Marc E. Rothenberg, MD, PhD
Title
Director Allergy and Immunology
Appointment
Professor of Pediatrics, University of Cincinnati College of Medicine
Email
marc.rothenberg@cchmc.org
Phone
513-636-7210
Fax
513-636-3310
Bio
Marc E. Rothenberg, MD, PhD, is the Director of the Division of Allergy and Immunology at Cincinnati Children's Hospital Medical Center, and a tenured Professor of Pediatrics at Cincinnati Children’s and the University of Cincinnati College of Medicine. He graduated summa cum laude with Highest Honors in Chemistry and Biochemistry from Brandeis University. He then matriculated at Harvard Medical School in the combined MD / PhD program. His PhD under the mentorship of Dr. Frank Austen included seminal studies on eosinophil hematopoiesis, as he developed the first culture system for human eosinophils. After completing a two-year residency in pediatrics at Children’s Hospital in Boston, Dr. Rothenberg did a combined fellowship in allergy / immunology and hematology at Children’s Hospital in Boston. During this fellowship program, Dr. Rothenberg did post-doctorate training in the genetics laboratory of Dr. Philip Leder at Harvard Medical School, where he cloned the eotaxin chemokine. After being on faculty of Harvard Medical School for one year, he came to the University of Cincinnati and Cincinnati Children's, one of the largest pediatric medical and research centers in the United States. He is actively involved in managing a research program focused on understanding the molecular mechanisms of allergic disorders. At Cincinnati Children’s, he has helped build a top program in pediatric research, and his division is a leader in pediatric allergy and immunology. In addition, he sees patients suffering from allergic and immunological diseases from around the world as part of the Cincinnati Center for Eosinophilic Disorders that he directs.
Dr. Rothenberg’s awards include the Pharmacia Allergy Research Foundation Award for the best young investigator in the allergy field; the Young Investigator Award and the Scholar in Allergy Award from the American Academy of Allergy, Asthma, and Immunology; the Ohio Governor’s Recognition Award; and the 2007 E Mead Johnson Award from the Society of Pediatric Research. He is an elected member of the American Society of Clinical Investigation, Society for Pediatric Research, and a Diplomate of the American Academy of Allergy, Asthma and Immunology. Among his extensive publications of over 150 articles on molecular mechanisms of allergic responses, Dr. Rothenberg edited a book entitled, “Chemokines in Allergic Disease”. He has served on various review panels for journals and grant agencies including the National Institutes of Health, Burroughs Trust, and the Medical Research Council of the UK. He is a current member of the Advisory Council of the NIAID. His research has been supported by numerous sources including the Human Frontier Science Program Organization, the Burroughs Wellcome Fund and the National Institutes of Health.
Credentials
MD, PhD: Harvard Medical School, Cambridge, Mass., 1990.
Residency: Pediatrics, Children's Hospital, Boston, Mass., 1991-1992.
Fellowship: Immunology / Allergy, Children's Hospital, Boston, Mass., 1992-1994; Hematology / Oncology, Children's Hospital and Dana Farber Cancer Institute, Boston, Mass., 1992-1995.
Certification: National Board of Medical Examiners, 1991; Board of Registration in Medicine, MA, 1992; American Board of Pediatrics, 1995, 2001; Ohio State Medical Board, 1997; American Board of Allergy and Immunology, 1997; American Board of Pediatrics recertification, 2000.
Position History
Academic Appointments
- 1990-1991 Clinical Fellow in Pediatrics, Harvard Medical School
- 1992-1995 Research Fellow in Pediatrics, Harvard Medical School
- 1995-1996 Instructor of Pediatrics, Harvard Medical School
- 1996-1999 Assistant Professor of Pediatrics, University of Cincinnati College of Medicine
- 1996- Member, Graduate Program Molecular and Developmental Biology, University of Cincinnati College of Medicine
- 1998- Member, Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine
- 1998- Member, Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine
- 1999-2000 Associate Professor of Pediatrics, University of Cincinnati College of Medicine
- 2000-2002 Associate Professor of Pediatrics (tenured), University of Cincinnati College of Medicine
- 2001- Endowed Chair, Allergy and Immunology, Cincinnati Children's Hospital Research Foundation
- 2002- Professor of Pediatrics (tenured), University of Cincinnati College of Medicine
- 2002- Affiliate Faculty, Center for Epidemiology and Biostatistics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center
- 2004- Member, Graduate Program of Immunobiology, University of Cincinnati College of Medicine
Clinical Appointments
- 1990-1991 Intern in Pediatrics, Children's Hospital, Boston, Ma.
