: University of Toronto & Cincinnati, 1999.

MSc: Clinical Epidemiology: University of Toronto, 1999.

Certification: Pediatrics 1997; Rheumatology 2002.

Publications

View PubMed Publications

Sherwin CM, Fukuda T, Brunner HI, Goebel J, Vinks AA. The evolution of population pharmacokinetic models to describe the enterohepatic recycling of mycophenolic Acid in solid organ transplantation and autoimmune disease. Clin Pharmacokinet. 2011 Jan 1;50(1):1-24.

Sagcal-Gironella AC, Fukuda T, Wiers K, Cox S, Nelson S, Dina B, Sherwin CM, Klein-Gitelman MS, Vinks AA, Brunner HI. Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid and Their Relation to Response to Therapy of Childhood-Onset Systemic Lupus Erythematosus. Semin Arthritis Rheum. 2010 Jul 22.

Brunner HI, Higgins GC, Klein-Gitelman MS, Lapidus SK, Olson JC, Onel K, Punaro M, Ying J, Giannini EH. Minimal clinically important differences of disease activity indices in childhood-onset systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Jul;62(7):950-9.

Brunner HI, Klein-Gitelman MS, Higgins GC, Lapidus SK, Levy DM, Eberhard A, Singer N, Olson JC, Onel K, Punaro M, Schanberg L, von Scheven E, Ying J, Giannini EH. Toward the development of criteria for global flares in juvenile systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Jun;62(6):811-20.

Brunner HI, Higgins GC, Wiers K, Lapidus SK, Olson JC, Onel K, Punaro M, Ying J, Klein-Gitelman MS, Giannini EH. Prospective validation of the provisional criteria for the evaluation of response to therapy in childhood-onset systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Mar;62(3):335-44.

Mina R, Brunner HI. Pediatric lupus--are there differences in presentation, genetics, response to therapy, and damage accrual compared with adult lupus?Rheum Dis Clin North Am. 2010 Feb;36(1):53-80, vii-viii.

Ford KR, Myer GD, Melson PG, Darnell SC, Brunner HI, Hewett TE. Land-Jump Performance in Patients with Juvenile Idiopathic Arthritis (JIA): A Comparison to Matched Controls. Int J Rheumatol. 2009;2009:478526. Epub 2010 Jan 27.

Kocharla L, Taylor J, Weiler T, Ting TV, Luggen M, Brunner HI. Monitoring methotrexate toxicity in juvenile idiopathic arthritis. J Rheumatol. 2009 Dec;36(12):2813-8. Epub 2009 Nov 16.

Brunner HI, Ravelli A. Developing outcome measures for paediatric rheumatic diseases. Best Pract Res Clin Rheumatol. 2009 Oct;23(5):609-24. Review.

Hinze CH, Suzuki M, Klein-Gitelman M, Passo MH, Olson J, Singer NG, Haines KA, Onel K, O'Neil K, Silverman ED, Tucker L, Ying J, Devarajan P, Brunner HI. Neutrophil gelatinase-associated lipocalin is a predictor of the course of global and renal childhood-onset systemic lupus erythematosus disease activity. Arthritis Rheum. 2009 Sep;60(9):2772-81.

Edward H. Giannini, MSc, DrPH

513-636-7634

edward.giannini@cchmc.org

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Edward H. Giannini, MSc, DrPH

Professor, UC Department of Pediatrics

Phone: 513-636-7634

Email: edward.giannini@cchmc.org

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Publications

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Lovell DJ, Passo MH, Beukelman T, Bowyer SL, Gottlieb BS, Henrickson M, Ilowite NT, Kimura Y, DeWitt EM, Segerman J, Stein LD, Taylor J, Vehe RK, Giannini EH. Measuring process of arthritis care: a proposed set of quality measures for the process of care in juvenile idiopathic arthritis. Arthritis Care Res (Hoboken). 2011 Jan;63(1):10-6. doi: 10.1002/acr.20348.

Giannini EH, Ilowite NT, Lovell DJ, Wallace CA, Rabinovich CE, Reiff A, Higgins G, Gottlieb B, Chon Y, Zhang N, Baumgartner SW. Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis. Arthritis Rheum. 2010 Nov;62(11):3259-64. doi: 10.1002/art.27682.

Brunner HI, Higgins GC, Klein-Gitelman MS, Lapidus SK, Olson JC, Onel K, Punaro M, Ying J, Giannini EH. Minimal clinically important differences of disease activity indices in childhood-onset systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Jul;62(7):950-9.

Brunner HI, Klein-Gitelman MS, Higgins GC, Lapidus SK, Levy DM, Eberhard A, Singer N, Olson JC, Onel K, Punaro M, Schanberg L, von Scheven E, Ying J, Giannini EH. Toward the development of criteria for global flares in juvenile systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Jun;62(6):811-20.

Brunner HI, Higgins GC, Wiers K, Lapidus SK, Olson JC, Onel K, Punaro M, Ying J, Klein-Gitelman MS, Giannini EH. Prospective validation of the provisional criteria for the evaluation of response to therapy in childhood-onset systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Mar;62(3):335-44.

