Richard E. Harris, MD
Title
Director, Bone Marrow Failure Clinic
Appointment
Professor of Clinical Pediatrics, University of Cincinnati College of Medicine
Email
richard.harris@cchmc.org
Phone
513-636-8610
Fax
513-636-7951
Bio
Dr. Harris's primary interest is in aplastic anemia and the various forms of hereditary bone marrow failure syndromes. He is active with the Fanconi Anemia Research Fund presenting at both the annual family meeting and the annual scientific meeting. Likewise he is active in the field of Shwachman Diamond syndrome and is developing a US / Canadian SDS Registry. He also is participating in the development of the International SDS Registry. He is director of the Bone Marrow Failure Clinic at Cincinnati Children's Hospital where several hundred children are followed with these disorders. He is active in developing safe approaches to bone marrow transplantation for children with these disorders. His interest in these areas were recognized by the presentation to him of the Lifetime Achievement Award by the Fanconi Anemia Research Fund in 2005.
Outside of his medical interests, he is a scoutmaster of a very active and large Boy Scout Troop in Cincinnati and has been presented the Silver Beaver Award for his scouting activities, the highest award a volunteer scouter can receive.
Credentials
MD: University of Virginia School of Medicine, Charlottesville, VA, 1973.
Residency: Pediatrics, Vanderbilt University Medical Center, Nashville, Tenn., 1973-1976.
Fellowship: Pediatric Hematology / Oncology, James Whitcomb Riley Hospital for Children, Indianapolis, Ind., 1976-1979.
Certification: Pediatrics, 1978; Pediatric Hematology / Oncology, 1980.
Awards and Honors
- Lifetime Achievement Award, from the Fanconi Anemia Research Fund, 2005
Research
Transplantation for children with bone marrow failure syndromes (Fanconi anemia, Shwachman Diamond syndrome, dyskeratosis congenita, amegakaryocytic thrombocytopenia, Diamond Blackfan anemia) and aplastic anemia. Cytogenetic abnormalities in Fanconi anemia.
Presentations
Invited Speaker, "Fanconi Anemia: A Primer for Cytogeneticists." Ohio Valley Regional Cytogenetics Meeting, Cincinnati Children's Hospital Medical Center, May 2003.
Invited Speaker, "Fanconi Anemia and other Bone Marrow Failure Syndromes." Columbus Children's Hospital, May 2003.
Publications, Most Recent
Connect to Richard Harris' publications on PubMed
Farzin A, Davies S, Smith FO, Filipovich A, Hansen M, Harris RE. Matched sibling door bone marrow transplant for Fanconi anemia patients: an update of the Cincinnati Children's experience. Br J Haematol 136:633-40, 2007 (PMID ____)
Wagner JE, Eapen M, MacMillan M, Harris RE, Pasquini R, Boulad F, Zhang M-J, Auerbach AA. Unrelated donor bone marrow transplantation for the treatment of Fanconi anemia. Preprint Blood October 12, 2006 (PMID: 17038525)
Kelly PF, Radtke S, von Kalle C, Balcik B, Bohn K, Mueller M, Schuesler T, Haren M, Reeves L , Cancelas J, Leemhuis T, Harris R, Auerbach A, Smith FO, Davies SM, Williams DA: Collection and genetic correction of Fanconi anemia hematopoietic stem cells. Molecular Therapy 15:211-9, 2007 (PMID _____)
Mehta PA, Ileri I, Harris RE, Williams DA, Auerbach AD, Smith FO, Mo J, Smolarek T, Kelly P, Davies SM: Chemotherapy for myeloid malignancy in children with Fanconi anemia. Pediatr Blood Cancer, Preprint April 11, 2006 (PMID: 16609946)
Deeg HJ, O'Donnell M, Tolar J, Agarwal R, Harris RE, Feig S, Territo MC, Collins RH, McSweeney PA, Copelan EA, Khan SP, Woolfrey A, Storer B. Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy. Blood 108:1485-91, 2006 (PMID 16684959)
Gaynon PS, Harris RE, Altman AJ, Bostrom BC, Breneman J, Hawks R, Steele D, Zipf T, Trigg M. Bone marrow transplantation versus prolonged, intensive chemotherapy for children with acute lymphoblastic leukemia and an initial bone marrow relapse within twelve months of the completion of primary therapy: Children's Cancer Group CCG-1941. J Clin Oncol 24:3150-6, 2006 (PMID 16717292)
Chan EL, Harris RE, Emery K, Gelfand M, Collins M, Gruppo RA. Favorable histology: MYNC amplified stage 4S neonatal neuroblastoms. Pediatr Blood Cancer 48:479-82, 2007 (PMID 16333837)
Jarrar M, Gaynon PS, Periclou AP, Fu C, Harris RE, Stram D, Altman A, Bostrom B, Breneman J, Steele D, Trigg M, Zipf T, Avramis VI. Asparagine depletion after pegylated E. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: A Children's Cancer Group study (CCG-1941). Pediatr Blood Cancer 47:141-6, 2006 (PMID 16425271)
Oh H, Loberiza FR, Zhang M, Ringden O, Akiyama H, Asai T, Miyawaki S, Okamoto S, Horowitz MM, Antin JH, Bashey A, Bird JM, Carabasi MH, Fay JW, Gale RP, Giller RH, Goldman JM, Hale GA, Harris RE, Henslee-Downey J, Kolb, H-J, Lotzow MR, McCarthy PL, Neudorf, SM, Serna DS, Socie G, Tiberghien P, Barrett AJ: Comparison of Graft-vs-host disease and survival after HLA-identical sibling bone marrow transplantation in different ethnic groups. Blood 105:1408-16, 2005 (PMID 15486071)
Professional Organization Memberships
- American Society of Hematology
- American Society of Clinical Oncology
- Children's Oncology Group
- Americian Society of Pediatric Hematology/Oncology
- American Society of Blood and Marrow Transplantation
- National Marrow Donor Program
- International Bone Marrow Transplant Registry
- Autologous Blood and Marrow Transplant Registry
- International Fanconi Anemia Registry
- Diamond-Blackfan Anemia Registry
- Severe Chronic Neutropenia International Registry
- Storage Disease Collaborative Study Group
Abstracts
Harris RE, Smolarek TA, Monzon S, Smith FA, Davies S, Williams DA: Retrospective Cytogenetic and FISH Analyses in Fanconi Anemia Patients Evaluated at Cincinnati Children's Hospital Medical Center (CCHMC). Fanconi Anemia Scientific Meeting, Geneva, Switzerland, October, 2005 (oral presentation).
