Rheumatology

  • Meet the Team

    The Division of Rheumatology at Cincinnati Children's is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child's unique needs.

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    Division Director

    A photo of Dr. John Harley.

    John B. Harley, MD, PhD
    Director, Rheumatology

    513-803-3665

    john.harley@cchmc.org

    John B. Harley, MD, PhD

    Director, Rheumatology

    Professor, UC Department of Pediatrics

    Phone: 513-803-3665

    Email: john.harley@cchmc.org

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    Publications

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    Grants

    Molecular & Immunologic Analysis of the Pathobiology of Human Anthrax. Co-Principal Investigator. National Institute of Allergy and Infectious Diseases. Sep 2009 - Aug 2014. #AI062629-06.

    Genomics of Lupus. Principal Investigator. Aug 2009 - Jul 2014. #1 P01 AI083194-01.

    Oklahoma Autoimmunity Center of Excellence Project 2. Co-investigator. National Institute of Allergy and Infectious Diseases. May 2009 - Apr 2014. #1 U19 AI082714-01.

    Genome-Wide Association Study in African-Americans with Systemic Lupus Erythematosus. Principal Investigator. Department of Defense. Sep 2010- Aug 2013. #PR094002.

    Genomics of Lupus Associations in the Hispanic 12q24 Linkage. Principal Investigator. National Institutes of Health. Jun 2008 - Mar 2013. #5 P01 AR049084-07.

    Lupus Association with Signal Transducer and Activator of Transcription 4. Principal Investigator. US Department of Veterans Affairs. Apr 2008 - Mar 2012.

    Genetic Linkage in Lupus. Principal Investigator. National Institute of Allergy and Infectious Diseases. Feb 2010 - Jan 2012. #3 R37 AI024717-21S1.

    Faculty

    Hermine I. Brunner, MD, MSc

    Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Fax: 513-636-4116

    Email: hermine.brunner@cchmc.org

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    Specialties

    Clinical Interests

    Health-related quality of life; outcome research; lupus

    Research Interests

    Economic analyses; HRQOL; measurement development; outcome research; lupus 

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    Biography

    Hermine Brunner, MD, MSc, is a pediatric rheumatologist with a special clinical and research interest in pediatric lupus. Her research is focused on biomarker discovery and the testing of new medications for lupus. She is also involved in trial design and provides statistical support at Cincinnati Children's. As head of the Lupus Center, she is involved in the conduction of the Lupus Clinic and the organization of Lupus Support Groups. She also pioneers the development of outcome measures and improving the quality of clinical of children with lupus and other rheumatic diseases.

    Education and Training

    MD: Ludwig Maximilan University, Munich, Germany, 1991.

    Residency: University of Chicago, 1997.

    Fellowship: University of Toronto & Cincinnati, 1999.

    MSc: Clinical Epidemiology: University of Toronto, 1999.

    Certification: Pediatrics 1997; Rheumatology 2002.

    Publications

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    Edward H. Giannini, MSc, DrPH

    Professor, UC Department of Pediatrics

    Phone: 513-636-7634

    Email: edward.giannini@cchmc.org

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    Publications

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    Alexei A. Grom, MD

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-3339

    Fax: 513-636-3328

    Email: alexei.grom@cchmc.org

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    Specialties

    Biography

    The research of Alexei Grom, MD, has mainly involved two translational projects focused on two autoimmune diseases – systemic juvenile rheumatoid arthritis and juvenile dermatomyositis. In both projects, recent advances of cellular immunology are applied to these diseases to promote better understanding of their pathogenesis and treatment.

    Systemic Onset Juvenile Rheumatoid Arthritis and an associated condition known as Macrophage Activation Syndrome are severe and often devastating illnesses. The pathological mechanisms are not known but Dr. Alexei Grom has focused his research on NK and cytotoxic cell function in this disease. The rationale for this approach has been based on the strong clinical similarities between MAS and the better understood autosomal recessive disorder familial hemophagocytic lymphohistiocytosis, in which the uncontrolled proliferation of T cells and macrophages has been recently associated with decreased NK cell and cytotoxic cell functions secondary to mutations in the gene encoding perforin. Recent observations suggest as in FHLH, MAS patients also have profoundly depressed NK function. Moreover, a large subgroup of systemic JRA patients has very similar immunologic abnormalities. Combined with the evidence of the immunoregulatory role of NK cells in many immune responses, this suggests that NK dysfunction is relevant to the pathogenesis of MAS. New directions have thus been established for research in this poorly understood disease.