Giannini EH, Mehta AB, Hilz MJ, Beck M, Bichet DG, Brady RO, West M, Germain DP, Wanner C, Waldek S, Clarke JT, Mengel E, Strotmann JM, Warnock DG, Linhart A. A validated disease severity scoring system for Fabry disease. Mol Genet Metab. 2010 Mar;99(3):283-90.

Giannini EH, Ilowite NT, Lovell DJ, Wallace CA, Rabinovich CE, Reiff A, Higgins G, Gottlieb B, Singer NG, Chon Y, Lin SL, Baumgartner SW; Pediatric Rheumatology Collaborative Study Group. Long-term safety and effectiveness of etanercept in children with selected categories of juvenile idiopathic arthritis. Arthritis Rheum. 2009 Sep;60(9):2794-804.

Carrasco R, Lovell DJ, Giannini EH, Henderson CJ, Huang B, Kramer S, Ranz J, Heubi J, Glass D. Biochemical markers of bone turnover associated with calcium supplementation in children with juvenile rheumatoid arthritis: results of a double-blind, placebo-controlled intervention trial. Arthritis Rheum. 2008 Dec;58(12):3932-40.

Lovell DJ, Ruperto N, Goodman S, Reiff A, Jung L, Jarosova K, Nemcova D, Mouy R, Sandborg C, Bohnsack J, Elewaut D, Foeldvari I, Gerloni V, Rovensky J, Minden K, Vehe RK, Weiner LW, Horneff G, Huppertz HI, Olson NY, Medich JR, Carcereri-De-Prati R, McIlraith MJ, Giannini EH, Martini A; Pediatric Rheumatology Collaborative Study Group; Pediatric Rheumatology International Trials Organisation. Adalimumab with or without methotrexate in juvenile rheumatoid arthritis. N Engl J Med. 2008 Aug 21;359(8):810-20.

Lovell DJ, Reiff A, Ilowite NT, Wallace CA, Chon Y, Lin SL, Baumgartner SW, Giannini EH; Pediatric Rheumatology Collaborative Study Group. Safety and efficacy of up to eight years of continuous etanercept therapy in patients with juvenile rheumatoid arthritis. Arthritis Rheum. 2008 May;58(5):1496-504.

David N. Glass, MD
Professor of Pediatrics

513-636-7686

david.glass@cchmc.org

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David N. Glass, MD

Professor of Pediatrics

Professor, UC Department of Pediatrics

Phone: 513-636-7686

Fax: 513-636-4116

Email: david.glass@cchmc.org

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Specialties

Immunogenetics of rheumatic disease in children.

Visit the Glass-Thompson Lab.

Education and Training

MD: University of Birmingham, England, 1965.

Residency: Internal Medicine, Charing Cross Hospital, London, England.

Fellowship: Rheumatology, Kennedy Institute of Rheumatology, London, England; Charing Cross Hospital, London, England; Robert B. Brigham Hospital, Harvard Medical School, Boston, MA.

Certification: Internal Medicine, Royal College of Physicians, London, England, 1968.

Publications

View PubMed Publications

Thompson SD, Sudman M, Ramos PS, Marion MC, Ryan M, Tsoras M, Weiler T, Wagner M, Keddache M, Haas JP, Mueller C, Prahalad S, Bohnsack J, Wise CA, Punaro M, Zhang D, Rosé CD, Comeau ME, Divers J, Glass DN, Langefeld CD. The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1. Arthritis Rheum. 2010 Nov;62(11):3265-76. doi: 10.1002/art.27688.

Barnes MG, Grom AA, Thompson SD, Griffin TA, Luyrink LK, Colbert RA, Glass DN. Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis. Arthritis Rheum. 2010 Nov;62(11):3249-58. doi: 10.1002/art.27657.

Thompson SD, Barnes MG, Griffin TA, Grom AA, Glass DN. Heterogeneity in juvenile idiopathic arthritis: impact of molecular profiling based on DNA polymorphism and gene expression patterns. Arthritis Rheum. 2010 Sep;62(9):2611-5. No abstract available.

Barnes MG, Grom AA, Thompson SD, Griffin TA, Pavlidis P, Itert L, Fall N, Sowders DP, Hinze CH, Aronow BJ, Luyrink LK, Srivastava S, Ilowite NT, Gottlieb BS, Olson JC, Sherry DD, Glass DN, Colbert RA. Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis. Arthritis Rheum. 2009 Jul;60(7):2102-12.

Griffin TA, Barnes MG, Ilowite NT, Olson JC, Sherry DD, Gottlieb BS, Aronow BJ, Pavlidis P, Hinze CH, Thornton S, Thompson SD, Grom AA, Colbert RA, Glass DN. Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. Arthritis Rheum. 2009 Jul;60(7):2113-23.

Zhang K, Biroschak J, Glass DN, Thompson SD, Finkel T, Passo MH, Binstadt BA, Filipovich A, Grom AA. Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms. Arthritis Rheum. 2008 Sep;58(9):2892-6.

Fall N, Barnes M, Thornton S, Luyrink L, Olson J, Ilowite NT, Gottlieb BS, Griffin T, Sherry DD, Thompson S, Glass DN, Colbert RA, Grom AA. Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum. 2007 Nov;56(11):3793-804.