Harris RE. Bone Marrow Transplantation for Fanconi Anemia. Fanconi Anemia Family Meeting, Camp Sunshine, Sebago Lake, Casco, ME, August 2005.
Bagby G, Yates, J, McWeeney S, Park B, Rathbun G, Pilonetto D, Harris R, Wagner J, Pals G, Lau, SY, Harrington, C, Mori, M, Pasquini R. Clonal evolution of Fanconi anemia (FA) stem cells results from clonal adaptation and clonal selection. A report from the International Fanconi Anemia Transcriptome Consortium. ASH Abstract # 3416. Blood 104, 932a, 2004.
Gluckman E, Rocha V, Ionescu I, Pasquini R, Harris R, Wagner J, Kurtzberg J, Duval M, Darbyshire PJ, Locatelli MN, Fernandez MN. Results of unrelated cord blood transplants in Fanconi anemia. ASH Abstract # 2145. Blood 104: 590a, 2004.
Harris RE, Morris E, Warkentin P, Vlachos A, Chang M, Cairo MS. Safety and efficacy of CBV followed by autologous PBSC transplant in children with lymphoma after failed induction or first relapse – A Children's Oncology Group Study. ASH Abstract #899. Blood 104: 257a, 2004
Wagner JE, Eapan M, Harris RE, MacMillan ML, Auerbach AD. Unrelated donor transplantation for Fanconi anemia: analysis of prognostic factors impacting engraftment and survival. ASH Abstract # 824. Blood 104: 235a, 2004
Harris RE, Smolarek T, Saal H. Retrospective cytogenetic analysis in FA patients evaluated at Cincinnati Children's Hospital Medical Center, FA Scientific Meeting, Cambridge, MA, October 14-17, 2004, poster presentation
Harris RE. Matched Sibling Donor Bone Marrow Transplantation in Fanconi Anemia: An Update of the Cincinnati Children's Experience. FA Scientific Meeting, Cambridge MA, October 14-17, 2004, oral presentation.
Harris RE. Matched Sibling Donor Bone Marrow Transplantation in Fanconi Anemia: An Update of the Cincinnati Children's Experience. FA Family Meeting, August 14, 2004, Maine, oral presentation.
Tinkle BT, Harris RE, Franz DN, Bailey L, Grabowski GA. Long-Term Outcome of Stem Cell Transplant in a Patient with Hunter Syndrome. Am Soc Human Genetics, October 2004.
Farzin A, Harris RE. Matched sibling donor bone marrow transplantation in Fanconi anemia: an update of the Cincinnati Children's experience. Pediatric Academic Societies' Annual Meeting, 2004. In Pediatr Blood Cancer 42:517, 2004 (Platform Presentation, abstract #1676).
Blackman S, Davies S, Harris R: Failure of metoclopramide as adjunct therapy in pediatric Diamond-Blackfan anemia patients. Pediatric Academic Society Annual Meeting, 2004. in Pediatr Blood Cancer 42: 509, 2004 (Poster Presentation, Abstract # 1646).
Blackman SC, Davies SM, Smith FA, Harris RE. Failure of metoclopramide as adjunct therapy in pediatric Diamond-Blackfan anemia patients. Platform presentation at the Fifth Annual Diamond Blackfan Anemia International consensus Conference, April 2003.
Special Interests
Bone marrow failure syndromes such as Fanconi anemia, Shwachman Diamond Syndrome, Dyskeratosis Congenita, Congenital Amegakaryocytic Thrombocytopenia, Diamond Blackfan Anemia, and severe aplastic anemia.
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical Center:
