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Clinical Faculty

Maria H. Alonso-Peclet, MD
Surgical Director, Kidney Transplant Program

513-636-4371

maria.alonso@cchmc.org

Richard G. Azizkhan, MD
Surgeon-in-Chief; Lester W. Martin Chair of Pediatric Surgery

513-636-4576

richard.azizkhan@cchmc.org

High Res

Richard G. Azizkhan, MD

Surgeon-in-Chief; Lester W. Martin Chair of Pediatric Surgery

Professor

Professor, Division of Pediatric Surgery

Phone: 513-636-4576

Fax: 513-636-7657

Email: richard.azizkhan@cchmc.org

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Specialties

Clinical Interests

Complex mediastinal airway disorders; surgical oncology; neonatal anomalies; chest wall deformities; vascular malformations; esophageal disorders; pediatric trauma; epidermolysis bullosa

Research Interests

Trauma systems; injury prevention; fetal lung development; vascular malformations; solid tumors in childhood

Biography

Richard G. Azizkhan, MD, PhD (Hon), is the surgeon-in-chief at Cincinnati Children’s Hospital Medical Center. He is the first occupant of the Lester W. Martin Chair of pediatric surgery and is a professor of surgery and pediatrics at the University of Cincinnati, College of Medicine.

Dr. Azizkhan has published extensively and is author of more than 200 papers and chapters, and four books. Dr. Azizkhan’s experience and innovations in the management of complex mediastinal airway disorders, surgical oncology, neonatal anomalies, chest wall deformities, vascular malformations, epidermolysis bullosa, esophageal disorders and pediatric trauma have led to international recognition and numerous awards.

Dr. Azizkhan has served in leadership roles in numerous national and international surgical organizations including the American Academy of Pediatrics’ Surgical Section, American Pediatric Surgical Association and the American College of Surgeons. He is currently President of the World Federation of Associations of Pediatric Surgeons (WOFAPS). He has been active in establishing international medical education exchange programs and medical humanitarian activities in Central Europe, the Middle East, Latin America, Asia and Africa. One of his most significant opportunities was to be one of the 8 USAID supported coordinators of the medical reconstruction of the health care system in central Bosnia Herzegovina after the war ended in 1995. His work and relationship with academic health centers, national and regional health ministries throughout the Balkans is maintained actively today through the Cincinnati Children’s /Tuzla University and Zagreb Children’s Hospital affiliations which he coordinates. He was awarded an Honorary PhD from Tuzla University in 2001 and honorary citizenship of Tuzla in 2006 for his continuing contributions to improving the health system in Bosnia and all of the former Yugoslavian republics. He received the R. K. Ghandi Gold medal in 2005 from the Indian Association of Pediatric Surgeons for his impact globally.

Education and Training

MD: Doctor of Medicine, Milton S. Hershey Center of Pennsylvania State University College of Medicine Hershey, PA, 1972 to 1975.

Residency: Pediatric Surgery, Johns Hopkins Hospital, Baltimore, MD; Surgery, University of Virginia Medical Center, Charlottesville, VA.

Fellowship: Department of Surgery, Children's Hospital Medical Center, Harvard Medical School, Boston, MA.

Certification: General Surgery, 1984, recertified 1992; Pediatric Surgery, 1986, recertified 1993; Surgical Critical Care, 1989.

Sean J. Barnett, MD, MS
Pediatric Surgeon

513-636-4371

sean.barnett@cchmc.org

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Sean J. Barnett, MD, MS

Pediatric Surgeon

Assistant Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Fax: 513-636-4657

Email: sean.barnett@cchmc.org

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Specialties

Clinical Interests

Minimally invasive surgery; neonatal surgery; bariatric surgery; surgical oncology; medical innovation and instrument design

Research Interests

Medical and surgical innovation; instrument design

Biography

Sean J. Barnett, MD, MS, is an Assistant Professor with the Division of Pediatric General and Thoracic Surgery at Cincinnati Children’s Hospital Medical Center. He obtained his Bachelor of Science degree in Mechanical Engineering from Purdue University and his Master’s of Science in Human Anatomy from Wright State University. He completed his medical degree at The Boonshoft School of Medicine. His surgical internship and general surgery residency were completed at the University of Minnesota Hospitals and Clinics in Minneapolis, Minnesota. Additionally, he completed a two year fellowship in surgical infectious diseases while at the University of Minnesota. Most recently, he was a pediatric surgery fellow at Cincinnati Children’s Hospital Medical Center. Dr. Barnett has a special interest in minimally invasive surgery, neonatal surgery, bariatric surgery, and medical innovation.

Education and Training

BSME: Mechanical Engineering, Purdue University, West Lafayette, IN, 1993

MS: Human Anatomy, Wright State University, Dayton, OH, 1996

MD: Boonshoft School of Medicine, Dayton, OH, 2000

Residency: General Surgery, University of Minnesota School of Medicine, Minneapolis, MN

Fellowship: Pediatric Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Certification: General Surgery, 2008

Publications

View PubMed Publications

Dauplaise DJ, Barnett SJ, Frischer JS, Wong HR. Decompressive abdominal laparotomy for abdominal compartment syndrome in an unengrafted bone marrow recipient with septic shock. Crit Care Res Pract. 2010; pii: 102910.

Bischoff A, Gupta A, D'Mello S, Mezoff A, Podberesky D, Barnett S, Keswani S, Frischer JS. Crohn's disease limited to the appendix: a case report in a pediatric patient. Pediatr Surg Int. 2010 Nov;26(11):1125-8.

Leslie DB, Kellogg TA, Boutelle KN, Barnett SJ, Schwarzenberg SJ, Harrison AR, Ikramuddin S. Preserved Vision Without Growth Retardation After Laparoscopic Roux-en-Y Gastric Bypass in a Morbidly Obese Child with Pseudotumor Cerebri: 36-month Follow-up . Journal of Pediatric Surgery. 2008;43(7):e27-30.

Whitson BA, Huddleston SJ, Barnett SJ, Mohr WJ. Vacuum Induced Arm Compartment Syndrome and Pulmonary Embolism. Journal of Burn Care & Research. 2006;27(4): 552-4.

Rivard AL, Simura KJ, Mohammad S, Magembe AJ, Pearson HM, Hallman MR, Barnett SJ, Gatlin D, Gallegos RP, Bianco RW. Rodent Intubation and Ventilation for Surgical Research. Journal of Investigative Surgery. 2006;19(4):267-274.

Barnett SJ, Stanley C, Hanlon M, Acton RD, Saltzman DA, Ikramudin S, Buchwald H. Long Term Follow-Up and the Role of Surgery in Adolescents with Morbid Obesity. Surgery for Obesity and Related Disorders (SOARD). 2005;1(4): 394-398.

Barnett SJ, Soto III LJ, Sorenson BS, Nelson BW, Leonard AS, Saltzman DA. Salmonella typhimurium Invades and Decreases Tumor Burden in Neuroblastoma. Journal of Pediatric Surgery. 2005;40(6): 993-998.

Rebeccah L. Brown, MD
Associate Director, Trauma Services

513-636-4371

rebeccah.brown@cchmc.org

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Rebeccah L. Brown, MD

Associate Director, Trauma Services

Associate Professor, UC Department of Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: rebeccah.brown@cchmc.org

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Specialties

Clinical Interests

General pediatric surgery; trauma; injury prevention; minimally invasive surgery; necrotizing enterocolitis; neonatal surgery; minimally invasive surgery; congenital hemolytic anemias; chest wall deformities

Research Interests

Pediatric trauma; injury prevention

Biography

Rebeccah L. Brown, MD, received a Bachelor of Science in Biology and Bachelor of Arts in Chemistry at New Mexico State University in Las Cruces, NM, in 1986. She graduated from University of New Mexico School of Medicine in Albuquerque, NM, with an MD in 1990. She completed her general surgery residency at University of Cincinnati Medical Center, in Cincinnati, Ohio, in 1997.

During her general surgical training, she also performed two years of basic science and clinical research in burn injuries and wound healing at the Shriners Hospitals for Children -- Cincinnati. She also served as an extracorporeal membrane oxygenation (ECMO) fellow at Cincinnati Children's Hospital Medical Center.

After completion of general surgery training, Dr. Brown completed a two-year fellowship in Pediatric Surgery at Children's Hospital of Buffalo in Buffalo, N.Y. She returned to Cincinnati Children's, Ohio, as assistant professor of Surgery and Pediatrics. Her main research interest is trauma and injury prevention, and she is currently the assistant director of Trauma Services, the fellowship director for the Pediatric Trauma Fellowship, and the director and cofounder of the Buckle Up for Life or Abrochate a la Vida program funded by Toyota.

Dr. Brown's clinical interests besides trauma and injury prevention include general pediatric surgery, minimally invasive surgery, inflammatory bowel disease, and Hirschsprung's disease.

Dr. Brown is a member of multiple professional organizations including the American College of Surgeons, American Medical Association, American Medical Women's Association, American College of Surgeons -- Ohio Chapter, Cincinnati Pediatric Society, Mont Reid Surgical Society, American Pediatric Surgical Association, American Academy of Pediatrics - Surgical Section and Injury Prevention Section, Eastern Association for the Surgery and Trauma, and Pediatric Trauma Society.

Education and Training

MD: University of New Mexico School of Medicine, Albuquerque, N.M., 1990.

Residency: General Surgery, University of Cincinnati Hospital, Cincinnati, Ohio, 1997.

Fellowship: Shriners Burns Institute, Cincinnati, Ohio, 1992-1994; ECMO, Children's Hospital Medical Center, Cincinnati, Ohio, 1993-1994; Pediatric Surgery Fellow, Children's Hospital of Buffalo, Buffalo, N.Y., 1997-1999.

Certification: Board-certified General Surgery, 1998, 2007; board-certified, Pediatric Surgery, 2000, 2009.

A. Roshni Dasgupta, MD, MPH
Pediatric Surgeon

513-636-4371

roshni.dasgupta@cchmc.org

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A. Roshni Dasgupta, MD, MPH

Pediatric Surgeon

Associate Professor, UC Department of Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: roshni.dasgupta@cchmc.org

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Specialties

Clinical Interests

Surgical oncology and vascular malformations; minimally invasive surgery; general pediatric surgery

Research Interests

oncology and vascular malformations

Education and Training

MD: University of Toronto, Toronto Canada, 1996

Residency: Massachusetts General Hospital, Harvard Medical School 1996-2003

Research Fellowship: University of Oxford, Oxford England

Fellowship: Hospital for Sick Children, Toronto, Canada

MPH: Harvard School of Public Health, Boston, MA, 2009.

Publications

View PubMed Publications

Murrell Z, Dasgupta R. What predicts the risk of recurrent lung metastases? J Pediatr Surg. 2013 May;48(5):1020-4.

Burke ME, LydenER, Meza^,JL, Ladas EJ, Dasgupta R, Wiegner EA, Arndt CA. Does Body Mass Index at Diagnosis or Weight Change during Therapy Predict Toxicity or Survival in Intermediate Risk Rhabdomyosarcoma? A Report from The Children’s Oncology Group Soft Tissue Sarcoma Committee. Pediatr Blood Cancer. 2013 May;60(5):748-53.

Chen W, Gupta A, Adams D, Patel M, Dasgupta R. Generalized lymphatic malformation with chylothorax: long-term management of a highly morbid condition in a pediatric patient. J Pediatr Surg. 2013 Mar;48(3):e9-e12.

Gupta AA, Anderson JR, Pappo AS, Spunt SL, Dasgupta R, Indelicato DJ, Hawkins DS. Patterns of Chemotherapy-Induced Toxicities in Younger Children and Adolescents with Rhabdomyosarcoma: A Report from the Children’s Oncology Group Soft Tissue Sarcoma Committee. Cancer. 2012 Feb 15;118(4):1130-7.

Dasgupta R, Rodeberg DA. Update on Rhabdomyosarcoma. Semin Pediatr Surg. 2012 Feb;21(1):68-78.

Rymeski B, Burns K, Nagarajan R, Correll J, Kent D, O'Brien M, Perentesis JP, Dasgupta R. Long-term complications after staging laparotomy for Hodgkin lymphoma. J Clin Oncol. 2012.

Hammill A, Wentzel M, Gupta A, Nelson S, Lucky A, Elluru R, Dasgupta R, Azizkhan R, Adams D. Sirolimus for the treatment of complicated vascular anomalies in children. Pediatr Blood Cancer. 2011 Dec 1;57(6):1018-24.

Chen W, Wagner L, Boyd T, Nagarajan R, Dasgupta R. Extra-lobar pulmonary sequestration presenting with torsion: a case report and review of literature. J Pediatr Surg. 2011 Oct;46(10):2025-8.

Weiss BD, Dasgupta R, Gelfand MJ, Laor T, Yin H, Breneman JC, Lavigne R, Elluru RG, Wagner LM. Use of sentinel lymph node biopsy for staging para-meningeal rhabdomyosarcoma. Pediatr Blood Cancer. 2011 Sep;57(3):520-3.

Murrell Z, Dickie B, Dasgupta R. Lung Nodules in Pediatric Oncology Patients: A Prediction Rule for When to Biopsy. J Pediatri Surg. 2011 May;46(5):833-7.

Richard A. Falcone Jr., MD, MPH
Director, Trauma Services

513-636-4371

richard.falcone@cchmc.org

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Richard A. Falcone, MD, MPH

Director, Trauma Services

Associate Professor

Associate Professor, UC Department of Pediatric Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: richard.falcone@cchmc.org

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Specialties

Clinical Interests

Pediatric injury prevention and outcomes; trauma education; management of colorectal disorders; inflammatory bowel disease; minimally invasive surgery; surgical oncology; extracorporeal life support (ECLS)

Research Interests

Injury prevention; health disparities; pediatric colorectal disorders; use of simulation to improve teamwork and safety

Education and Training

MPH: Harvard School of Public Health, Boston, MA, 2007.

MD: New York University School of Medicine, 1995.

General Surgery Residency: University of Cincinnati, 1995-2002.

Pediatric Surgery Fellowship: Cincinnati Children's Hospital Medical Center, 2002-2004.

Certification: Surgery 2004; Pediatric Surgery 2006.

Publications

View PubMed Publications

Cook R, Gillespie GL, Kronk, R, Daugherty M, Moody SM, Allen LJ, Shebesta KB, Falcone RA. Effect of an Educational Intervention on Nursing Staff Knowledge, Confidence, and Practice in the Care of Children with Mild Traumatic Brain Injury. Neuronurse. 2013 Apr;45(2):108-18.

Daugherty MC, Mehlman CT, Moody S, LeMaster T, Falcone RA Jr. Significant Rate Of Misuse Of The Hare Traction Splint For Children With Femoral Shaft Fractures. J Emerg Nurs. 2013 Jan;39(1):97-103.

Chatoorgoon K, Brown RL, Garcia VF, Falcone RA. Role of Computed Tomography and Clinical Findings in Pediatric Blunt Intestinal Injury: A Multi-Center Study. Pediatric Emergency Care. 2012 Dec;28(12):1338-42.

Beaudin M, Daugherty M, Geis G, Moody S, Brown RL, Garcia VF, Falcone RA Jr. Assessment of factors associated with the delayed transfer of pediatric trauma patients: an emergency physician survey. Pediatr Emerg Care. 2012 Aug;28(8):758-63.

Falcone RA Jr, Haas L, King E, Moody S, Crow J, Moss A, Gaines B, McKenna C, Gourlay DM, Werner C, Meagher DP Jr, Schwing L, Garcia N, Brown D, Groner JI, Haley K, Deross A, Cizmar L, Armola R. A multicenter prospective analysis of pediatric trauma activation criteria routinely used in addition to the six criteria of the American College of Surgeons. J Trauma Acute Care Surg. 2012 Aug;73(2):377-84; discussion 384.

Burton KS, Pendergrass TL, Byczkowski TL, Taylor RG, Moyer MR, Falcone RA, Geis GL. Impact of Simulation-Based Extracorporeal Membrane Oxygenation Training in the Simulation Laboratory and Clinical Environment. Simul Healthc. 2011 Oct;6(5):284-91.

Goldberg, J, McClaine RJ, Cook B, Garcia VF, Brown RL, Crone K, Falcone RA. Use of a mild traumatic brain injury guidelines to reduce inpatient hospital imaging and charges. J Pediatr Surg. 2011 Sep;46(9):1777-83.

Lawal TA, Falcone RA, von Allmen D, Denson LA, Levitt MA, Warner BW, Frischer JS. The utility of routine pouchogram before ileostomy reversal in children and adolescents following ileal pouch anal anastomosis. J Pediatr Surg. 2011 Jun;46(6):1222-5.

Jason S. Frischer, MD
Director, Extracorporeal Membrane Oxygenation Program, Division of Pediatric General and Thoracic Surgery

513-636-4371

jason.frischer@cchmc.org

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Jason S. Frischer, MD

Director, Extracorporeal Membrane Oxygenation Program, Division of Pediatric General and Thoracic Surgery

Assistant Professor, UC Department of Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: jason.frischer@cchmc.org

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Specialties

Colorectal surgery including Inflammatory Bowel Disease (IBD, Crohn's disease and Ulcerative Colitis); ECMO; congenital diaphragmatic hernia (CDH); neonatal surgery; minimally invasive surgery; Epidermolysis Bullosa (EB)

Biography

Jason S. Frischer, MD, is an assistant professor in the Division of Pediatric General and Thoracic Surgery at Cincinnati Children's Hospital Medical Center. He earned his medical degree at SUNY Downstate Medical Center. His surgical internship and general surgery residency were completed at the Mount Sinai School of Medicine in New York. Additionally, he spent two years as an ECMO fellow and a postdoctoral research fellow in tumor biology at the Children’s Hospital of New York, Columbia University. He went on to complete his pediatric surgery training at the Children’s Hospital of New York, Columbia University.

Dr. Frischer has a special interest in colorectal surgery including Inflammatory Bowel Disease (IBD, Crohn's disease and Ulcerative Colitis), Hirschsprung’s disease and anorectal malformations (ARM) and is member of the Colorectal Center as well as the Epidermolysis Bullosa (EB) Center. He serves as the director of the ECMO program and is a member of the congenital diaphragmatic hernia (CDH) team. He has an interest in neonatal surgery and laparoscopy.

Dr. Frischer is a member of Alpha Omega Alpha (national medical honor society) and was selected by Cincy Magazine Best Doctors in 2010 and 2011. He also was selected by Castle Connolly Medical Ltd. and U.S. News & World Report “Top Doctors” in 2012.

Education and Training

BS: Cornell University, Ithaca, NY, 1995.

MD: SUNY Downstate Medical Center, Brooklyn, NY, 1999.

Residency: Mount Sinai School of Medicine, The Mount Sinai Hospital, New York, NY, 2000-2001 and 2003-2006.

ECMO/Research Fellowship: Children's Hospital of New York - Presbyterian, Columbia University, New York, NY, 2001-2003.

Pediatric Surgery Residency: Children's Hospital of New York – Presbyterian, Columbia University, New York, NY, 2006-2008.

Certification: General Surgery, 2007; Pediatric Surgery, 2010.

Publications

View PubMed Publications

Chernoguz A, Crawford, K, Vandersall A, Willson T, Denson LA, Frischer JS. Pre-treatment with Anti-VEGF therapy may exacerbate inflammation in experimental acute colitis. J Pediatr Surg. 2012 Feb;47(2):347-54.

Le LD, Keswani SG, Biesiada J, Lim FY, Kingma PS, Haberman BE, Frischer J, Habli M, Crombleholme TM. The congenital diaphragmatic hernia composite prognostic index correlates with survival in left-sided congenital diaphragmatic hernia. J Pediatr Surg. 2012 Jan;47(1):57-62.

Chernoguz A, Crawford KM, Donovan EC, Vandersall AE, Berglund C, Cripe TP, Frischer JS. EGFR Inhibition Fails to Suppress Vascular Proliferation and Tumor Growth in a Ewing’s Sarcoma Model. J Surg Res. 2012 Mar;173(1):1-9.

Lawal TA, Frischer JS, Falcone RA, Chatoorgoon K, Denson LA, Levitt MA. The transanal approach with laparoscopy or laparotomy for the treatment of rectal strictures in Crohn’s disease. J Laparoendosc Adv Surg Tech A. 2010 Nov;20(9):791-5.

Bischoff A, Gupta A, D’Mello S, Mezoff A, Podberesky D, Barnett S, Keswani S, Frischer JS. Crohn’s disease limited to the appendix: a case report in a pediatric patient. Pediatr Surg Int. 2010 Nov;26(11):1125-8.

Vuletin JF, Lim FY, Cnota J, Kline-Fath B, Salisbury S, Haberman B, Kingma P, Frischer JS, Crombleholme T. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. J Pediatr Surg. 2010 Apr;45(4):703-8.

Frischer JS, Lee A, Serur A, Huang J, Bae JO, Kornfield ZN, Eljuga L, Shawber CJ, Feirt N, Mansukhani M, Stempak D, Baruchel S, Bender JG, Kandel JJ, Yamashiro DJ. Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling. Cancer Res. 2006 Apr;66(8):4378-84.

Frischer JS, Huang J, Serur A, Kadenhe-Chiweshe A, McCrudden KW, O’Toole K, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. Int J Onc. 2004 Sep;25(3):549-53.

Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O’Toole K, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Regression of established tumors and metastases by potent vascular endothelial growth factor blockade. Proc Natl Acad Sci USA. 2003 June 24;100(13):7785-90.

Victor F. Garcia, MD
Founding Director, Trauma Services

513-636-4371

victor.garcia@cchmc.org

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Victor F. Garcia, MD

Founding Director, Trauma Services

Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: victor.garcia@cchmc.org

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Specialties

Pediatric injury research and control; chest-wall deformities; minimally invasive surgery (use of the laparoscope and thoracoscope to diagnose and treat surgical diseases); surgical weight loss; minority health care

Biography

Pediatric Surgeon Victor Garcia, MD, is the founding director of Trauma Services at Cincinnati Children's Hospital Medical Center and a professor for the Division of Pediatric Surgery. He is the co-chair for the Cincinnati CoreChange Initiative.

Education and Training

MD: University of Pennsylvania, School of Medicine, Philadelphia, PA, 1974.

Residency: Walter Reed Army Medical Center, Washington, DC, 1978.

Fellowship: Children's Hospital of Philadelphia, Philadelphia, PA.

Certification: Surgery, 1979; Pediatric Surgery, 1982; Surgical Critical Care, 1991.

Publications

View PubMed Publications

Garcia V. Comment on: Laparoscopic Roux-en-Y gastric bypass versus laparoscopic adjustable gastric banding: five years of follow-up. Surg Obes Relat Dis. 2010 Sep-Oct;6(5):475-6.

Chatoorgoon K, Huezo K, Rangel E, François N, Schweer L, Daugherty M, Koehn M, Ricketts C, Brown RL, Garcia VF, Falcone RA Jr. Unnecessary imaging, not hospital distance, or transportation mode impacts delays in the transfer of injured children. Pediatr Emerg Care. 2010 Jul;26(7):481-6.

Martin CA, Care M, Rangel EL, Brown RL, Garcia VF, Falcone RA Jr. Severity of head computed tomography scan findings fail to explain racial differences in mortality following child abuse. Am J Surg. 2010 Feb;199(2):210-5.

Inge TH, Jenkins TM, Zeller M, Dolan L, Daniels SR, Garcia VF, Brandt ML, Bean J, Gamm K, Xanthakos SA. Baseline BMI is a strong predictor of nadir BMI after adolescent gastric bypass. J Pediatr. 2010 Jan;156(1):103-108.e1.

Inge TH, Miyano G, Bean J, Helmrath M, Courcoulas A, Harmon CM, Chen MK, Wilson K, Daniels SR, Garcia VF, Brandt ML, Dolan LM. Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents. Pediatrics. 2009 Jan;123(1):214-22.

Falcone RA Jr, Martin C, Brown RL, Garcia VF. Despite overall low pediatric head injury mortality, disparities exist between races. J Pediatr Surg. 2008 Oct;43(10):1858-64.

Falcone RA Jr, Daugherty M, Schweer L, Patterson M, Brown RL, Garcia VF. Multidisciplinary pediatric trauma team training using high-fidelity trauma simulation. J Pediatr Surg. 2008 Jun;43(6):1065-71.

Ippisch HM, Inge TH, Daniels SR, Wang B, Khoury PR, Witt SA, Glascock BJ, Garcia VF, Kimball TR. Reversibility of cardiac abnormalities in morbidly obese adolescents. J Am Coll Cardiol. 2008 Apr 8; \51(14):1342-8.

Rangel SJ, Martin CA, Brown RL, Garcia VF, Falcone RA Jr. Alarming trends in the improper use of motor vehicle restraints in children: implications for public policy and the development of race-based strategies for improving compliance. J Pediatr Surg. 2008 Jan;43(1):200-7.

Falcone RA Jr, Brown RL, Garcia VF. Disparities in child abuse mortality are not explained by injury severity. J Pediatr Surg. 2007 Jun;42(6):1031-6; discussion 1036-7.