Chaudhari M, Moroldo MB, Shear E, Hillard P, Thompson SD, Lan D, Huang B, Brunner HI, Glass DN. Impaired reproductive fitness in mothers of children with juvenile autoimmune arthropathies. Rheumatology (Oxford). 2006 Oct;45(10):1282-7.

Phelan JD, Thompson SD, Glass DN. Susceptibility to JRA/JIA: complementing general autoimmune and arthritis traits. Genes Immun. 2006 Jan;7(1):1-10. Review.

Alexei A. Grom, MD

513-636-3339

alexei.grom@cchmc.org

High Res

Alexei A. Grom, MD

Associate Professor, UC Department of Pediatrics

Phone: 513-636-3339

Fax: 513-636-3328

Email: alexei.grom@cchmc.org

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Specialties

Visit the Grom-Thorton Lab.

Biography

The research of Alexei Grom, MD, has mainly involved two translational projects focused on two autoimmune diseases – systemic juvenile rheumatoid arthritis and juvenile dermatomyositis. In both projects, recent advances of cellular immunology are applied to these diseases to promote better understanding of their pathogenesis and treatment.

Systemic Onset Juvenile Rheumatoid Arthritis and an associated condition known as Macrophage Activation Syndrome are severe and often devastating illnesses. The pathological mechanisms are not known but Dr. Alexei Grom has focused his research on NK and cytotoxic cell function in this disease. The rationale for this approach has been based on the strong clinical similarities between MAS and the better understood autosomal recessive disorder familial hemophagocytic lymphohistiocytosis, in which the uncontrolled proliferation of T cells and macrophages has been recently associated with decreased NK cell and cytotoxic cell functions secondary to mutations in the gene encoding perforin. Recent observations suggest as in FHLH, MAS patients also have profoundly depressed NK function. Moreover, a large subgroup of systemic JRA patients has very similar immunologic abnormalities. Combined with the evidence of the immunoregulatory role of NK cells in many immune responses, this suggests that NK dysfunction is relevant to the pathogenesis of MAS. New directions have thus been established for research in this poorly understood disease.

Juvenile Dermatomyositis is a chronic inflammatory condition involving primarily muscles and skin. The most characteristic feature of JDM is vascular damage associated with the capillary necrosis that eventually leads to capillary loss and tissue ischemia. The project is based on the hypothesis that capillary loss in this condition may be caused by angiostatic chemokines that are prominent in the inflammatory response in the affected muscles.

Education and Training

MD: Leningrad (St. Petersburg) Pediatric Medical Institute, Russia, 1986.

Residency: Leningrad (St. Petersburg) Medical Institute, Russia, 1988; Children's Hospital Medical Center, Cincinnati, Ohio, 1998.

Fellowship: Leningrad (St. Petersburg) Pediatric Medical Institute, Russia, 1991; Children's Hospital Medical Center, Cincinnati, Ohio, 1995.

Certification: Pediatrics, 1999.

Publications

View PubMed Publications

Grom AA, Mellins ED. Macrophage activation syndrome: advances towards understanding pathogenesis. Curr Opin Rheumatol. 2010 Sep;22(5):561-6. Review.

Filipovich A, McClain K, Grom A. Histiocytic disorders: recent insights into pathophysiology and practical guidelines. Biol Blood Marrow Transplant. 2010 Jan;16(1 Suppl):S82-9.

Shishov M, Henrickson M, Burgos-Vargas R, Rubio-Pérez N, Baca V, Romero-Feregrino R, Solís-Vallejo E, Huang B, Grom AA, Lovell DJ. Systemic features and early prognostic factors in Hispanic and non-Hispanic children from the United States of America and Mexico with systemic juvenile idiopathic arthritis. Clin Exp Rheumatol. 2007 Nov-Dec;25(6):907-14.

Michael Henrickson, MD, MPH
Clinical Director

513-636-7686

michael.henrickson@cchmc.org

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Michael Henrickson, MD, MPH

Clinical Director

Associate Professor, UC Department of Pediatrics

Phone: 513-636-7686

Email: michael.henrickson@cchmc.org

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Specialties

Health policy; global health; neuropsychiatric-SLE; periodic fever syndromes; systemic JIA; culturally appropriate care; quality measures

Education and Training

BA: Emory University, Atlanta, GA, 1980.

MD: Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, 1984.

MPH: College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2009.

Residency: Tripler Army Medical Center, Honolulu, HI, 1984-87.

Fellowship: Children’s Hospital Medical Center, Cincinnati, OH, 1991-94.

Certification: American Board of Pediatrics: General Pediatrics, 1988 (recertified 2004). Pediatric Rheumatology, 1994 (recertified 2008). National Board of Public Health Examiners, 2009.

Publications

View PubMed Publications

Henrickson M, Reid J, Bellet JS, Sawchuk SS, Hirsch R. Comparison of in vivo efficacy and mechanism of action of antimurine monoclonal antibodies directed against TCR alpha beta (H57-597) and CD3 (145-2C11). Transplantation. 1995 Oct 27;60(8):828-35.

