Neuroblastoma

Opportunities for Research Participation

Physicians and researchers from the Neuroblastoma Advanced Therapies Center at Cincinnati Children's Hospital Medical Center offer clinical research studies for patients with neuroblastoma.

• 131-I-MIBG: Expanded Access:  An Open Label, Expanded Access Protocol Using I-Metaiodobenzylguanidine (131I-MIBG) Therapy in Patients With Refractory Neuroblastoma
• ADVL0413: Phase I Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib in Children with Refractory Solid Tumors or Refractory Leukemias
• ADVL0525: A Phase II Study of Pemetrexed Disodium in Young Patients With Relapsed or Refractory Solid Tumors
• ADVL0612: A Phase I Study of Sunitinib (SU11248), an Oral Multi-Targeted Tyrosine Kinase Inhibitor, in Children with Refractory Solid Tumors
• ADVL0714: A Phase I Study of VEGF Trap in Children with Refractory Solid Tumors
• ADVL0812: A Phase I Study of MLN8237, an Oral Selective Small Molecule Inhibitor of Aurora A Kinase, in Pediatric Patients With Relapsed/Refractory Solid Tumors and Leukemia
• ANBL0621: A Phase II Trial of ABT-751 in Children with Relapsed or Refractory Neuroblastoma
• NANT 2001-02: 131I-Metaiodobenzylguanidine (MIBG) with Intensive Chemotherapy and Autologous Stem Cell Rescue for High-Risk Neuroblastoma
• NANT 2004-04: Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb™ (LXS) Oral Powder In Patients with Recurrent or Resistant Neuroblastoma
• NANT 99-02: Modulation of Intensive Melphalan (L-PAM) by Buthionine Sulfoximine (BSO) with Autologous Stem Cell Support for Recurrent High-Risk Neuroblastoma (A Phase I Study)
• NCI-07-C-0040: A Phase I Trial of the Monoclonal Antibody HGS-ETR2 (Lexatumumab) in Patients with Refractory Pediatric Solid Tumors
• VITAC: A Pilot Study of the Addition of Bevacizumab to Vincristine, Oral Irinotecan and Temozolomide (VOIT regiment) for Relapsed/Refractory Pediatric Solid Tumors

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