Michael A. Helmrath, MD, MS
Surgical Director, Intestinal Rehabilitation Program

513-636-4371

michael.helmrath@cchmc.org

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Michael A. Helmrath, MD, MS

Surgical Director, Intestinal Rehabilitation Program

Director of Surgical Research

Professor, UC Department of Surgery

Phone: 513-636-4371

Email: michael.helmrath@cchmc.org

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Biography

As a pediatric surgeon, Dr. Helmrath has dedicated his career to the care of patients with intestinal failure. The main focus of his laboratory is directed towards characterizing intestinal stem cells during intestinal adaptation and developing intestinal regenerative strategies. By combining his clinical experience as the surgical director of intestinal research and rehabilitation at Cincinnati Children’s Hospital, his long-term goal is to establish translational therapies for the management of patients with short bowel syndrome.

Education and Training

BA: Miami University, Oxford, OH, 1987.

MD: University of Cincinnati College of Medicine, Cincinnati, OH, 1993.

MS: University of Cincinnati College of Medicine, Cincinnati, OH, 1989.

Certification: Board-certified General Surgery; board-certified, Pediatric Surgery.

Publications

View PubMed Publications

Helmrath MA, Shin CE, Fox JW, Erwin CR, Warner BW. Adaptation after small bowel resection is attenuated by sialoadenectomy: The role for endogenous epidermal growth factor. Surgery. 1998;124 (5):848-854.

Erwin CR, Helmrath MA, Shin CE, Falcone RA Jr., Stern LE, Warner BW. Intestinal overexpression of EGF in transgenic mice enhances adaptation after small bowel resection. Am J Physiol Gastrointest Liver Physiol. 1999;277:G533-G540.

Helmrath MA, Fong JJ, Dekaney CM, Henning SJ. Rapid expansion of intestinal secretory lineages following a massive small bowel resection in mice. Am J Physiol Gastrointest Liver Physiol. 2007;292(1): G215-222.

Shroyer NF, Helmrath MA, Wang YYC, Antalffy B, Henning SJ, Zoghbi HY. Intestine specific ablation of Math 1 in mice reveals a role in cellular homeostasis. Gastroenterology. 2007;132(7):2478-2488.

Dekaney CM, Fong JJ, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice. Am J Physiol Gastrointest Liver Physiol. 2007;293(5): G1013-22.

Dekaney CM, von Allmen DC, Garrison AP, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileocecal resection. Surgery. 2008;144(2):174-81.

Garrison AP, Dekaney CM, von Allmen DC, Lund PK, Henning SJ, Helmrath MA. Early but not late administration of glucagons-like peptide-2 following ileocecal resection augments putative intestinal stem cell expansion. Am J Physiol Liver Physiol. 2009;296(3): G643-50.

Rigby RJ, Hunt MR, Scull BP, Simmons JG, Speck KE, Helmrath MA, Lund PK. A new animal model of postsurgical bowel inflammation and fibrosis: the effect of commensal microflora. Gut. 2009;58(8);1104-12.

Garrison AP, Helmrath MA, Dekaney CM. Intestinal Stem Cells. J Pediatr Gastroenterol Nutr. 2009;49(1):2-7.

Speck KE, Garrison AP, Rigby RJ, von Allmen DC, Lund PK, Helmrath MA. Inflammation enhances resection-induced intestinal adaptive growth in IL-10 null mice. J Surg Research. 2011;168(1):62-69.

Grants

Mechanisms of intestinal stem cell expansion following resection. Principal Investigator. National Institute of Diabetes and Digestive and Kidney Disease. Jul 2009 - June 2014. #R01DK083325.

Collaborative approach to the study of intestinal epithelial stem cells. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. Sep 2009 - Aug 2014. #1U01DK085547.

Neointestine from live donors & pluripotent stem cells. Co-investigator. CCST University of Cincinnati. 07/01/11 – 06/30/11.

Adolescent Bariatrics: Assessing Health Benefits & Risk. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. 11/01/11 – 10/31/16. U01 DK072493.

Human Endocrine Cell Development. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. 04/01/12 – 03/31/17. R01 DK092456.

Belinda Hsi Dickie, MD, PhD
Colorectal Center

513-636 3240

belinda.dickie@cchmc.org

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Belinda Hsi Dickie, MD, PhD

Colorectal Center

Assistant Professor, UC Department of Pediatrics

Phone: 513-636 3240

Email: belinda.dickie@cchmc.org

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Specialties

Colorectal surgery; vascular malformations; minimally invasive surgery; general pediatric surgery

Biography

Belinda Hsi Dickie, MD, PhD, is an assistant professor with the Division of Pediatric General and Thoracic Surgery at Cincinnati Children's Hospital Medical Center. She obtained her medical degree at the University of Toronto, Ontario Canada and subsequently did her general surgery residency, and completed her PhD, at the University of Alberta, Alberta, Canada. Dr. Dickie continued her training at the University of Alberta, with a fellowship in advanced minimally invasive surgery. She then relocated to the United States where she continued her training and completed fellowships in pediatric vascular malformations and pediatric colorectal surgery at Cincinnati Children’s Hospital Medical Center. She has recently completed her training in pediatric surgery at the University of Florida. She was recruited back to Cincinnati Children’s Hospital in 2011.

Dr. Hsi Dickie has a special interest in the medical and surgical treatment of vascular malformations, pediatric colorectal surgery (including Hirschsprung’s Disease, inflammatory bowel disease, anorectal malformations) and minimally invasive surgery. She also has a lab in vascular biology looking at the genetics and molecular pathways involved with lymphangiogenesis, and the development of vascular malformations

Education and Training

MD: University of Toronto, Toronto,Ontario, Canada 1998.

Residency: General Surgery, University of Alberta, Edmonton, Alberta, Canada.

Fellowship: Advanced Minimally Invasive Surgery, University of Alberta, Edmonton, Alberta, Canada; Vascular anomalies, Cincinnati Children's, Cincinnati, OH; Pediatric Colorectal Surgery, Cincinnati Children's, Cincinnati, OH; Pediatric Surgery, University of Florida Gainesville, Florida,

Certification: General Surgery, 2006; Pediatric Surgery, 2011.

Publications

View PubMed Publications

Levitt MA, Dickie B, Peña A. Evaluation and treatment of the patient with Hirschsprung disease who is not doing well after a pull-through procedure. Semin Pediatr Surg. 2010 May;19(2):146-53.

Dickie B, Dasgupta R, Nair R, Alonso MH, Ryckman FC, Tiao GM, Adams DM, Azizkhan RG. Spectrum of hepatic hemangiomas: management and outcome. J Pediatr Surg. 2009 Jan;44(1):125-33.

Kneteman NM, Weiner AJ, O'Connell J, Collett M, Gao T, Aukerman L, Kovelsky R, Ni ZJ, Zhu Q, Hashash A, Kline J, Hsi B, Schiller D, Douglas D, Tyrrell DL, Mercer DF. Anti-HCV therapies in chimeric scid-Alb/uPA mice parallel outcomes in human clinical application. Hepatology. 2006 Jun;43(6):1346-53.

Hao C, Song JH, Hsi B, Lewis J, Song DK, Petruk KC, Tyrrell DL, Kneteman NM. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res. 2004 Dec 1;64(23):8502-6.

Hsu EC, Hsi B, Hirota-Tsuchihara M, Ruland J, Iorio C, Sarangi F, Diao J, Migliaccio G, Tyrrell DL, Kneteman N, Richardson CD. Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers. Nat Biotechnol. 2003 May;21(5):519-25.

Thomas H. Inge, MD, PhD, FACS, FAAP
Surgical Director, Surgical Weight Loss Program for Teens

513-636-4371

thomas.inge@cchmc.org

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Thomas H. Inge, MD, PhD, FACS, FAAP

Surgical Director, Surgical Weight Loss Program for Teens

Director, Center for Bariatric Research and Innovation

Attending Surgeon, Cincinnati Children’s Hospital Medical Center

Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: thomas.inge@cchmc.org

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Specialties

Obesity surgery and research; neonatal surgery; gastroesophageal reflux disease; minimally invasive surgery; thoracic surgery

Biography

Thomas H. Inge, MD, PhD, is a Virginia native who grew up in a rural, farming community in Dinwiddie County. He received his BS in Biology at the College of William and Mary in Williamsburg, VA, in 1987. Dr. Inge entered the Medical College of Virginia in Richmond, VA, in the Medical Scientist Training Program, and pursued degrees in Microbiology / Immunology and Medicine. He graduated with MD and PhD degrees in 1993.