Henrickson M, Giannini EH, Hirsch R. Reduction of mortality and lymphadenopathy in MRL-lpr/lpr mice treated with nonmitogenic anti-CD3 monoclonal antibody. Arthritis Rheum. 1994 Apr;37(4):587-94.

Jennifer L. Huggins, MD
Fellowship Program Director, Rheumatology

513-803-0649

jennifer.huggins@cchmc.org

Jennifer L. Huggins, MD

Fellowship Program Director, Rheumatology

Assistant Professor, UC Department of Pediatrics

Phone: 513-803-0649

Email: jennifer.huggins@cchmc.org

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Education and Training

MD: University of Kansas Medical School, Kansas City, Kansas

Publications

View PubMed Publications

Huggins JL, Coca A, Bundy, KW, Marston B, Looney RJ. Macrophage Activation Syndrome: Serological Markers and Treatment with Anti-Thymocyte Globulin. Clinical Immunology. 2009 132(1):10-18.

Huggins JL, Sanz I et al. Cellular Origin of Autoantibodies in Systemic Lupus Erythematosus. A&R. 2007 56:S1427.

Huggins JL, Sanz I, Zand M et al. CpG DNA Activation and Plasma Cell Differentiation of CD27- Naïve Human B Cells. Blood. 2007109:1611-1619.

Huggins, JL, Brunner HI. Targeting B Cell in the Treatment of Childhood-Onset Systemic Lupus Erythematosus. Journal of Pediatrics 2006;148:571-3.

Zand M, Sanz I, Huggins J et al. Apoptosis and complement-mediated lysis of myeloma cells by polyclonal rabbit antithymocyte globulin. Blood. 2006 107:2895-2903.

Huggins JL, Sanz I, Zand M et al. Differential Requirements of Naïve Peripheral Blood B Cells for Activation by CpG DNA. Annals of Rheumatic Diseases. 2006.

Looney RL, Huggins JL. Use of Intravenous Immunoglobulin G (IVIG). Bailliere’s Best Practice in Clinical Haematology. 2006 19:3-27.

Zand, M, Vo T, Huggins J, et al. Polyclonal Rabbit Antithymocyte Globulin Triggers B-Cell and Plasma Cell Apoptosis by Multiple Pathways. Transplantation. 2005 79:1507-1515.

Huggins JL, Sanz I, Zand M. CpG DNA Induces Plasma Cell Differentiation of Naïve CD27- Human B Cells. A&R. 2004 50:S227.

Huggins JL, Sanz I, Zand M. CpG DNA Induces Plasma Cell Differentiation of Naïve CD27- Human B Cells. Clinical and Investigative Medicine. 2004 27.

Daniel J. Lovell, MD, MPH
Associate Director, Division of Rheumatology

513-636-4676

daniel.lovell@cchmc.org

High Res

Daniel J. Lovell, MD, MPH

Associate Director, Division of Rheumatology

Professor, UC Department of Pediatrics

Phone: 513-636-4676

Fax: 513-636-5990

Email: daniel.lovell@cchmc.org

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Specialties

Clinical Interests

Diagnostic evaluation and ongoing care of children with all pediatric onset rheumatic diseases

Research Interests

Performance of clinical trials in children with rheumatic diseases; clinical trials methodology; mentoring of junior faculty

Education and Training

MD: University of Kansas, Kansas City, Kan., 1978.

MPH: University of Texas School of Public Health, Houston, Texas, 1982.

Residency: Children's Mercy Hospital, Kansas City, Kan.

Fellowship: Baylor College of Medicine, Houston, Texas.

Certification: Pediatrics, 1984; Pediatric Rheumatology, 1992.

Publications

View PubMed Publications

Seid M, Opipari L, Huang B, Brunner HI, Lovell DJ. Disease control and health-related quality of life in juvenile idiopathic arthritis. Arthritis Rheum. 2009 Mar 15;61(3):393-9.

Ting TV, Lovell DJ. Does early sulfasalazine treatment provide long-term benefits to patients with juvenile idiopathic arthritis?Nat Clin Pract Rheumatol. 2008 Jul;4(7):344-5.

Lovell DJ. Update on treatment of arthritis in children: new treatments, new goals.Bull NYU Hosp Jt Dis. 2006;64(1-2):72-6. Review.

Esi Morgan DeWitt, MD, MSCE

513-636-4676

esi.morgan-dewitt@cchmc.org

High Res

Esi Morgan DeWitt, MD, MSCE

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-4676

Email: esi.morgan-dewitt@cchmc.org

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Specialties

Clinical Interests

Childhood rheumatic diseases; juvenile idiopathic arthritis; juvenile dermatomyositis; sarcoidosis

Research Interests

Patient reported outcomes measure development; quality Improvement; health services research; economic evaluationsl; comparative effectiveness

Biography

Esi Morgan DeWitt, MD, MSCE is a pediatric rheumatologist and researcher. Clinical care spans the childhood rheumatic diseases, with focus on juvenile idiopathic arthritis (JIA) and juvenile dermatomyositis.

