Conditions Treated
The Division of Allergy and Immunology at Cincinnati Children's Hospital Medical Center offers consultation, treatment and diagnostic testing for children with allergic disorders, including:
- Allergic conjunctivitis
- Allergic rhinitis
- Asthma
- Drug allergies
- Eosinophilic disorders, including
- Eosinophilic colitis
- Eosinophilic enteritis
- Eosinophilic esophagitis
- Eosinophilic gastroenteritis
- Hypereosinophilic syndrome
Food allergy Hives and angioedema Insect sting allergy Latex allergy Primary immune deficiency, including: T-cell immune deficiency Combined immune deficiency DiGeorge syndrome Severe combined immune deficiency (SCID) Wiskott-Aldrich syndromeB-cell immune deficiency Common variable immunodeficiency Hyper IgM syndrome IgA deficiency Specific antibody deficiency X-linked agammaglobulinemiaGranulocyte deficiency Chediak Higashi syndrome Chronic granulomatous disease (CGD) Hyper IgE syndrome Leukocyte adhesion defect (LAD)Children with suspected immunodeficiency are also evaluated. Immunologic evaluation includes:
- Detailed evaluation of cellular immunity
- Lymphocyte phenotyping, enumeration, and activation markers
- T- cell mitogen and antigen reposes
- Cytotoxic T lymphocyte function
- Natural killer cell function
Evaluation of antibody function Antibody levels — IgG, IgA, IgM, IgE, IgG subclasses Specific antibody responses to vaccines or pathogens Complement levels and functionEvaluation of granulocyte morphology and function Adhesion, phagocytosis, killing Respiratory burstClose collaboration with the Cincinnati Children's Divisions of Gastroenterology, Hepatology and Nutrition and Hematology / Oncology ensures the provision of comprehensive clinical care to patients and their families. Faculty are active in clinical studies, as well as laboraotory investigation of allergic disorders.
