Overview
Find detailed information on selected clinical trials for Brain Tumors at Cincinnati Children's Hospital Medical Center.
There are two versions of some of the trials. While they contain the same basic information, one version is geared towrad healthcare professionals and the other is geared toward families.
| Trial | Healthcare Professional Version | Family-Friendly Version |
| ACNS0122: A Phase II Study to Assess the Ability of Neoadjuvant Chemotherapy +/- Second Look Surgery to Eliminate All Measurable Disease Prior to Radiotherapy for Non-Germinomatous Germ Cell Tumor (NGGCT) |
Professional |
Family-Friendly |
| ADVL0414: A Phase Study of Temozolomide, Oral Irinotecan, and Vincristine for Children with Refractory Solid Tumors |
Professional |
Family-Friendly |
| A Pilot Study of Temozolomide and 06Benzylguanine For Treatment of Newly Diagnosed High Grade Glioma, Using Autologous Peripheral Blood Stem Cells Genetically Modified for Chemoprotection |
Professional |
Family-Friendly |
| ADVL0416: A Phase 1 Study of SAHA In Pediatric Patients with Recurrent or Refractory Solid Tumors (Including Lymphomas) and Leukemia Followed by a Phase I Study of SAHA in Combination with 13 Cis-Retinoic Acid for Patients with Selected Recurrent/Refractory Solid Tumors |
Professional |
Family-Friendly |
| ACNS0224: A Phase I/II Study of Topotecan With G-CSF and Radiation Therapy in Children with Malignant Intrinsic Pontine Brainstem Gliomas of Childhood |
Professional |
Family-Friendly |
| ACNS0121: A Phase II Trial of Conformal Radiation Therapy For Pediatric Patients With Localized Ependymoma, Chemotherapy Prior to Second Surgery for Incompletely Resected Ependymoma and Observations for Completely Resected, Differentiated, Supratentorial Ependymoma |
Professional |
Family-Friendly |
| ADVL0515: A Phase I Study of Vinblastine in Combination with Carboplatin for Children with Newly Diagnosed and Recurrent Low-Grade Gliomas |
Professional |
Family-Friendly |
| ACNS0223: a pilot study using carboplatin, vincristine and temozolomide for children < 10 years with progressive OR symptomatic low-grade gliomas |
Professional |
Family-Friendly |
| ACNS0222: A Phase II Study of Motexafin-Gadolinium and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood |
Professional |
Not Available |
| ADVL0525: A Phase II Study of Pemetrexed Disodium in Young Patients With Relapsed or Refractory Solid Tumors |
Professional |
Not Available |