- 1991-1992 Resident in Pediatrics, Children's Hospital, Boston, Ma.
- 1992-1994 Immunology/Allergy Fellow, Children's Hospital, Boston,
- 1992-1995 Hematology/Oncology Fellow, Children's Hospital and Dana Farber Cancer Institute, Boston, Ma.
- 1995-1996 Senior Staff Physician, Children's Hospital, Boston, Ma.
- 1996- Staff Physician, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
- 1999-2001 Section Chief, Section of Allergy and Clinical Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
- 2001- Director, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
- 2005- Director, Cincinnati Center for Eosinophilic Disorders (CCED)
Awards and Honors
- Eastman Kodak Science and Engineering Regional Award, 1976
- National Honor Society, George W. Hewlett High School, 1979
- Phi beta kappa, Brandeis University, 1982
- Melvin N. Snyder Chemistry Award, Brandeis University, 1983
- Summa cum laude with highest honors in biochemistry and chemistry, Brandeis University, 1983
- Medical Scientist Training Program Award, Harvard Medical School, 1985
- Physician Scientist Training Program Award, Harvard Medical School, 1985
- Young Investigator Award, American Academy of Allergy and Immunology, 1988
- Scholar in Allergy Award, American Academy of Allergy and Immunology, 1993
- Pharmacia Allergy Research Foundation Annual Award, 1998
- Governor's Recognition Award, State of Ohio, 2002
- Best Doctors in America Award, 2003
- Awarded "2004 Best Doctors"
- Burton Zweimann Lectureship, American Academy of Allergy, Asthma, and Immunology, 2004
- Awarded "2005 Best Doctors"
- David A. Talmage Lectureship, Colorado Allergy Society, 2005
- E Mead Johnson Award, Society of Pediatric Research, 2007
- Best Doctors in America, 2008
Research
Eosinophils; chemokines
Research Grants and Contracts
Food Allergy and Anaphylaxis Network (FAAN), Epidemiology and molecular classification of eosinophilic esophagitis, 2005-2007, Principal Investigator.
National Institutes of Health, NIDDK, 1R01, Mechanistic analysis of eosinophilic esophagitis, 2005-2010, Co-Investigator.
Cincinnati Children's Translational Research Initiative, Eotaxin-3 in eosinophilic esophagitis, 2006-2007.
National Institutes of Health, NIAID Center Grant (Project 2), Epithelial-derived eotaxin 3 and eosinophilic esophagitis, 2006-2011, Co-Investigator.
Food Allergy and Anaphylaxis Network (FAAN), Molecular analysis of eosinophilic esophagitis, 2007-2009, Principal Investigator.
National Institutes of Health, NIAID, R01 DK076893-01, IL-13 and eosinophilic esophagitis, 2007-2012, Principal Investigator.
Dana Foundation, Novel Genetic and Therapeutic approaches focusing on siglec-8 for the diagnosis and treatment of human idiopathic eosinophilic disorders, 2007-2010, Principal Investigator.
Publications, Most Recent
View Marc Rothenberg's publications at Cincinnati Children's as listed by PubMed.
Pope SM, Fulkerson PC, Nikolaidis N, Blanchard C, Zimmermann N, Molkentin JD, Rothenberg ME. Identification of a cooperative mechanism involving IL-13 and eotaxin-2 in experimental allergic lung inflammation, J Biol Chem, 2005; 280:13952-61.
Fulkerson PC, Zhu H, Zimmermann N, Rothenberg ME. CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism, Blood, 2005;106:436-43.
Akei HS, Mishra A, Blanchard C, Rothenberg ME. Epicutaneous antigen exposure primes for eosinophilic esophagitis, Gastroenterology, 2005; 129:985-994.
Blanchard C, Mishra A, Saito-Akei H, Monk P, Anderson I, Rothenberg ME. Inhibition of human interleukin-13-induced respiratory and esophageal inflammation by anti-human-interleukin-13 antibody (CAT-354), Clin Exper Allergy, 2005; 35:1096-103.