    Juvenile Dermatomyositis is a chronic inflammatory condition involving primarily muscles and skin. The most characteristic feature of JDM is vascular damage associated with the capillary necrosis that eventually leads to capillary loss and tissue ischemia. The project is based on the hypothesis that capillary loss in this condition may be caused by angiostatic chemokines that are prominent in the inflammatory response in the affected muscles.

    Education and Training

    MD: Leningrad (St. Petersburg) Pediatric Medical Institute, Russia, 1986. 

    Residency: Leningrad (St. Petersburg) Medical Institute, Russia, 1988; Children's Hospital Medical Center, Cincinnati, Ohio, 1998. 

    Fellowship: Leningrad (St. Petersburg) Pediatric Medical Institute, Russia, 1991; Children's Hospital Medical Center, Cincinnati, Ohio, 1995. 

    Certification: Pediatrics, 1999.

    Publications

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    Michael Henrickson, MD, MPH

    Clinical Director

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-7686

    Email: michael.henrickson@cchmc.org

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    Specialties

    Health policy; global health; neuropsychiatric-SLE; periodic fever syndromes; systemic JIA; culturally appropriate care; quality measures

    Education and Training

    BA: Emory University, Atlanta, GA, 1980.

    MD: Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, 1984.

    MPH: College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2009.

    Residency: Tripler Army Medical Center, Honolulu, HI, 1984-87.

    Fellowship: Children’s Hospital Medical Center, Cincinnati, OH, 1991-94.

    Certification: American Board of Pediatrics: General Pediatrics, 1988 (recertified 2004). Pediatric Rheumatology, 1994 (recertified 2008). National Board of Public Health Examiners, 2009.   

    Publications

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    A photo of Dr. Jennifer Huggins.

    Jennifer L. Huggins, MD
    Fellowship Program Director, Rheumatology

    513-803-0649

    jennifer.huggins@cchmc.org

    A photo of Dr. Jennifer Huggins.

    Jennifer L. Huggins, MD

    Fellowship Program Director, Rheumatology

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-0649

    Email: jennifer.huggins@cchmc.org

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    Education and Training

    MD: University of Kansas Medical School, Kansas City, Kansas 

    Publications

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    A photo of Daniel Lovell.

    Daniel J. Lovell, MD, MPH
    Associate Director, Division of Rheumatology

    513-636-4676

    daniel.lovell@cchmc.org

    Daniel J. Lovell, MD, MPH

    Associate Director, Division of Rheumatology

    Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Fax: 513-636-5990

    Email: daniel.lovell@cchmc.org

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    Specialties

    Clinical Interests

    Diagnostic evaluation and ongoing care of children with all pediatric onset rheumatic diseases

    Research Interests

    Performance of clinical trials in children with rheumatic diseases; clinical trials methodology; mentoring of junior faculty

    Education and Training

    MD: University of Kansas, Kansas City, Kan., 1978. 

    MPH: University of Texas School of Public Health, Houston, Texas, 1982. 

    Residency: Children's Mercy Hospital, Kansas City, Kan. 

    Fellowship: Baylor College of Medicine, Houston, Texas. 

    Certification: Pediatrics, 1984; Pediatric Rheumatology, 1992.

    Publications

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    Halima Moncrieffe, PhD

    Instructor, UC Department of Pediatrics

    Phone: 513-636-4676

    Email: halima.moncrieffe@cchmc.org

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    Specialties

    Immunoregulation; juvenile idiopathic arthritis; biomarkers of response to medication

    Biography

    Halima Moncrieffe, PhD, is an immunologist who has basic and translational research interests in mechanisms of childhood arthritis susceptibility and immunopathology. She studies how genetic and immunological variants contribute to inflammation and response to medication. A second research focus is investigating mechanisms of immune system suppression with specific interest in regulatory T cell function.

    Education and Training

    PhD: Imperial College London, London, United Kingdom.