Dr. Inge received his surgical training at Stanford University Hospital in Palo Alto, CA, where he developed an interest in pediatric surgery. At the completion of his chief resident year in 1998, he moved to Birmingham, AL, for specialty training in pediatric surgery at the Children's Hospital of Alabama, with an emphasis on pediatric minimally invasive surgery. Dr. Inge became a full-time member of the surgical staff at Cincinnati Children's Hospital Medical Center and faculty member of the University of Cincinnati College of Medicine, Department of Surgery, Division of Pediatric Surgery, in July 2000.

In addition to general pediatric surgical practice, Dr. Inge's clinical research focus is related to bariatric surgery in adolescents. He is the surgical director of the Surgical Weight Loss Program for Teens, offering surgery for overweight adolescents with complications from their excess weight. He has served as a consultant to the Food and Drug Administration for projects related to device treatment of pediatric obesity. He is also the Principal Investigator of two research projects funded by National Institutes of Health (NIH) and co-investigator of another NIH funded project examining the role of surgery for management of adolescent obesity. He currently serves as Study Chairman of Teen-LABS, a multicenter research consortium examining outcomes of adolescent bariatric surgery.

Dr. Inge has given over 50 invited lectures nationally and internationally over the past four years, has mentored more than a dozen fellows and students, and has authored more than 70 published chapters and manuscripts.

Education and Training

BS: College of William and Mary, Williamsburg, VA, 1987.

MD: Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, 1993.

PhD: Virginia Commonwealth University, Richmond, VA, 1993.

Residency: Stanford University Hospital, Stanford, CA, 1998.

Fellowship: Children's Hospital of Alabama, Birmingham, AL, 2000.

Board Certification: Diplomate of the American Board of Surgery, December 1999; Certification in Pediatric Surgery, American Board of Surgery, March 2002.

Publications

View PubMed Publications

Zeller MH, Guilfoyle SM, Reiter-Purtill J, Ratcliff MB, Inge TH, Long JD. Adolescent bariatric surgery: caregiver and family functioning across the first postoperative year. Surg Obes Relat Dis. 2010 Jul 29.

Ratcliff MB, Reiter-Purtill J, Inge TH, Zeller MH. Changes in depressive symptoms among adolescent bariatric candidates from preoperative psychological evaluation to immediately before surgery. Surg Obes Relat Dis. 2011 Jan-Feb;7(1):50-4.

Inge TH, Xanthakos S. Sleeve gastrectomy for childhood morbid obesity: why not? Obes Surg. 2010 Jan;20(1):118-20.

Miyano G, Kalra M, Inge TH. Adolescent paraplegia, morbid obesity, and pickwickian syndrome: outcome of gastric bypass surgery. J Pediatr Surg. 2009 Mar;44(3):e41-4.

Zeller MH, Modi AC, Noll JG, Long JD, Inge TH. Psychosocial functioning improves following adolescent bariatric surgery. Obesity (Silver Spring). 2009 May;17(5):985-90.

Modi AC, Loux TJ, Bell SK, Harmon CM, Inge TH, Zeller MH. Weight-specific health-related quality of life in adolescents with extreme obesity. Obesity (Silver Spring). 2008 Oct;16(10):2266-71.

Ippisch HM, Inge TH, Daniels SR, Wang B, Khoury PR, Witt SA, Glascock BJ, Garcia VF, Kimball TR. Reversibility of cardiac abnormalities in morbidly obese adolescents. J Am Coll Cardiol. 2008 Apr 8;51(14):1342-8.

Inge TH. Childhood obesity--a problem of surgical proportions? Nat Clin Pract Gastroenterol Hepatol. 2008 Apr;5(4):180-1.

Grants

Adolescent Bariatrics-- Assessing Health Benefits & Risks (Administrative Supplement to fund additional research on risk taking behaviors). Co-Investigator. National Institutes of Health, National Institute of Drug Abuse: Administrative Supplement for Drug Abuse Research. Jul 2009 - Mar 2011. #1U01DK072493-01.

Administrative Supplement for Drug Abuse Research; Adolescent Bariatrics-- Assessing Health Benefits & Risks (Administrative Supplement to fund additional research on Obstructive Sleep Apnea). Principal Investigator. National Institute of Drug Abuse. Sept 2009 - Sept 2011. #1U01DK072493-01.

Sundeep G. Keswani, MD
Pediatric Surgeon, Division of General, Thoracic and Fetal Surgery

513-636-4371

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Sundeep G. Keswani, MD

Pediatric Surgeon, Division of General, Thoracic and Fetal Surgery

Fetal Surgeon, Fetal Care Center of Cincinnati

Assistant Professor, Division of Pediatric Surgery

Phone: 513-636-4371

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Specialties

Gene therapy applications; bone marrow contribution to tissue repair; fetal diagnosis and treatment

Education and Training

BA: University of Colorado, Boulder, CO, 1994.

MD: Ross University School of Medicine, 2000.

Residency: Louisiana State University Health Sciences Center, New Orleans, LA, 2000-2007.

Fellowship: The Children's Institute for Surgical Science, The Children's Hospital of Philadelphia & The Hospital of the University of Pennsylvania, Philadelphia, PA, 2002-2004.

Fellowship: Postdoctoral Research Fellow, The Center for Molecular Fetal Therapy, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2004.

Fellowship: Pediatric Surgery Fellowship, St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, MO, 2007-2009.

Licensure: American Board of Surgery Certified; Louisiana State Medical Licensure, active ; Missouri State Medical Licensure, active; Ohio State Medical Licensure, active; Indiana State Medical Licensure, active

Publications

View PubMed Publications

Bischoff A, Gupta A, D'Mello S, Mezoff A, Podberesky D, Barnett S, Keswani S, Frischer JS. Crohn's disease limited to the appendix: a case report in a pediatric patient. Pediatr Surg Int. 2010 Nov;26(11):1125-8.

Morris LM, Klanke CA, Lang SA, Pokall S, Maldonado AR, Vuletin JF, Alaee D, Keswani SG, Lim FY, Crombleholme TM. Characterization of endothelial progenitor cells mobilization following cutaneous wounding. Wound Repair Regen. 2010 Jul-Aug;18(4):383-90.

Katz AB, Keswani SG, Habli M, Lim FY, Zoltick PW, Midrio P, Kozin ED, Herlyn M, Crombleholme TM. Placental gene transfer: transgene screening in mice for trophic effects on the placenta. Am J Obstet Gynecol. 2009 Nov;201(5):499.e1-8

Vachharajani AJ, Rao R, Keswani S, Mathur AM. Outcomes of exomphalos: an institutional experience. Pediatr Surg Int. 2009 Feb;25(2):139-44.

Khan AR, Morris LM, Keswani SG, Khan IR, Le L, Lee WC, Hunt JP. Tuberculous peritonitis: a surgical dilemma. South Med J. 2009 Jan;102(1):94-5.

Bucher BT, Seigel J, Rosenblum E, Nesslein C, Keswani SG, Foglia R, Dillon P, Warner BW and Keller MS. A pediatric ambulatory wound service (PAWS): A novel approach in wound management. J Ped Surg 2009.

Gordon A, Kozin ED, Keswani SG, Vaikunth SS, Katz AB, Zoltick PW, Favata M, Radu AP, Soslowsky LJ, Herlyn M, Crombleholme TM. Permissive environment in postnatal wounds induced by adenoviral-mediated overexpression of the anti-inflammatory cytokine interleukin-10 prevents scar formation. Wound Repair Regen. 2008 Jan-Feb;16(1):70-9.

Parvadia JK, Keswani SG, Vaikunth S, Maldonado AR, Marwan A, Stehr W, Erwin C, Uzvolgyi E, Warner BW, Yamano S, Taichman N, Crombleholme TM. Role of VEGF in small bowel adaptation after resection: the adaptive response is angiogenesis dependent. Am J Physiol Gastrointest Liver Physiol. 2007 Sep;293(3):G591-8.

Keswani SG, Javazon EH, Badillo AT, Crombleholme TM, Zoltick PW, Radu AP, Kozin ED, Beggs K, Malik AA, Flake AW. Enhanced epithelial gap closure and increased angiogenesis in wounds of diabetic mice treated with adult murine bone marrow stromal progenitor cells. Wound Repair Regen. 2007 May-Jun;15(3):350-9.