Pope SM, Zimmermann N, Stringer KF, Karow ML, Rothenberg ME. The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia, J. Immunol, 2005; 175:5341-5350.
Blanchard C, Wang N. Mishra A, Fulkerson PC, Jameson SC, Kirby C, Konikoff MR, Collins MH, Cohen MB, Stringer KF, Akers R, Hogan SP, Assa'ad AH, Putnam PE, Aronow BJ, Rothenberg ME. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis, J Clin Invest, 2006; 116:536-547.
Yamada Y, Rothenberg ME, Lee AW, Akei HS, Brandt EB, Williams DA, Cancelas JA. The FIP1L1-PDGFR fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease, Blood, 2006; 107:4071-9.
Saito Akei H, Brant EB, Mishra A, Strait RT, Finkelman FD, Warrier MR, Hershey GKH, Blanchard C, Rothenberg ME. Epicutaneous aeroallergen exposure induces systemic Th2 immunity that predisposes to allergic nasal responses. J Allergy Clin Immunol, 2006; 118-62-9.
Hogan SP, Seidu L, Blanchard C, Groschwitz K, Mishra A, Karow ML, Ahrens R, Artis D, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rothenberg ME. Resistin-like molecule (RELM)- regulates innate colonic function: barrier integry and inflammation susceptibility, J Allergy Clin Immunol, 2006; 118:257-68.
DeBrosse CW, Case JW, Putnam PE, Collins ME, Rothenberg ME. Quantity and distribution of eosinophils in the gastrointestinal tract of children, Pediatr Dev Pathol, 2006; 9:210-218.
Rothenberg ME, Doepker MP, Lewkowich IP, Chiaramonte MG, Stringer K, Finkelman FD, MacLeod CL, Ellies L, Zimmermann N. The cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung, Proc Natl Acad Sci USA, 2006; 103:14895-14900.
Konikoff MR, Noel RJ, Blanchard C, Kirby C, Jameson SC, Buckmeier B, Akers R, Cohen MB, Collins MH, Assa'ad AH, Aceves SS, Putnam PE, Rothenberg ME. A randomized double-blind placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis, Gastroenterology, 2006;131:1381-1391. Epub 2006 Aug 16.
Konikoff MR, Blanchard C, Kirby C, Buckmeier B, Cohen MB, Heubi JE, Putnam PE, Rothenberg ME. Potential biomarkers of eosinophilic esophagitis, Clin Gastroenterol Hepatol, 2006; 4:1328-1336. Epub 2006 Oct 21.
Fulkerson PC, Fischetti CA, McBride ML, Hassman LM, Hogan SP, Rothenberg ME. A central regulatory role for eosinophils and the eotaxin-CCR3 axis in chronic experimental allergic airway inflammation, Proc Natl Acad Sci USA, 2006; 103:16418-23. Epub 2006 Oct 23.
Fulkerson PC, Fischetti CA, Rothenberg ME. Eosinophils and CCR3 regulate IL-13-transgene-induced pulmonary remodeling, Am J Pathol, 2006; 169:2117-2126.
Stein ML, Collins MH, Villanueva JM, Kushner JP, Putnam PE, Buckmeier, BK, Filipovich AH, Assa'ad AH, Rothenberg ME. Anti-interleukin-5 (mepolizumab) therapy for eosinophilic esophagitis, J Allergy Clin Immunol, 2006; 118:1312-1319.
Nikolaidis NM, Wang TC, Hogan SP, Rothenberg ME. Allergen induced TFF2 is expressed by mucus-producing airway epithelial cells but is not a major regulator of inflammatory responses in the murine lung, Exp Lung Res, 2006; 32:483-97.
Mishra A, Schlotman J, Wang M, Rothenberg ME. Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis, J Leukoc Biol, 2007; 81:916-24.
Assa’ad AH, Putnam PE, Collins MH, Akers RM, James SC, Kirby CL, Buckmeier BK, Bullock JZ, Collier AR, Konikoff MR, Noel RJ, Guajardo JR, Rothenberg ME. Pediatric patients with eosinophilic esophagitis: An eight-year follow up, J Allergy Clin Immunol, 2007; 119:731-8.
Bergeron C, Boulet LP, Page N, Laviolette M, Rothenberg ME, Hamid Q. Influence of cigarette smoke on arginine pathway in asthmatic airways, J Allergy Clin Immunol, 2007; 119:391-7.