Her research training and experience includes epidemiology and health services research, in addition to specialization in quality improvement methods and application to improve health care delivery. Dr. Morgan DeWitt leads a research project to develop new measures to assess pain in children and youth, as well as to validate measures of health related quality of life in children with juvenile idiopathic arthritis or chronic pain as part of a national network of investigators.

Dr. Morgan DeWitt is a leader in a multi-center quality improvement network to improve the outcome of care in children with JIA, the Pediatric-Rheumatology Care and Outcomes Improvement Network. Additionally, she has served on expert panels in development of JIA treatment recommendations and measures of quality of care in treatment of JIA.

Education and Training

MD: Washington University School of Medicine, St. Louis, MO, 1999.

Residency: Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA, 2002.

Fellowship: Rheumatology, Children’s Hospital of Philadelphia, Philadelphia, PA, 2005.

MSCE: University of Pennsylvania, Center for Clinical Epidemiology & Biostatistics, Philadelphia, PA, 2005.

Certification: Pediatrics, 2002; Pediatric Rheumatology, 2006.

Publications

View PubMed Publications

Dewitt EM, Stucky BD, Thissen D, Irwin DE, Langer M, Varni JW, Lai JS, Yeatts KB, Dewalt DA. Construction of the eight-item patient-reported outcomes measurement information system pediatric physical function scales: built using item response theory. J Clin Epidemiol. 2011 Jul;64(7):794-804.

Beukelman T, Patkar NM, Saag KG, Tolleson-Rinehart S, Cron RQ, DeWitt EM, et al. American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res. 2011 Apr;63(4):465-82.

Dinan MA, Compton KL, Dhillon JK, Hammill BG, Dewitt EM, Weinfurt KP, Schulman KA. Use of patient-reported outcomes in randomized, double-blind, placebo-controlled clinical trials. Med Care. 2011 Apr;49(4):415-9.

Varni JW, Stucky BD, Thissen D, Dewitt EM, Irwin DE, Lai JS, Yeatts K, Dewalt DA. PROMIS Pediatric Pain Interference Scale: An item response theory analysis of the Pediatric Pain Item Bank. J Pain. 2010 Nov;11(11):1109-19.

Irwin DE, Stucky BD, Thissen D, Dewitt EM, Lai JS, Yeatts K, Varni JW, DeWalt DA. Sampling plan and patient characteristics of the PROMIS pediatrics large – scale survey. Qual Life Res. 2010 May;19(4):585-94.

DeWitt EM, Lin L, Glick HA, Anstrom KJ, Schulman KA, Reed SD. Pattern and predictors of the initiation of biologic agents for the treatment of rheumatoid arthritis in the United States: an analysis using a large observational data bank. Clin Ther. 2009 Aug; 31(8):1871-80; discussion 1858.

Morgan DeWitt E, Glick HA, Albert DA, Joffe M, Wolfe F. Medicare coverage of tumor necrosis factor α inhibitors as an influence on physicians’ prescribing behavior. Arch of Intern Med. 2006;166:57-63.

Book Chapters

DeWitt EM, Schanberg LE, Rabinovich CE. Treatment of Rheumatic Diseases. In RM Kleigman, BM Stanton, J St.Geme, N Schor, RE Behrman (Eds.), Nelson Textbook of Pediatrics. 19th ed. Elsevier Saunders: Philadelphia, PA, 2011.

Wu EY, DeWitt, EM. Sarcoidosis. In RM Kleigman, BM Stanton, J St.Geme, N Schor, RE Behrman (Eds.), Nelson Textbook of Pediatrics.19th ed. Elsevier Saunders: Philadelphia, PA, 2011.

Grants

Juvenile Arthritis Improvement Network. Principal Investigator. Arthritis Foundation. July 2010 - Jun 2012.

Leveraging Epic for Quality Improvement in Rheumatology. Co-Principal Investigator.Place Outcomes Research Award, Cincinnati Children's Hospital Medical Center. Jul 2010 - Jun 2012.

Enhancing PROMIS in Pediatric Pain, Rheumatology and Rehabilitation Research. Principal Investigator. National Institutes of Health. Sep 2009 - Jul 2013. #1U01AR057940-01.

Susan Thompson, PhD

513-636-3899

susan.thompson@cchmc.org

Susan Thompson, PhD

Associate Professor, UC Department of Pediatrics

Phone: 513-636-3899

Email: susan.thompson@cchmc.org

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Specialties

Molecular basis of juvenile rheumatoid arthritis; large-scale integrative analysis of gene expression, polymorphism and other genomic data with clinical data

Visit the Glass-Thompson Lab.

Biography

Susan Thompson, PhD, has research interests that span both genetic and functional genomic studies of juvenile rheumatoid arthritis (JRA) to advance the understanding of the causes and mechanisms of disease pathogenesis. A genome-wide screen for JRA susceptibility traits has been completed and defined several regions for linkage mapping and candidate gene analysis. In addition, complementary approaches that measure global gene expression patterns using DNA microarrays are also being used to understand the molecular basis for disease.

Education and Training

PhD: University of Tennessee Center for Health Sciences, Memphis, TN, 1988.