Marc A. Levitt, MD
Director, Colorectal Center

513-636-3240

marc.levitt@cchmc.org

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Marc A. Levitt, MD

Director, Colorectal Center

Professor, Division of Pediatric Surgery

Phone: 513-636-3240

Fax: 513-636-3248

Email: marc.levitt@cchmc.org

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Specialties

Pediatric colorectal surgery; pediatric minimally invasive surgery

Biography

Dr. Levitt is the director of the Colorectal Center for Children at Cincinnati Children's Hospital Medical Center. He joined the full-time staff at Cincinnati Children's Hospital Medical Center in June 2005 when he and Dr. Peña were recruited to create the world’s first and only multidisciplinary and comprehensive Colorectal Center for Children.

Dr. Levitt received his undergraduate degree from the University of Pennsylvania, and his medical degree from the Albert Einstein College of Medicine, where he was elected to the Alpha Omega Alpha Society and worked with Dr. Peña as a medical student in 1992. Dr. Levitt completed his general surgery residency at the Mount Sinai Medical Center in New York and also served as a clinical and research fellow in pediatric colorectal surgery with Dr. Peña at Schneider Children's Hospital. He completed his pediatric surgery fellowship at the Children's Hospital of Buffalo, and was a pediatric surgical attending there, serving as the clinical director of their Pediatric Miniature Access Surgery Center, from 1999 to 2002. He was faculty at the Albert Einstein College of Medicine and Pediatric Surgeon at Schneider Children’s Hospital, North Shore Long Island Jewish Health System from 2002 to 2005.

Education and Training

MD: Albert Einstein College of Medicine.

Residency: Surgery, Mount Sinai Medical Center, New York.

Fellowhip: Pediatric Surgery, Children's Hospital of Buffalo.

Certification: Surgery; Pediatric Surgery.

Publications

View PubMed Publications

Bischoff A, Calvo-Garcia MA, Baregamian N, Levitt MA, Lim FY, Hall J, Peña A. Prenatal Counseling for Cloaca and Cloacal Exstrophy – Challenges faced by Pediatric Surgeons. Pediatr Surg Intl. 2012.

Livingston JC, Elicevik M, Breech L, Crombleholme TM, Peña A, Levitt MA. Persistent Cloaca: A 10-Year Review of Prenatal Diagnosis. Journal of Ultrasound in Medicine. 2012.

Hamrick M, Eradi B, Bischoff A, Louden E, Peña A, Levitt MA. Rectal Atresia and Stenosis; Unique Anorectal Malformations. J Pediatr Surg. 2012;47(6): 1280-4.

Chatoorgoon K, Peña A, Lawal TA, Louden E, Levitt MA. The Problematic Duhamel Pouch in Hirschsprung’s Disease: Manifestations and Treatment. European Journal of Pediatric Surgery. 2011;21: 366-9.

Bischoff A, Levitt MA, Peña A. Total Colonic Aganglionosis – A Surgical Challenge: How to Avoid Complications. Pediatr Surg Int. 2011 Oct;27(10): 1047-52.

Podberesky DJ, Weaver NC, Anton CG, Lawal T, Hamrick MC, Alam S, Peña A, Levitt MA. MRI of Acquired Posterior Urethral Diverticulum Following Surgery for Anorectal Malformations. Pediatr Radiol. 2011 Sept;41(9): 1139-1145.

Rangel SJ, Lawal TA, Bischoff A, Chatoorgoon K, Louden E, Peña A, Levitt MA. The Appendix as a Conduit for Antegrade Continence Enemas in Patients with Anorectal Malformations: Lessons Learned from 163 Cases treated over 18 years. J Pediatr Surg. 2011 Jun;46(6): 1236-42.

Alam S, Lawal TA, Peña A, Sheldon C, Levitt MA. Acquired Posterior Urethral Diverticulum Following Surgery for Anorectal Malformations. 2010 Jun;J Pediatr Surg. 46(6): 1231-5.

Chatoorgoon K, Peña A, Lawal TA, Hamrick M, Louden E, Levitt MA. Neoappendicostomy in the Management of Pediatric Fecal Incontinence. J Pediatr Surg. 2011 Jun;46(6): 1243-49.

Bischoff A, Levitt MA, Peña A. Laparoscopy and its use in the Repair of Anorectal Malformations. J Pediatr Surg. 2011;46(8): 1609-17.

Foong-Yen Lim, MD
Surgical Director, Fetal Care Center of Cincinnati

513-636-4371

foong.yen.lim@cchmc.org

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Foong-Yen Lim, MD

Surgical Director, Fetal Care Center of Cincinnati

Assistant Professor, UC Department of Surgery

Phone: 513-636-4371

Email: foong.yen.lim@cchmc.org

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Specialties

Open fetal surgery and fetoscopic surgery; ex-utero intrapartum treatment (EXIT); congenital high airway obstruction syndrome (CHAOS); congenital diaphragmatic hernia (CDH); fetal gene therapy; neonatal surgery; thoracic surgery; minimally invasive surgery

Education and Training

Pediatric Surgery Fellowship: The Children's Hospital of Philadelphia, 2004 – 2006.

General Surgery Residency: Penn State Milton S. Hershey Medical Center, 2002-2004.

Pediatric Surgery Research Fellowship and Fetal Surgery Fellowship: The Children's Hospital of Philadelphia, 2000-2002.

General Surgery Residency: Penn State Milton S. Hershey Medical Center, 1997-2000.

MD: Medical University of South Carolina, Charleston, SC, 1993 – 1997.

BS: Graceland College, Lamoni, Iowa, 1989 – 1993.

Publications

View PubMed Publications

Keswani SG, Le LD, Morris LM, Lim FY, Katz AB, Ghobril N, Habli M, Frischer JS, Crombleholme TM. Submucosal gland development in the human fetal trachea xenograft model: implications for fetal gene therapy. J Pediatr Surg. 2011 Jan;46(1):33-8.

Guimaraes CV, Kline-Fath BM, Linam LE, Calvo Garcia MA, Rubio EI, Lim FY. MRI findings in multifetal pregnancies complicated by twin reversed arterial perfusion sequence (TRAP). Pediatr Radiol. 2010 Dec 22.

Bischoff A, Levitt MA, Lim FY, Guimarães C, Peña A. Prenatal diagnosis of cloacal malformations. Pediatr Surg Int. 2010 Nov;26(11):1071-5.

Crombleholme TM, Lim FY, Habli M, Polzin W, Jaekle R, Michelfelder E, Cnota J, Liu C, Kim MO. Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation. Am J Obstet Gynecol. 2010 Oct;203(4):397.e1-9.

Habli M, Cnota J, Michelfelder E, Salisbury S, Schnell B, Polzin W, Lim FY, Crombleholme TM. The relationship between amniotic fluid levels of brain-type natriuretic peptide and recipient cardiomyopathy in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2010 Oct;203(4):404.e1-7.

Morris LM, Klanke CA, Lang SA, Pokall S, Maldonado AR, Vuletin JF, Alaee D, Keswani SG, Lim FY, Crombleholme TM. Characterization of endothelial progenitor cells mobilization following cutaneous wounding. Wound Repair Regen. 2010 Jul-Aug;18(4):383-90.

Vuletin JF, Lim FY, Cnota J, Kline-Fath B, Salisbury S, Haberman B, Kingma P, Frischer J, Crombleholme T. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. J Pediatr Surg. 2010 Apr;45(4):703-8.

Morris LM, Klanke CA, Lang SA, Lim FY, Crombleholme TM. TdTomato and EGFP identification in histological sections: insight and alternatives. Biotech Histochem. 2010 Dec;85(6):379-87.

Vaikunth SS, Morris LM, Polzin W, Gottliebson W, Lim FY, Kline-Faith B, Crombleholme TM. Congenital high airway obstruction syndrome due to complete tracheal agenesis: an accident of nature with clues for tracheal development and lessons in management. Fetal Diagn Ther. 2009;26(2):93-7.

Habli M, Bombrys A, Lewis D, Lim FY, Polzin W, Maxwell R, Crombleholme T. Incidence of complications in twin-twin transfusion syndrome after selective fetoscopic laser photocoagulation: a single-center experience. Am J Obstet Gynecol. 2009 Oct;201(4):417.e1-7.

Jaimie D. Nathan, MD
Surgical Director, Intestinal Transplant Program

513-636-4371

jaimie.nathan@cchmc.org

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Jaimie D. Nathan, MD

Surgical Director, Intestinal Transplant Program

Assistant Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: jaimie.nathan@cchmc.org

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Specialties

Hepatobiliary and pancreatic disease; liver, kidney, and intestinal transplantation; pediatric surgical oncology; neonatal surgery; minimally invasive surgery

Education and Training

BS: Yale University, New Haven, CT, 1993.

MD: Yale University, New Haven, CT, 1998.

Residency: General Surgery, Duke University Medical Center, Durham, NC, 1998-2000 and 2002-2005.

Surgical Research Fellowship: Duke University Medical Center, Durham, NC, 2000-2002.

Pediatric Surgery Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2005-2007.

Transplant Surgery Fellowship: University of Cincinnati, Cincinnati, OH, 2007-2009.

Certification: American Board of Surgery, General Surgery, 2007; American Board of Surgery, Pediatric Surgery, 2008; American Society of Transplant Surgeons Certification, 2009.

Publications

View PubMed Publications

Prada CE, Kaul A, Hopkin RJ, Page KI, Nathan JD, Bartholomew DW, Cohen MB, Heubi JE, Leslie ND, Burrow TA. Recurrent pancreatitis in ornithine transcarbamylase deficiency. Mol Genet Metab. 2012 Aug;106(4):482-484.

Bondoc AJ, Taylor JA, Alonso MH, Nathan JD, Wang Y, Balistreri WF, Bezerra JA, Ryckman FC, Tiao GM. The beneficial impact of revision of Kasai portoenterostomy for biliary atresia: an institutional study. Ann Surg. 2012 Mar;255(3):570-576.

Shin CR, Nathan J, Alonso M, Yazigi N, Kocoshis S, Tiao G, Davies SM. Incidence of acute and chronic graft-versus-host disease and donor T-cell chimerism after small bowel or combined organ transplantation. J Pediatr Surg. 2011 Sep;46(9):1732-1738.

Vigna SR, Shahid RA, Nathan JD, McVey DC, Liddle RA. Leukotriene B4 mediates inflammation via TRPV1 in duct obstruction-induced pancreatitis in rats. Pancreas. 2011 Jul;40(5):708-714.

Nathan JD, Romac J, Peng RY, Peyton M, Rockey DC, Liddle RA. Protection against chronic pancreatitis and pancreatic fibrosis in mice overexpressing pancreatic secretory trypsin inhibitor. Pancreas. 2010 Jan;39(1):e24-30.

Ryckman FC, Bucuvalas JC, Nathan J, Alonso M, Tiao G, Balistreri WF. Outcomes following liver transplantation. Semin Pediatr Surg. 2008 May;17(2):123-30.

Follmar KE, Condron SA, Turner II, Nathan JD, Ludwig KA. Treatment of metronidazole-refractory Clostridium difficile enteritis with vancomycin. Surg Infect. 2008 9:195-200.

Nathan JD, Rudolph JA, Kocoshis SA, Alonso MH, Ryckman FC, Tiao GM. Isolated liver and multivisceral transplantation for total parenteral nutrition-related end-stage liver disease. J Pediatr Surg. 2007 Jan;42(1):143-7.

Patel MB, Nathan JD, Frush DP, Rice HE. Nonoperative management of asymptomatic traumatic pulmonary hernia in a young child. J Trauma. 2007 62:234-235.

Nathan JD, Romac J, Peng RY, Peyton M, MacDonald RJ, Liddle RA. Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice. Gastroenterology. 2005 128:717-727.

Alberto Peña, MD
Founding Director, Colorectal Center

513-636-3240

alberto.pena@cchmc.org

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Alberto Pena, MD

Founding Director, Colorectal Center

Professor, Division of Pediatric Surgery

Phone: 513-636-3240

Fax: 513-636-3248

Email: alberto.pena@cchmc.org

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Specialties

Clinical research regarding colorectal problems in children

Biography

Alberto Peña, MD, director of the Colorectal Center, at Cincinnati Children's, received his medical degree at the Military Medical School in Mexico City, in 1962.

Dr. Peña trained in general surgery and medical pediatrics at the Central Military Hospital, finishing in 1968. From 1969 until December 1971, he trained at Boston Children's Hospital.

Dr. Peña moved back to Mexico City as the surgeon-in-chief of the National Institute of Pediatrics from January 1972 until June 1985.

Dr. Peña joined the full-time staff at Schneider Children's Hospital in July 1985 and was the chief of Pediatric Surgery and professor of Surgery at the Albert Einstein College of Surgeons.

In 1982, Dr. Peña described a new approach for the management of anorectal malformations: Posterior Sagittal Anoplasty / PSARP, also known as the Pull-Through Procedure.

Since 1982 until the present, Dr. Peña has been traveling all over the world, lecturing and operating on children affected by this particular malformation.

At the present time, Dr. Peña dedicates 80 percent of his time to the treatment of anorectal problems in children.

Seventy percent of the patients operated on by Dr. Peña at Cincinnati Children's come from other states and from all over the world.

Education and Training

MD: Military Medical School, Mexico City, Mexico, 1962.

Residency: Central Military Hospital, Mexico City, Mexico, 1966; Children's Hospital Medical Center, Boston, MA, 1969-1971.

Publications

View PubMed Publications

Lawal TA, Rangel SJ, Bischoff A, Peña A, Levitt MA. Laparoscopic-Assisted Malone Appendicostomy in the Management of Fecal Incontinence in Children. J Laparoendosc Adv Surg Tech A. 2011 Mar 2.

Lawal TA, Chatoorgoon K, Collins MH, Coe A, Peña A, Levitt MA. Redo pull-through in Hirschsprung's disease for obstructive symptoms due to residual aganglionosis and transition zone bowel. J Pediatr Surg. 2011 Feb;46(2):342-7.

Bischoff A, Levitt MA, Lim FY, Guimarães C, Peña A. Prenatal diagnosis of cloacal malformations. Pediatr Surg Int. 2010 Nov;26(11):1071-5.

Bischoff A, Levitt MA, Lawal TA, Peña A. Colostomy closure: how to avoid complications. Pediatr Surg Int. 2010 Nov;26(11):1087-92.

Bischoff A, Levitt MA, Breech L, Louden E, Peña A. Hydrocolpos in cloacal malformations. J Pediatr Surg. 2010 Jun;45(6):1241-5.

Peña A, Bischoff A, Breech L, Louden E, Levitt MA. Posterior cloaca--further experience and guidelines for the treatment of an unusual anorectal malformation. J Pediatr Surg. 2010 Jun;45(6):1234-40.

Levitt MA, Kant A, Peña A. The morbidity of constipation in patients with anorectal malformations. J Pediatr Surg. 2010 Jun;45(6):1228-33.

Levitt MA, Peña A. Minimally invasive treatment of fecal incontinence and constipation in children. Minerva Chir. 2010 Apr;65(2):223-34. Review.

Levitt MA, Dickie B, Peña A. Evaluation and treatment of the patient with Hirschsprung disease who is not doing well after a pull-through procedure. Semin Pediatr Surg. 2010 May;19(2):146-53.

Levitt MA, Peña A. Cloacal malformations: lessons learned from 490 cases. Semin Pediatr Surg. 2010 May;19(2):128-38.

Frederick C. Ryckman, MD
Professor of Surgery / Transplantation

513-636-4371

frederick.ryckman@cchmc.org

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Frederick C. Ryckman, MD

Professor of Surgery / Transplantation

Sr. Vice President - Medical Operations

Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: frederick.ryckman@cchmc.org

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Specialties

Transplantation; liver; kidney transplantation; small intestine; biliary disease; Extracorporeal membrane oxygenation (ECMO); minimally invasive surgery; chest wall abnormalities

Biography

Frederick C. Ryckman, MD, is clinical director of the Pediatric General and Thoracic Surgery Division.

Dr. Ryckman is also vice president of System Capacity & Perioperative Operations.

Dr. Ryckman is also a pediatric surgeon at the Fetal Care Center of Cincinnati.

Education and Training

BS: Lyman Briggs College of Science and Mathematics, Michigan State University, East Lansing, MI, 1969 to 1973.

MD: University of Michigan Medical School, Ann Arbor, MI, 1977.

Residency: University of Florida Medical Center, Gainesville, FL, 1977 to 1982.

Fellowship: Pediatric Surgery, Children's Hospital Medical Center, Cincinnati, OH, 1982 to 1984.

Certification: National Board of Medical Examiners, 1977; American Board of Surgery, 1983; recertification, 1993; Certificate of Special Competence in Pediatric Surgery, 1986; recertification, 1993.