McGraw DW, Elwing JM, Fogel KM, Wang WCH, Glinka CB, Mihlbachler KA, Rothenberg ME, Liggett SP. Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation, J Clin Invest, 2007; 117:1391-8.
Mishra A, Wang M, Schlotman J, Nikolaidis NM, DeBrosse CW, Karow ML, Rothenberg ME. Resistin-like molecule (RELM)-β is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung, Am J Physiol Lung Cell Mol Physiol, 2007; 293:L305-13.
Simson L, Dent LA, Matthaei KI, Rothenberg ME, Foster PS, Smyth MJ, Parish CR. Regulation of carcinogenesis by interleukin-5 and CCL11: A potential role for eosinophils in tumor immune surveillance, J Immunol, 2007; 178:4222-9.
Bullock JZ, Villanueva JM, Blanchard C, Filipovich AH, Putnam PE, Collins MH, Risma KA, Akers RM, Kirby CL, Buckmeier BK, Assa’ad AH, Hogan SP, Rothenberg ME. Interplay of adaptive Th2 immunity with eotaxin-3/C-C chemokine receptor 3 in eosinophilic esophagitis, J Pediatr Gastroenterol Nutr, 2007; 45:22-31.
Blanchard C, Mingler MK, Vicario M, Abonia JP, Wu YY, Lu TX, Collins MH, Putnam PE, Wells SI, Rothenberg ME. IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids, J Allergy Clin Immunol, 2007; 120:1292-300.
Furuta GT, Liacouras CA, Collins MH, Gupta SK, Justinich C, Putnam PE, Bonis P, Hassall E, Straumann A, Rothenberg ME; First International Gastrointestinal Eosinophil Research Symposium (FIGERS) Subcommittees. Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment, Gastroenterology, 2007; 133:1342-63.
Munitz A, Bachelet I, Finkelman FD, Rothenberg ME, Levi-Schaffer F. CD48 is critically involved in allergic eosinophilic airway inflammation, Am J Respir Crit Care Med, 2007; 175:911-8.
Rothenberg ME. Eosinophils in the new millennium, J Allergy Clin Immunol, 2007; 119:1321-2.
Rothenberg ME, Cohen MB. An eosinophil hypothesis for functional dyspepsia, Clin Gastroenterol Hepatol, 2007; 5:1147-8.
Zuo L, Rothenberg ME. Gastrointestinal eosinophilia, Immunol Allergy Clin North Am, 2007; 27:443-55.
Blanchard C, Rothenberg ME. Basic pathogenesis of eosinophilic esophagitis, Gastrointest Endosc Clin N Am, 2008; 18:133-43.
Mishra A, Wang M, Pemmaraju VR, Collins MH, Fulkerson PC, Abonia JP, Blanchard C, Putnam PE, Rothenberg ME. Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia, Gastroenterology, 2008; 134:204-14.
Hogan SP, Rothenberg ME. Dietary allergenic proteins and intestinal immunity: a shift from oral tolerance to sensitization, Clin Exp Allergy, 2008; 38:229-32.
Hogan SP, Rosenberg HF, Moqbel R, Phipps S, Foster PS, Lacy P, Kay AB, Rothenberg ME. Eosinophils: biological properties and role in health and disease, Clin Exp Allergy, 2008; 38:709-50.
Herbert DR, Orekov T, Perkins C, Rothenberg ME, Finkelman FD. IL-4R{alpha} Expression by Bone Marrow-Derived Cells Is Necessary and Sufficient for Host Protection against Acute Schistosomiasis, J Immunol, 2008; 180:4948-55.
Forbes EE, Groschwitz K, Abonia JP, Brandt EB, Cohen E, Blanchard C, Ahrens R, Seidu L, McKenzie A, Strait R, Finkelman FD, Foster PS, Matthaei KI, Rothenberg ME, Hogan SP. IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity, J Exp Med, 2008; 205:897-913.
Johnson TR, Rothenberg ME, Graham BS. Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein, J Leukoc Biol, 2008.
Rothenberg ME, Klion AD, Roufosse FE, Kahn JE, Weller PF, Simon HU, Schwartz LB, Rosenwasser LJ, Ring J, Griffin EF, Haig AE, Frewer PI, Parkin JM, Gleich GJ; Mepolizumab HES Study Group. Treatment of patients with the hypereosinophilic syndrome with mepolizumab, N Engl J Med, 2008; 358:1215-28.
Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME. Surfactant protein D alters allergic lung responses in mice and human subjects, J Allergy Clin Immunol, 2008; 121(5):1140-1147.
Stein ML, Villanueva JM, Buckmeier BK, Yamada Y, Filipovich AH, Assa'ad AH, Rothenberg ME. Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels, J Allergy Clin Immunol, 2008; 121(6):1473-83, 1483.
Rothenberg ME. 2007 E. Mead Johnson Award: Scientific Pursuit of the Allergy Problem, Pediatr Res, 2008; 64(1):110-5.
Munitz A, McBride ML, Bernstein JS, Rothenberg ME. A dual activation and inhibition role for the paired immunoglobulin-like receptor B (PIR-B) in eosinophils. Blood 2008;111(12):5694-703.
Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME. Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis, Proc Natl Acad Sci U S A, 2008; 105(20):7240-5.
Collins MH, Blanchard C, Abonia JP, Kirby C, Akers R, Wang N, Putnam PE, Jameson SC, Assa'ad AH, Konikoff MR, Stringer KF, Rothenberg ME. Clinical, Pathologic, and Molecular Characterization of Familial Eosinophilic Esophagitis Compared With Sporadic Cases, Clin Gastroenterol Hepatol, 2008; 6(6):621-9.
Yamada Y, Sanchez-Aguilera A, Brandt EB, McBride M, Al-Moamen NJ, Finkelman FD, Williams DA, Cancelas JA, Rothenberg ME. FIP1L1/PDGFRα synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome, Blood, 2008; 171.
Johnson TR, Rothenberg, ME, Graham BS. Pulmonary Eosinophilia Requires Interleukin-5, Exotaxin-1, and CD4+ T Cells in Mice Immunized with Respirator Syncytial Virus G Glycoprotein, J Leukoc Biol, 2008.
Blanchard C, Mingler MK, McBride M, Putman PE, Collins MH, Chang G, Stringer K, Anonia JP, Molkentin JD, Rothenberg ME. Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses, Mucosal Immunology, 2008; 1(4):289-96.
Professional Organization Memberships
- Massachusetts Medical Society, 1983-1996
- Physicians for Social Responsibility, 1983-1988
- American Association for the Advancement of Science, 1987-present
- American Academy of Pediatrics, 1990-present
- American Academy of Allergy, Asthma and Immunology, 1993-present
- American Association of Immunologists, 1998-present
- Pharmacia Allergy Research Foundation, 1998-present
- Society for Mucosal Immunology, 1998-present
- Society for Pediatric Research, 1998-present
- American Society of Clinical Investigation, 2000-present
- American Pediatric Society, 2000-present
- American Society for Biochemistry and Molecular Biology, 2005-present
- American College of Allergy, Asthma and Immunology, 2006-present
- American Association of Physicians, 2007- present
Books
Rothenberg ME, editor of Chemokines in Allergic Diseases, New York: Marcel Dekker, 2000.
Recent Book Chapters
Rothenberg ME. Eotaxin. In: Thomas E. Creighton, ed. The Encyclopedia of Molecular Medicine, John Wiley & Sons, Inc., New York, 2002; pp 1181-1185.
Zimmermann N, Rothenberg ME. Therapeutic Targeting of Chemokines and Chemokine Receptors. In: Agosti J, Sheffer AL, eds. Biotherapeutic Approaches to Asthma. New York, Marcel Dekker, Inc; 2002. pp. 167-210.
Zimmermann N, Rothenberg ME. Role of the Eotaxin Subfamily of Chemokines in Allergic Eosinophilic Inflammation. In: Eissa NT, Huston DP, Lenfant C, eds. Lung Biology in Health and Disease: Therapeutic Targets of Airway Inflammation. New York: Marcel Dekker, Inc., 2003 pp 421-463.
Guajardo JR, Rothenberg ME. Eosinophil-Associated Gastrointestinal Disorders: Clinical Features and Pathogenesis. In: Metcalfe D, Sampson H, Simon RA (eds). Food Allergy: Adverse Reactions to Foods and Food Additives, (3rd Edition) Malden, Massachusetts: Blackwell Publishing, Inc., 2003, pp 217-226.