Fellowship: Immunology, St. Jude Children's Research Hospital, Memphis, TN, 1988-1991.

Fellowship: Molecular Genetics, University of Cincinnati, Cincinnati, OH, 1991-1994.

Publications

View PubMed Publications

Chaudhari M, Moroldo MB, Shear E, Hillard P, Thompson SD, Lan D, Huang B, Brunner HI, Glass DN. Impaired reproductive fitness in mothers of children with juvenile autoimmune arthropathies. Rheumatology (Oxford). 2006 Oct;45(10):1282-7.

Phelan JD, Thompson SD. Genomic progress in pediatric arthritis: recent work and future goals. Curr Opin Rheumatol. 2006 Sep;18(5):482-9.

Phelan JD, Thompson SD, Glass DN. Susceptibility to JRA/JIA: complementing general autoimmune and arthritis traits. Genes Immun. 2006 Jan;7(1):1-10.

Sherry L. Thornton, PhD

513-636-1318

sherry.thornton@cchmc.org

High Res

Sherry L. Thornton, PhD

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-1318

Fax: 513-636-3328

Email: sherry.thornton@cchmc.org

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Specialties

Evaluating targets for the treatment of rheumatic disease; angiogenesis; animal models of arthritis

Visit the Grom-Thornton Lab.

Education and Training

BS: Ball State University, Muncie, Indiana.

PhD: University of Cincinnati, College of Medicine, Cincinnati, OH.

Postdoctoral Research Fellow: Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Publications

View PubMed Publications

Hinze CH, Fall N, Thornton S, Mo JQ, Aronow BJ, Layh-Schmitt G, Griffin TA, Thompson SD, Colbert RA, Glass DN, Barnes MG, Grom AA. Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis. Arthritis Res Ther. 2010;12(3):R123.

Griffin TA, Barnes MG, Ilowite NT, Olson JC, Sherry DD, Gottlieb BS, Aronow BJ, Pavlidis P, Hinze CH, Thornton S, Thompson SD, Grom AA, Colbert RA, Glass DN. Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. Arthritis Rheum. 2009 Jul;60(7):2113-23.

Fall N, Barnes M, Thornton S, Luyrink L, Olson J, Ilowite NT, Gottlieb BS, Griffin T, Sherry DD, Thompson S, Glass DN, Colbert RA, Grom AA. Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum. 2007 Nov;56(11):3793-804.

Flick MJ, LaJeunesse CM, Talmage KE, Witte DP, Palumbo JS, Pinkerton MD, Thornton S, Degen JL. Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif. J Clin Invest. 2007 Nov;117(11):3224-35.

Fall N, Bove KE, Stringer K, Lovell DJ, Brunner HI, Weiss J, Higgins GC, Bowyer SL, Graham TB, Thornton S, Grom AA. Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with juvenile dermatomyositis: possible link to vasculopathy. Arthritis Rheum. 2005 Oct;52(10):3175-80.

Carey B, DeLay M, Strasser JE, Chalk C, Dudley-McClain K, Milligan GN, Brunner HI, Thornton S, Hirsch R. A soluble divalent class I MHC/IgG1 fusion protein activates CD8+ T cells in vivo. Clin Immunol. 2005 Jul;116(1):65-76.

Huang P, Farkas T, Zhong W, Tan M, Thornton S, Morrow AL, Jiang X. Norovirus and histo-blood group antigens: demonstration of a wide spectrum of strain specificities and classification of two major binding groups among multiple binding patterns. J Virol. 2005 Jun;79(11):6714-22.

Hermann LM, Pinkerton M, Jennings K, Yang L, Grom A, Sowders D, Kersten S, Witte DP, Hirsch R, Thornton S. Angiopoietin-like-4 is a potential angiogenic mediator in arthritis. Clin Immunol. 2005 Apr;115(1):93-101.

Katakura S, Jennings K, Watanabe S, Adachi E, Thornton S, Gao GP, Wilson JM, Burstein H, Trapnell B, Hirsch R. Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy. Mod Rheumatol. 2004;14(1):18-24.

Tracy V. Ting, MD

513-636-4676

High Res

Tracy V. Ting, MD

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-4676

Fax: 513-636-5568

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Education and Training

MD: West Virginia University, Morgantown, WV, 2002.

Residency: Cleveland Clinic, Cleveland, OH, 2005.

Certification: Pediatrics, 2005.

Publications

View PubMed Publications

Kashikar-Zuck S, Parkins IS, Ting TV, Verkamp E, Lynch-Jordan A, Passo M, Graham TB. Controlled follow-up study of physical and psychosocial functioning of adolescents with juvenile primary fibromyalgia syndrome. Rheumatology (Oxford). 2010 Nov;49(11):2204-9.

Kashikar-Zuck S, Flowers SR, Verkamp E, Ting TV, Lynch-Jordan AM, Graham TB, Passo M, Schikler KN, Hashkes PJ, Spalding S, Banez G, Richards MM, Powers SW, Arnold LM, Lovell D. Actigraphy-based physical activity monitoring in adolescents with juvenile primary fibromyalgia syndrome. J Pain. 2010 Sep;11(9):885-93.