    Publications

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    Esi M. Morgan DeWitt, MD, MSCE

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Email: esi.morgan-dewitt@cchmc.org

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    Specialties

    Clinical Interests

    Childhood rheumatic diseases; juvenile idiopathic arthritis; juvenile dermatomyositis; sarcoidosis

    Research Interests

    Patient reported outcomes measure development; quality Improvement; health services research; economic evaluations; comparative effectiveness

    Biography

    Esi Morgan DeWitt, MD, MSCE, is a pediatric rheumatologist and researcher. Clinical care spans the childhood rheumatic diseases, with focus on juvenile idiopathic arthritis (JIA) and juvenile dermatomyositis.

    Her research training and experience includes epidemiology and health services research, in addition to specialization in quality improvement methods and application to improve health care delivery. Dr. Morgan DeWitt leads a research project to develop new measures to assess pain in children and youth, as well as to validate measures of health related quality of life in children with juvenile idiopathic arthritis or chronic pain as part of a national network of investigators.

    Dr. Morgan DeWitt is a leader in a multi-center quality improvement network to improve the outcome of care in children with JIA, the Pediatric-Rheumatology Care and Outcomes Improvement Network. Additionally, she has served on expert panels in development of JIA treatment recommendations and measures of quality of care in treatment of JIA.

    Education and Training

    MD: Washington University School of Medicine, St. Louis, MO, 1999.

    Residency: Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA, 2002.

    Fellowship: Rheumatology, Children’s Hospital of Philadelphia, Philadelphia, PA, 2005.

    MSCE: University of Pennsylvania, Center for Clinical Epidemiology & Biostatistics, Philadelphia, PA, 2005.

    Certification: Pediatrics, 2002; Pediatric Rheumatology, 2006.

    Publications

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    Bahram Namjou-Khales, MD

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-5076

    Email: bahram.namjou@cchmc.org

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    Biography

    Over the past decade, Dr. Namjou-Khales has been involved in research and studying the genetics of lupus and related autoimmune diseases with more than 35 peer-reviewed publications. His background as a physician and his experiences in genomic medicine have been enormously useful to deeply evaluate, successfully identify, and well-characterize subphenotypes and incorporate a wide variety of clinical variables into the genetic analysis. Furthermore, this effort has generated a very interesting bio repository database with comprehensive genomic, clinical and environmental data elements for the analysis of the genetics of lupus and other autoimmune diseases.

    Education and Training

    MD: National University (s.beheshti) of Tehran, Tehran, Iran, 1989.

    Certification: USMLE certified, 1996.

    Publications

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    Susan Thompson, PhD

    Susan Thompson, PhD

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-3899

    Email: susan.thompson@cchmc.org

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    Specialties

    Molecular basis of juvenile rheumatoid arthritis; large-scale integrative analysis of gene expression, polymorphism and other genomic data with clinical data

    Visit the Thompson Lab.

    Biography

    Susan Thompson, PhD, has research interests that span both genetic and functional genomic studies of juvenile rheumatoid arthritis (JRA) to advance the understanding of the causes and mechanisms of disease pathogenesis. A genome-wide screen for JRA susceptibility traits has been completed and defined several regions for linkage mapping and candidate gene analysis. In addition, complementary approaches that measure global gene expression patterns using DNA microarrays are also being used to understand the molecular basis for disease.

    Education and Training

    PhD: University of Tennessee Center for Health Sciences, Memphis, TN, 1988.

    Fellowship: Immunology, St. Jude Children's Research Hospital, Memphis, TN, 1988-1991.

    Fellowship: Molecular Genetics, University of Cincinnati, Cincinnati, OH, 1991-1994.

    Publications

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    Sherry Thornton

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-1318

    Fax: 513-636-3328

    Email: sherry.thornton@cchmc.org

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    Specialties

    Evaluating targets for the treatment of rheumatic disease; angiogenesis; animal models of arthritis

    Visit the Grom-Thornton Lab.

    Education and Training

    BS: Ball State University, Muncie, Indiana.

    PhD: University of Cincinnati, College of Medicine, Cincinnati, OH.

    Postdoctoral Research Fellow: Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

    Publications

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    A photo of Tracy Ting.

    Tracy V. Ting, MD

    513-636-4676

    Tracy V. Ting, MD

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Fax: 513-636-5568

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    Education and Training

    MD: West Virginia University, Morgantown, WV, 2002.

    Residency: Cleveland Clinic, Cleveland, OH, 2005.

    Certification: Pediatrics, 2005.

    Publications

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