Rothenberg ME. Inflammatory Effector Cells / Cell Migration. In: Leung DYM, Geha R, Sampson H, Szefler A (eds): Pediatric Allergy: Principles and Practice St. Louis: Mosby, 2003, pp 51-68.
Rothenberg ME, Hogan SP. The eosinophil. Annu Rev Immunology, 2006; 24:147-74.
Fulkerson PC, Rothenberg ME. Chemokines CXC: CXCL9 (mig). In: Laurent GJ, Shapiro SD (eds): Encyclopedia of Respiratory Medicine, London: Elsevier Science, 2006, pp 398-401.
Rothenberg ME. Eosinophilic Syndromes. In: Goldman L, Ausiello D (eds): Cecil Textbook of Medicine, (23rd Edition) Philadelphia: WB Saunders, in press.
Rothenberg ME, Furuta GT. Eosinophilic Esophagitis. In: Yamada T (ed), Alpers DH, Kalloo A, Kaplowitz N. Owyang C, Powell D (associate editors): Textbook of Gastroenterology (5th Edition), in press.
Zuo Li, Rothenberg ME. Eosinophil Associated Gastrointestinal Disorders (EGID). In: Rich RR, Shearer WT, Fleisher TA, Schroeder H, Weyand C, Frew AJ (eds): Clinical Immunology (3rd Edition), Edinburgh, UK: Martin Mellor Publishing Services, Ltd, in press.
Rothenberg ME. Eosinophilic Gastroenteropathies. In: Adkinson NF, Busse WW, Bochner BS, Holgate ST, Simons FER, Lemanske RF (eds): Middleton's Allergy (7th Edition), London: Elsevier, in press.
Rothenberg ME. Biology of Eosinophils. In: Adkinson NF, Busse WW, Bochner BS, Holgate ST, Simons FER, Lemanske RF (eds): Middleton's Allergy (7th Edition), London: Elsevier, in press.
Rothenberg ME. Eosinophils. In: Mestecky J, Bienenstock J, Lamm ME, Mayer L, McGhee JR, Strober W (eds): Mucosal Immunology, London: Elsevier Science, 2005, pp 717-735 (Vol. 1).
Rothenberg ME, Hogan SP: The eosinophil, Annu Rev Immunology, 2006; 24:147-74.
Fulkerson PC, Rothenberg ME. Chemokines CXC: CXCL9 (mig). In: Laurent GJ, Shapiro SD (eds): Encyclopedia of Respiratory Medicine, London: Elsevier Science, 2006, pp 398-401.
Rothenberg ME. Eosinophilic Syndromes. In: Goldman L, Ausiello D (eds): Cecil Medicine: Expert Consult: Online and Print (Cecil Textbook of Medicine), (23rd Edition) Philadelphia: WB Saunders, 2007.
Zuo Li, Rothenberg ME. Eosinophil Associated Gastrointestinal Disorders (EGID). In: Rich RR, Shearer WT, Fleisher TA, Schroeder H, Weyand C, Frew AJ (eds): Clinical Immunology (3rd Edition), Edinburgh, UK: Martin Mellor Publishing Services, Ltd 2008.
Rothenberg ME, Furuta GT. Eosinophilic Esophagitis. In: Yamada T (ed), Alpers DH, Kalloo A, Kaplowitz N. Owyang C, Powell D (associate editors): Textbook of Gastroenterology (5th Edition), in press.
Rothenberg ME. Eosinophilic Gastroenteropathies. In: Adkinson NF, Busse WW, Bochner BS, Holgate ST, Simons FER, Lemanske RF (eds): Middleton’s Allergy (7th Edition), London: Elsevier, in press.
Rothenberg ME. Biology of Eosinophils. In: Adkinson NF, Busse WW, Bochner BS, Holgate ST, Simons FER, Lemanske RF (eds): Middleton’s Allergy (7th Edition), London: Elsevier, in press.
