Steatohepatitis Center

  • Meet the Team

    The Steatohepatitis Center is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our faculty and staff.

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    Faculty

    A photo of Rohit Kohli.

    Rohit Kohli, MBBS, MS
    Associate Medical Director, Liver Transplant Program

    513-803-7044

    rohit.kohli@cchmc.org

    Rohit Kohli, MBBS, MS

    Associate Medical Director, Liver Transplant Program

    Co-Director, Steatohepatitis Center

    Attending Physician, Liver Care Center

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-7044

    Fax: 513-636-5581

    Email: rohit.kohli@cchmc.org

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    Specialties

    Clinical Interests

    Non-alcoholic steatohepatitis; liver transplantation; mitochondrial hepatopathies

    Research Interests

    Obesity related fatty liver disease (non-alcoholic steatohepatitis)

    Visit the Kohli Lab.

    Biography

    Rohit Kohli, MBBS, MS, is currently an associate professor of pediatrics at the University of Cincinnati College of Medicine and the co-director of the Cincinnati Children's Steatohepatitis Center.

    Dr. Kohli received his medical degree from the Armed Forces Medical College, India in 1999 and his MS in Clinical Investigation from Northwestern University in 2006. While at Northwestern he first spent three years as a Pediatric Gastroenterology and Hepatology fellow and then subsequently as a Transplant Hepatology trainee before relocating to the University of Cincinnati in 2007.

    His research work has focused on the pathogenesis of obesity related fatty liver disease (NAFLD). In particular, he has focused upon the role of reactive oxygen stress in the generation and regulation of the extreme stage of this disease; nonalcoholic steatohepatitis (NASH). Dr. Kohli's laboratory currently focuses on the role of fructose in triggering above mentioned oxidative injury and fibrosis within the liver. He also works with Drs. Randy Seeley and Stephen Woods at the Metabolic Diseases Institute at the University of Cincinnati to understand the mechanism and impact of bariatric surgical procedures on NASH and other co-morbidities of obesity.

    He has published many peer-reviewed articles including articles in The Journal of Biological Chemistry, Hepatology, Journal of Pediatrics, and The American Journal of Physiology. He is the author of many book chapters and review articles. He also is the recipient of the 2007 George Ferry Young Investigator Award from the Children's Digestive Health and Nutrition Foundation and a Fellowship award from the American Association for the Study of Liver Diseases. His clinical efforts are focused within the Steatohepatitis Center and Liver Care Center in the Division of Gastroenterology, Hepatology and Nutrition at Cincinnati Children's Hospital Medical Center.

    Education and Training

    MS: Clinical Investigation, School of Public Health, Northwestern University, IL, 2004-2006.

    MBBS: Armed Forces Medical College, Pune University, India,1993-1999.

    Residency: Metropolitan Hospital, New York Medical College, NY, 2000-2003.

    Fellowship: Gastroenterology, Children's Memorial Hospital, Northwestern University, IL, 2003-2006.

    Fellowship: Transplant Hepatology, Children's Memorial Hospital, Northwestern University, IL, 2006-2007.

    Certification: Pediatrics, 2004; Transplant Hepatology, 2010; Gastroenterology, 2009.

    Publications

    View PubMed Publications
    A photo of Stavra Xanthakos.

    Stavra A. Xanthakos, MD, MS
    Co-Director, Steatohepatitis Center

    513-636-4415

    stavra.xanthakos@cchmc.org

    Stavra A. Xanthakos, MD, MS

    Co-Director, Steatohepatitis Center

    Medical Director, Surgical Weight Loss Program for Teens

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4415

    Fax: 513-636-7805

    Email: stavra.xanthakos@cchmc.org

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    Specialties

    Biography

    Stavra A. Xanthakos, MD, is an assistant professor and attending physician in the Division of Gastroenterology, Hepatology and Nutrition, the co-director of the Cincinnati Children’s Steatohepatitis Center, and the medical director of the Surgical Weight Loss Program for Teens. She also partners with physicians and staff in Cincinnati Children’s Center for Better Health and Nutrition in the evaluation and management of pediatric patients suffering from severe pediatric obesity and related complications.

    Dr. Xanthakos received her medical degree from Duke University in 1997 and a Master of Science degree in molecular epidemiology from the University of Cincinnati in 2006. Her post-doctoral training, including residency, chief residency and fellowship were completed at Cincinnati Children's and she joined the faculty in 2005. During her fellowship, Dr. Xanthakos investigated the prevalence and outcome of non-alcoholic fatty liver disease (NAFLD) in young adult women as her master’s thesis in molecular epidemiology. Her current clinical and translational research is focused on identify the predictors and outcome of obesity-related liver disease (nonalcoholic fatty liver disease and steatohepatitis), in obese adolescents undergoing bariatric surgery. She is also a co-investigator in the NIH sponsored Teen LABS, a multicenter consortium investigating bariatric surgery in adolescents and in the NIH-sponsored NASH Clinical Research Network. Additional research interests of Dr. Xanthakos include the treatment and prevention of pediatric obesity, outcomes of bariatric surgery in adolescents, malnutrition in pediatric obesity, as well as identifying genetic and environmental risk factors for pediatric nonalcoholic fatty liver disease to enable better evaluation and treatment options. She also leads clinical quality improvement initiatives in the Steatohepatitis Center, which are aligned with divisional and institutional initiatives to achieve measurable improvements in children’s health and disease outcomes.

    Dr. Xanthakos has published extensively in the field of pediatric obesity, bariatric medicine and non-alcoholic fatty liver disease. She regularly is invited to speak about pediatric obesity evaluation and management, particularly bariatric medicine, and pediatric nonalcoholic fatty liver disease.

    Education and Training

    MD: Duke University, Durham, NC, 1997.

    MS: Molecular Epidemiology, University of Cincinnati, 2006.

    Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1997-2000.

    Chief Residency: Cincinnati Children's, Cincinnati, OH, 2000-01.

    Clinical Fellowship: Gastroenterology, Hepatology & Nutrition, Cincinnati Children's , Cincinnati, OH, 2001-2004.

    Research Fellowship: Molecular Epidemiology in Children's Environmental Health, Masters of Science, 2002-2005.

    Certification: Pediatrics, 2008; Pediatric Gastroenterology, 2005.

    Publications

    View PubMed Publications

    Grants

    Adolescent Bariatrics: Assessing Health Benefits and Risks. Co-Investigator. National Institutes of Health. July 2006 - April 2011. #U01DK072493.

    Coenzyme Q as a Novel Biomarker for the Severity of Steatohepatitis. Co-Principal Investigator. National Institutes of Health. Jun 2010 - May 2011. #P30DK078392.

    Biological Determinants of Steatohepatitis after Adolescent Bariatric Surgery. Principal Investigator. National Institutes of Health. July 2008 - June 2013. #1K23DK080888.

    Clinical Research Network in Non-Alcoholic Steatohepatitis (NASH CRN). Site Principal investigator. National Institutes of Health. Aug 2009 - Apr 2014. #U01DK061732.