Kashikar-Zuck S, Johnston M, Ting TV, Graham BT, Lynch-Jordan AM, Verkamp E, Passo M, Schikler KN, Hashkes PJ, Spalding S, Banez G, Richards MM, Powers SW, Arnold LM, Lovell D. Relationship between school absenteeism and depressive symptoms among adolescents with juvenile fibromyalgia. J Pediatr Psychol. 2010 Oct;35(9):996-1004.

Kocharla L, Taylor J, Weiler T, Ting TV, Luggen M, Brunner HI. Monitoring methotrexate toxicity in juvenile idiopathic arthritis. J Rheumatol. 2009 Dec;36(12):2813-8.

Ting TV, Lovell DJ. Does early sulfasalazine treatment provide long-term benefits to patients with juvenile idiopathic arthritis? Nat Clin Pract Rheumatol. 2008 Jul;4(7):344-5.

Ting TV, Scalzi LV, Hashkes PJ. Nonclassic neurologic features in cryopyrin-associated periodic syndromes. Pediatr Neurol. 2007 May;36(5):338-41.

Administrative

Tomiko A. Crocker
Administrative Assistant, Division of Rheumatology

513-636-0009

tomiko.crocker@cchmc.org

Thomas A. Dow
Financial Analyst I, Division of Rheumatology

513-636-5334

thomas.dow@cchmc.org

Elaine A. Holtkamp
Administrative Assistant, Division of Rheumatology

513-636-7467

elaine.holtkamp@cchmc.org

John A. Kerechek, MAS
Business Director, Division of Rheumatology, Center for Autoimmune Genomics and Etiology (CAGE)

513-803-0614

john.kerechek@cchmc.org

Amanda LaGreca-Schaefer
Administrative Assistant

513-803-2672

amanda.lagreca_schaefer@cchmc.org

Gabriel Miller
Financial Specialist, Rheumatology

513-636-2143

gabriel.miller@cchmc.org

Susan Priest
Administrative Supervisor, Division of Rheumatology

513-636-6320

susan.priest@cchmc.org

Jill Segerman, MEd
Education Specialist, Rheumatology

513-636-6266

jill.segerman@cchmc.org

Ebony Washington
Administrative Assistant, Rheumatology

513-636-8029

ebony.washington@cchmc.org

Clinical

Kara L. Brown, PCA
Patient Care Assistant, Division of Rheumatology and Lupus Center

513-636-4676

Mary Beth Burns, RN
Care Manager, Rheumatology Outpatient Center and Lupus Center

513-636-4676

mary-beth.burns@cchmc.org

Elaine F. Haddix, RN, CPN
Registered Nurse, Rheumatology Outpatient Center

513-636-9801

Pamela A. Heydt, LISW
Social Worker, Division of Rheumatology

513-636-5568

pam.heydt@cchmc.org

Shalanda Howard
Customer Service Representative, Rheumatology

513-803-5254

shalanda.howard@cchmc.org

Kristin R. Huber, DO
Customer Service Representative, Division of Rheumatology

513-636-7667

kristin.huber@cchmc.org

Paula G. Melson, PT, MMSc
Rehabilitation Coordinator, Division of Rheumatology

513-636-4676

paula.melson@cchmc.org

Terry M. Moore, RN II, BSN
Clinical Nurse, Rheumatology Outpatient Center

513-636-4676

terry.moore@cchmc.org

Tracey M. Porter, NA
Customer Service Representataive, Division of Rheumatology

513-636-4676

Tracey.Porter@cchmc.org

LaToya D. Prophet
Financial Service Representative, Division of Rheumatology

513-636-8073

latoya.prophet@cchmc.org

Julie V. Ranz, RN
Registered Nurse, Rheumatology Outpatient Center

513-636-8033

julie.ranz@cchmc.org

Janalee Taylor, RN, MSN, APN, CNS
Associate Clinical Director

513-636-4676

janalee.taylor@cchmc.org

High Res

Janalee Taylor, RN, MSN, APN, CNS

Associate Clinical Director

Nurse Pracitioner, Division of Rheumatology

University of Cincinnati College of Medicine

Phone: 513-636-4676

Fax: 513-636-4116

Email: janalee.taylor@cchmc.org

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Specialties

Care of children with pediatric rheumatic diseases; self-management and patient education; quality improvement and patient outcomes

Education and Training

MSN: Indiana University, Indianapolis, Indiana, 1986.

BSN: Indiana University, Indianapolis, Indiana, 1978.

Publications

View PubMed Publications

Lovell DJ, Passo MH, Beukelman T, Bowyer SL, Gottlieb BS, Henrickson M, Ilowite NT, Kimura Y, DeWitt EM, Segerman J, Stein LD, Taylor J, Vehe RK, Giannini EH. Measuring process of arthritis care: a proposed set of quality measures for the process of care in juvenile idiopathic arthritis. Arthritis Care Res (Hoboken). 2011 Jan;63(1):10-6.

Kocharla L, Taylor J, Weiler T, Ting TV, Luggen M, Brunner HI. Monitoring methotrexate toxicity in juvenile idiopathic arthritis. J Rheumatol. 2009 Dec;36(12):2813-8.

Passo MH, Taylor J. Quality improvement in pediatric rheumatology: what do we need to do? Curr Opin Rheumatol. 2008 Sep;20(5):625-30. Review.

Brunner HI, Taylor J, Britto MT, Corcoran MS, Kramer SL, Melson PG, Kotagal UR, Graham TB, Passo MH. Differences in disease outcomes between medicaid and privately insured children: possible health disparities in juvenile rheumatoid arthritis. Arthritis Rheum. 2006 Jun 15;55(3):378-84.

Barron AC, Lee TL, Taylor J, Moore T, Passo MH, Graham TB, Griffin TA, Grom AA, Lovell DJ, Brunner HI. Feasibility and construct validity of the parent willingness-to-pay technique for children with juvenile idiopathic arthritis. Arthritis Rheum. 2004 Dec 15;51(6):899-908.

Gerhardt CA, Vannatta K, McKellop JM, Taylor J, Passo M, Reiter-Purtill J, Zeller M, Noll RB. Brief report: child-rearing practices of caregivers with and without a child with juvenile rheumatoid arthritis: perspectives of caregivers and professionals. J Pediatr Psychol. 2003 Jun;28(4):275-9.

Gerhardt CA, Vannatta K, McKellop JM, Zeller M, Taylor J, Passo M, Noll RB. Comparing parental distress, family functioning, and the role of social support for caregivers with and without a child with juvenile rheumatoid arthritis. J Pediatr Psychol. 2003 Jan-Feb;28(1):5-15.

Judy A. Thomas
Customer Service Representative, Division of Rheumatology

513-636-4676

judy.thomas@cchmc.org

Research

Michael Barnes, PhD
Research Associate

513-636-1319

michael.barnes@cchmc.org

High Res

Michael Barnes, PhD

Research Associate

Director, Cincinnati Biorepository

University of Cincinnati College of Medicine

Phone: 513-636-1319

Fax: 513-636-3328

Email: michael.barnes@cchmc.org

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Specialties

He is Director of the Cincinnati Biobank Core Facility which provides sample acquisition, processing, storage and distribution services to researchers at the Academic Health Center. Additionally, his research investigates pathologically relevant gene expression changes in children with arthritis (JIA) with the goal is to identify diagnostic and prognostic signatures with clinical utility early in disease.

Education and Training

PhD: University of Cincinnati, Cincinnati, OH, 2001.

BS: Gettysburg College, Gettysburg, PA, 1991.

Publications

View PubMed Publications

Hinze CH, Fall N, Thornton S, Mo JQ, Aronow BJ, Layh-Schmitt G, Griffin TA, Thompson SD, Colbert RA, Glass DN, Barnes MG, Grom AA. Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis. Arthritis Res Ther. 2010;12(3):R123.

Barnes MG, Grom AA, Thompson SD, Griffin TA, Pavlidis P, Itert L, et al. Subtype-specific peripheral blood gene expression profiles in recent onset juvenile idiopathic arthritis. Arthritis Rheum. 2009 Jul;60(7):2102-12.

Griffin TA, Barnes MG, Ilowite N, Olson J, Sherry D, Gottlieb B, et al. Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. Arthritis Rheum. 2009 Jul;60(7):2113-23.

Barnes MG, Aronow BJ, Luyrink LK, Moroldo MB, Pavlidis P, Passo MH, Grom AA, Hirsch R, Giannini EH, Colbert RA, Glass DN, Thompson SD. Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis. Rheumatology (Oxford). 2004 Aug;43(8):973-9.

Wong HR, Shanley TP, Sakthivel B, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A, Kalyanaraman M, Tofil NM, Penfil S, Monaco M, Tagavilla MA, Odoms K, Dunsmore K, Barnes M, Aronow BJ. Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome. Physiol Genomics. 2007;30(2):146-55.

Shanley TP, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A, Kalyanaraman M, Tofil NM, Penfil S, Monaco M, Odoms K, Barnes M, Sakthivel B, Aronow BJ, Wong HR Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock. Mol Med. 2007;13(9):495-508.

Fall N, Barnes M, Thornton S, Luyrink L, Olson J, Ilowite NT, et al. Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum. 2007;56(11):3793-804.

Book Chapters

Meller J, Adamczak R, Scola M, Barnes M, Thompson S, Passo M, et al. Machine learning analysis of expression profiles of synovial tissue cytokines helps identify patients with systemic onset juvenile rheumatoid arthritis. IEmmert-Streib F, Dehmer M (Eds.) in Applications of Statistical and Machine Learning in Bioinformatics: Advances in Computational and Systems Biology. New York: Peter Lang, 2007.

Jamie Chalfin
Research Assistant III, Rheumatology

513-803-5029

jamie.chalfin@cchmc.org

Sarah A. Croswell, BA
Research Assistant, Division of Rheumatology

513-636-7663

Monica L. DeLay, MS
Senior Research Assistant

513-636-4933

monica.delay@cchmc.org

Steve Esslinger
Research Assistant IV, Rheumatology

513-803-5166

steve.esslinger@cchmc.org

Ndate Fall
Research Assistant IV, Division of Rheumatology