Special Interests
Eosinophilia; eosinophilic disorders; asthma; allergy; food allergy
Scientific Reviews
Editorial Boards
Scientific Expert Panel
Scientific and Medical Boards
- 2000-2003 Gift of Life Foundation (a bone marrow donor registry)
- 2001- American Partnership for Eosinophilic Disorders
- 2002- International Advisory Board for "Eosinophil Rising
- 2003 3rd Biennial International Eosinophil Symposium
- 2003- Executive Committee, International Eosinophil Society
- 2006- The International Gastrointestinal Eosinophiilc Researchers (TIGER) Steering Committee
Recent Invited Lectures and Symposia
2001
- VIII Symposium on Immunological, Chemical and Clinical Problems on Food Allergy, Venice, Italy, Invited Speaker
- Meakins-Christie Workshop on Pathogenesis and Treatment of Asthma and COPD: Current and Future Aspects, Montreal, Canada, Invited Speaker
- The Toxicology Forum 2001 Annual Winter Meeting, Washington, DC, Invited Speaker
- ILSI Health and Environmental Sciences Institute, Protein Allergenicity Subcommittee, Washington, DC, Invited Participant
- Immunobiology Seminar Series, Mt. Sinai Medical Center, New York, NY, Invited Speaker
- Immunology Seminar Series, Beirne B. Carter Center for Immunology Research, University of Virginia Health System, Charlottesville, Virginia, Invited Speaker
- American Gastroenterological Association, Digestive Disease Week 2001, Atlanta, Georgia, Invited Speaker
- International Eosinophil Society, Eosinophil 2001 International Symposium, Banff, Alberta, Canada, Invited Speaker
- Schneider's Children's Hospital, Israel, Invited Speaker
- Aspen Allergy Conference, Given Institute of Pathobiology, Aspen, Colorado, Invited Speaker
- John Curtin School of Medical Research, Australian National University, Canberra, Australia, Invited Speaker
2002
- 5th Annual Meakins Christie Workshop on Pathogenesis and Treatment of Asthma, Montreal, Canada, Invited Speaker
- American Academy of Allergy, Asthma and Immunology annual meeting, Postgraduate Plenary Session, Invited Speaker
- 18th Annual Dr. Dorothy Wiselberg Seminar, The Respiratory Division and the Meakins-Christie Laboratories, Montreal, Canada, Invited Speaker
- Southeastern Allergy, Asthma and Immunology Society, 57th Annual Meeting, Sea Island, Georgia, Invited Speaker
- St. Louis University, Cardinal Glennon Children's Hospital, Pediatric Grand Rounds, St. Louis, Missouri, Invited Speaker
- NIH, Laboratory of Allergic Disease, Invited Speaker
- Johns Hopkins Medical Center, Invited Speaker
- Cleveland Clinic, Invited Speaker
2003
- Meakins Christie Workshop on Asthma and COPD, Montreal, Quebec Canada, Invited Speaker
- American Academy of Allergy, Asthma and Immunology annual meeting, Workshop, Denver, Colorado, Invited Speaker
- The Emery Educational Society of Cincinnati Children's Hospital Medical Center, Invited Speaker
- University of Southern California ENT Conference, Invited Speaker
- University of California at Los Angeles, Department of Allergy and Immunology Conference, Invited Speaker
- Federation of Clinical Immunology Societies (FOCIS) annual meeting, Paris, France, Invited Speaker
- University of Alabama Birmingham, Invited Speaker
- McMaster University, Distinguished Speaker Series, Hamilton, Ontario, Canada, Invited Speaker
- Arginine Symposium, Southampton Princess Hotel, Bermuda, Invited Speaker
- Hypereosinophil Syndromes Workshop, Snowmass Village, Colorado, Invited Speaker
- The 3rd International Eosinophil Symposium – Eosinophil Rising, Snowmass, Colorado, Invited Speaker and Moderator
- World Allergy Organization (WAO) Congress – XVIII ICACI, Vancouver, Canada, Invited Plenary Speaker
2004
- Building a Better World Through Medicine II, Jerusalem, Israel
- University of Illinois and Rush University, Division of Allergy and Immunology, Chicago, Illinois, Invited Speaker
- Northwestern University, Division of Allergy, Chicago, Illinois, Invited Speaker
- American Academy of Allergy, Asthma and Immunology annual meeting, Postgraduate Symposium, The Burton Zweiman Lectureship, San Francisco, California, Invited Speaker