Publications

View PubMed Publications

Wagner LM, Gelfand MJ, Laor T, Ryckman FC, Al-Ghawi H, Bove KE. A Welcome Surprise: Nodular Fasciitis Presenting as Soft Tissue Sarcoma. J Pediatr Hematol Oncol. 2010 Oct 21.

Taylor JA, Ryckman FC. Management of small bowel volvulus around feeding Roux-en-Y limbs. Pediatr Surg Int. 2010 Apr;26(4):439-42.

Ryckman FC, Yelton PA, Anneken AM, Kiessling PE, Schoettker PJ, Kotagal UR. Redesigning intensive care unit flow using variability management to improve access and safety. Jt Comm J Qual Patient Saf. 2009 Nov;35(11):535-43.

Rattan AS, Laor T, Ryckman FC, Brody AS. Pectus excavatum imaging: enough but not too much. Pediatr Radiol. 2010 Feb;40(2):168-72.

Propst EJ, Lin EP, Istaphanous GK, Boesch RP, Ryckman FC, Cotton RT, Rutter MJ. Management of traumatic tracheobronchial separation in a teenager using a fabricated extra-long endotracheal tube. Int J Pediatr Otorhinolaryngol. 2009 Aug;73(8):1163-7.

Ryckman FC, Schoettker PJ, Hays KR, Connelly BL, Blacklidge RL, Bedinghaus CA, Sorter ML, Friend LC, Kotagal UR. Reducing surgical site infections at a pediatric academic medical center. Jt Comm J Qual Patient Saf. 2009 Apr;35(4):192-8.

Dickie B, Dasgupta R, Nair R, Alonso MH, Ryckman FC, Tiao GM, Adams DM, Azizkhan RG. Spectrum of hepatic hemangiomas: management and outcome. J Pediatr Surg. 2009 Jan;44(1):125-33.

Ryckman FC, Bucuvalas JC, Nathan J, Alonso M, Tiao G, Balistreri WF. Outcomes following liver transplantation. Semin Pediatr Surg. 2008 May;17(2):123-30.

Sparling KW, Ryckman FC, Schoettker PJ, Byczkowski TL, Helpling A, Mandel K, Panchanathan A, Kotagal UR. Financial impact of failing to prevent surgical site infections. Qual Manag Health Care. 2007 Jul-Sep;16(3):219-25.

Greg M. Tiao, MD
Surgical Director, Liver Transplantation

513-636-4371

greg.tiao@cchmc.org

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Greg M. Tiao, MD

Surgical Director, Liver Transplantation

Director, Small Bowel Program

Associate Director, Pediatric Surgery Training Program

Pediatric Surgeon

Associate Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: greg.tiao@cchmc.org

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Specialties

Biliary atresia

Biography

As a pediatric surgeon and a transplant surgeon, Dr. Tiao is involved in the care of children afflicted with biliary atresia from the time of presentation and diagnosis to the initial Kasai portoenterostomy to the liver transplant, when necessary. He sees the many challenges children and their families experience when diagnosed with this life threatening disease process. From that perspective, defining the basis of this disease process such that therapeutic strategies can be developed eliminating these complex interventions is his career goal. His short term goal is to develop an independent research laboratory investigating the pathogenesis of virus induced biliary atresia specifically seeking to determine the mechanistic basis of this disease so that new treatment strategies can be developed to salvage the native liver.

Dr. Tiao's overarching hypothesis is that biliary atresia results from the infection of cholangiocytes by a virus triggering immune-mediated biliary obstruction. His focus is to determine the mechanisms used by RRV to infect cholangiocytes, how RRV undergoes replication within the cholangiocyte, and how infected cholangiocytes modify the microenvironment, activating the immune system resulting in biliary obstruction. Determination of the mechanistic basis of these inter-related events is essential to understanding the pathogenesis of virus induced BA. By focusing on the basis for the viral insult in the initiation of biliary atresia, he has defined an area of independence from Dr Jorge Bezerra, his primary research mentor.

Education and Training

BS: Northwestern University, Evanston, IL, 1986.

MD: University of Illinois, Chicago, IL, 1990.

Residency: Loyola University, Maywood, IL, 1991-1992; Senior Resident, Department of Surgery, University of Cincinnati, Cincinnati, OH, 1995-1997;Chief Resident, Department of Surgery, University of Cincinnati, Cincinnati, OH, 1997-1998.

Fellowships: Research Fellow, University of Cincinnati, Cincinnati, OH, 1992-1995; Transplant Surgery Fellow, University of Cincinnati, Cincinnati, OH, 2000-2002;Pediatric Surgery Fellow, Los Angeles Children's Hospital, Los Angeles, CA, 1998-2000.

Certification: Pediatric Surgeon, 2000; Transplant Surgeon, 2002.

Publications

Coots A, Donnelly B, Mohanty S, Tiao G. Rotavirus Infection of Human Cholangiocytes Parallels the Murine Model of Biliary Atresia. Journal of Surgical Research. Epub ahead of print. 2012.

Meyers RL, Tiao GM, Dunn SP, Langham Jr, MR. Liver transplantation in the management of unresectable hepatoblastoma in children. Frontiers in Bioscience. 2012 Jan;E4:1293-1302.

Fernandez KS, Baum R, Fung B, Yeager N, Leonis MA, Wagner LM, Tiao G, Ross ME. Chemoresistant Hepatoblastoma in a Patient with Mosaic Trisomy 18 Treated with Orthotopic Liver Transplantation. Peditr Blood Cancer. 2011;56:498-500.

Superina R, Magee J, Brandt M, Healey P, Tiao G, Ryckman F, Karrer F, Iyer K, Fecteau A, West K, Burns R, Flake A, Hammin L, Lowell J, Dillon P, Columbani P, Ricketts R, Yun L, Moore J, Kasper W. Childhood Liver Research and Education Network. AnnSurg. 2011.

Bondoc A, Taylor J, Alonso M, Nathan, J, Wang Y, Balistreri W, Bezerra J, Ryckman F, Tiao G. The Beneficial Impact of Revision of Kasai Portoenterostomy for Biliary Atresia: An Institutional Study. AnnSurg. 2012;255(3):570-6.

Wang W, Donnelly B, Bondoc A, Mohanty SK, McNeal M, Ward R, Sestak K, Zheng S, Tiao G. The rhesus rotavirus gene encoding VP4 is a major determinant in the pathogenesis of biliary atresia in newborn mice. J Virol. 2011 Jun.

Jafri M, Donnelly B, Bondoc A, Allen S, Tiao G. Cholangiocyte secretion of chemokines in experimental biliary atresia. J Pediatr Surg. 2009;44(3):500-7.

Bondoc AJ, Jafri MA, Donnelly B, Mohanty SK, McNeal MM, Ward, RL, Tiao GM. Prevention of the murine model of biliary atresia after live rotavirus vaccination of dams. J Pediatr Surg. 2009;44(8):1479-90.

Grants

The Molecular Determinants of Virus Induced Biliary Induced Biliary Asteria. Principal Investigator. Apr 2011 - Mar 2016.

Nycomed Liver Trial. Principal Investigator. 2012 - present. TC-2402-040-SP.

Daniel von Allmen, MD
Director, Division of General and Thoracic Surgery

513-636-4371

daniel.vonallmen@cchmc.org

Daniel von Allmen, MD

Director, Division of General and Thoracic Surgery

Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Email: daniel.vonallmen@cchmc.org

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Specialties

Clinical Interests

Pediatric surgical oncology; pediatric inflammatory bowel disease; surgical innovation; surgical robotics

Research Interests

Oncology; innovation; surgical workforce

Biography

Daniel von Allmen, MD, comes to Cincinnati from Chapel Hill, NC where he was the Surgeon-in-Chief and Division Chief at the North Carolina Children’s Hospital.

Dr. von Allmen completed his general surgery training at the University of Cincinnati and Cincinnati Children’s Hospital Medical Center. He is currently the Program Committee chair of the American Pediatric Surgical Association. He also serves on the Program Committee for the American Academy of Pediatrics Surgical Section and is a member of the Steering Committee for the Surgical Section of the Children’s Oncology Group.

Dr. von Allmen's special clinical interests include pediatric surgical oncology, pediatric inflammatory bowel disease, surgical innovation, and surgical robotics.

Education and Training

MD: University of Vermont College of Medicine.

Residency: General Surgery, University of Cincinnati, Cincinnati, OH.

Fellowship: Pediatric Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Certifications: General Surgery, Pediatric Surgery.