- American Academy of Allergy, Asthma and Immunology annual meeting, Workshop, San Francisco, California, Invited Plenary Speaker
- American Gastroenterological Association, Digestive Disease Week 2004, New Orleans, Louisiana, Invited Speaker
- Allergy Fellows Symposium, Orlando, Florida, Invited Speaker
- Israel Allergy Academy, Invited Speaker
- Department of Pediatrics, Asaf Medical Center, Ramla, Israel, Invited Speaker
- Tel Aviv Sourasky Medical Center, Israel, Department of Gastroenterology, Invited Speaker
- Kfar Saba Medical Center, Department of Medicine, Israel, Grand Rounds, Invited Speaker
- XXIII Annual Congress of the European Academy of Allergology and Clinical Immunology, Amsterdam, Invited Speaker
- Department of Medicine, Asaf Medical Center, Ramla, Israel, Invited Speaker
- Department of Gastroenterology, Tel Aviv University, Israel, Invited speaker
- Department of Pediatrics, Pediatric Grand Rounds, Schneider's Children's Hospital Medical Center, Israel, Invited Speaker
2005
- Controversies and New Findings in Allergies CYNA Meeting, Madrid, Spain, Invited Speaker
- Biennial Congress of the International Eosinophil Society, Bern, Switzerland, Invited Speaker
- Federation of Clinical Immunology Societies (FOCIS) annual meeting, Boston, Invited Speaker
- Idea Congress s.r.l Rome, DAM 8 2005, Rome, Italy, Invited Speaker
- Aspen Allergy Conference, Aspen, Colorado, Invited Speaker
- Japanese Society for Immunology (JSI) Presidential Symposium, Yokahama, Japan, Invited Speaker
- American College of Allergy, Asthma and Immunology, Annual Meeting, Invited Plenary Speaker
2006
- American Academy of Allergy, Asthma and Immunology, Annual Meeting, Miami, Florida, Invited Speaker
- Keystone Symposium on Allergy, Allergic Inflammation and Asthma, Breckenridge, Colorado, Invited Speaker
- Digestive Disease Week / Eosinophilic Gastrointestinal Disorders meeting, Los Angeles, California, Invited Speaker
- Division of Allergy and Immunology, University of Michigan, Ann Arbor, Michigan, Invited Speaker
- Eosinophils in GI Health and Disease, Children's Hospital of Philadelphia, Invited Speaker
- American Partnership for Eosinophilic Disorders (APFED) Annual Meeting, Philadelphia, Pennsylvania, Invited Speaker
- Blue Grass Allergy Society, Lexington, Kentucky, Invited Speaker
- Israeli Association of Allergy and Clinical Immunology (Israeli Medical Association), Invited Speaker
- North American Society Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) Postgraduate Course, Orlando, Florida, Invited Speaker
- First International Gastrointestinal Eosinophilic Research Symposium (FIGERS), Orlando, Florida, Invited Speaker
- American College of Allergy, Asthma and Immunology, Annual Scientific Meeting, Philadelphia, Pennsylvania, Invited Speaker
- American Society of Hematology annual meeting, Orlando, Florida, Invited Speaker
2007
- Boston City Wide Allergy and Immunology Rounds, Boston, Massachusetts, Invited Speaker
- 10th Annual Meakins Christie Workshop on Asthma and COPD, Montreal, Quebec Canada, Invited Speaker
- American Academy of Allergy, Asthma and Immunology annual meeting, Workshop, San Diego, California, Invited Speaker
- American Academy of Allergy, Asthma and Immunology annual meeting, Symposium, San Diego, California, Invited Speaker
- Los Angeles Children’s Hospital Pediatric Grand Rounds – 4th Annual Carolyn and Warren Richards Allergy Lecture, Los Angeles, California, Invited Speaker
- International Eosinophil Society Annual Meeting, Salt Lake City, Utah, Invited Speaker
- Distinguished Speaker Seminar Series, National Jewish Hospital, Denver, Colorado, Invited Speaker
- Long Island Asthma and Allergy Society, Montauk, New York, Invited Speaker
2008
- Medical School Rounds, Sackler Medical School, Assaf-Harofeh, Medical Center, Israel
- Charles E. Reed Lecture, Mayo Clinic, Rochester, Minnesota
- American Academy of Allergy, Asthma, and Immunology Annual Meeting, Philadelphia, Pennsylvania, Invited Speaker
- 9th Annual Burton A. Shatz Visiting Professor Lecture, University of Washington University, St. Louis
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical Center: