Diabetes Center

Lawrence M. Dolan, MD

Appointment

Professor of Pediatrics

Phone

513-636-4744

Bio

Lawrence M. Dolan, MD, is board-certified in Pediatrics and Pediatric Endocrinology. He has been on the faculty of Cincinnati Children's Hospital Medical Center in the Department of Pediatrics for the University of Cincinnati College of Medicine since 1983.

Dr. Dolan is a Professor of Pediatrics in the Division of Endocrinology. His research focuses on the epidemiology and genetics of obesity, insulin resistance, abnormal carbohydrate metabolism, diabetes and their relationships to the development and progression of cardiovascular disease.

Dr. Dolan received his bachelor of science degree from the University of San Francisco. He received his doctor of medicine degree from the University of California at Los Angeles.

Dr. Dolan completed his pediatric internship and residency at the University of Minnesota. He also served as chief resident. He obtained fellowship training in Pediatric Endocrinology at the University of Virginia.

Credentials

BS: University of San Francisco, San Francisco, CA, 1971.

MD: University of California at Los Angeles, Los Angeles, CA, 1976.

Residency: Pediatrics, University of Minnesota, Minneapolis, MN, 1976 to 1979. Chief Resident, 1979.

Fellowship: University of Virginia, Charlottesville, VA

Certification: Pediatrics, 1982; Pediatric Endocrinology, 1983.

Awards and Honors

Awarded "Best Doctors in America" 2004-2008
University of Michigan School of Medicine, Visiting Professor, November 27-28, 2006.
Cardiometabolic Congress. “Hyperlipidemia in Children with type1 and type 2 diabetes: A rapidly evolving issue”. Boston, MA, September 28, 2007.
Endocrine Society national Meeting, Invited speaker, “Optimal treatment of dyslipidemia in childhoohd and adolescents, San Francisco, CA, June 17, 2008
Faculty Teaching Award, Cincinnati Children's Hospital Medical Center, 1987, 1988
Diabetes Clinician of the Year, American Diabetes Association, Ohio Affiliate, 1994

Research

Epidemiology and genetics of obesity, insulin resistance, abnormal carbohydrate metabolism, diabetes and their relationships to the development and progression of cardiovascular disease

Research Grants and Contracts

Understanding Social Status Input on Adolescent Health (RO1HD41527)
Elizabeth Goodman - Principal Investigator 12/01/07-11/30/11
NIH/NICHD

Spatial Epidemiology in diabetes in the SEARCH for diabetes in youth study (RO1DK077131)
Angela Liese - Prinicpal investigator
NIH/NIDDK

Mechanisms of vascular dysfunction in obesity and the metabolic syndrome (K23HL080447)
Elaine Urbina - Principal Invesitigator 6/01/06-5/31/11
NIH/NHLIB

Adolescent Bariatrics: Assessing Benefits and Risks (U01 DK072493)
Thomas Inge - Principal Investigator 7/01/06-3/31/11
National Institutes of Health

SEARCH for Diabetes in Youth 2: Ohio Center (1 U01 DP000248-01)
LM Dolan - Principal Investigator 10/01/05- 9/30/10
Center for Disease Control and the National Institutes of Health

CV Disease in Adolescents with type 2 diabetes (RO1HL076269-01)
Stephen R. Daniels, Principal Investigator 3/01/05-2/30/09
Lawrence Dolan, co-investigator
NIH/NHLIB

Publications, Most Recent

Patton SR, Dolan LM, Powers SW. Differences in family mealtime interactions between young children with type 1 diabetes and controls: implications for behavioral intervention. Journal of Pediatric Psychology (in press) 2008.

Inge T, Go M, Bean J, Courcoulas A, Harmon C, Wilson K, Daniels S, Garcia V, Brandt M, Dolan LM. Reversal of type 2 diabetes and improvements in cardiovascular risk factors following surgical weight loss in adolescents. Pediatrics (in press), 2008.

Maahs DM, Snively BM, Beyer J, Imperatore G, Bell R, Mayer-Davis EJ, Dolan LM, Pettitt DJ, Hirsch I, Rodriguez B, Dabelea D. Birth Weight and Elevated Albumin to Creatinine Ratio in Youth with Diabetes: The SEARCH for Diabetes in Youth Study. Pediatric Nephrology, (in press) 2008.

Albers JJ, Marcovina SM, Imperatore G, Snively BM, Stafford J, Jujimotto WY, Mayer-Davis EJ, Petitti DB, Pihoker C, Dolan L, Dabalea DM. Prevalence and determinants of elevated apolipoprotein B and dense LDLD in youths with type 1 and type 2 diabetes.J Clin Endocrinol Metab Dec 18, 2007 (Epub)

Rewers A, Klingensmith G, Davis C, Petitti DB, Pihoker C, Rodriguez B, Schwartz ID, Imperatore G, Williams D, Dolan LM, Dabelea D. The Presence of Diabetic Ketoacidosis at Diagnosis of Diabetes Mellitus in Youth: The SEARCH for Diabetes in Youth Study.Pediatrics (in press) 2008.

Piazza- Waggoner C, Modi AC, Powers SW, Williams LB, Dolan LM, Patton SR. Observational assessment of family functioning in families with children who have type 1 diabetes.J Dev Behav Pediatr (in press) 2008.

Woo JG, Dolan LM, Morrow AL, Geraghty SR, Goodman E. Breastfeeding helps explain racial and socioeconomic status disparities in adolescent adiposity. Pediatrics (in press) 2008.

Maahs DM, Snively BM, Bell R, Dolan LM, Hirsch I, Imperatore G, Linder B, Marcovina S, Mayer-Davis EJ, Pettitt DJ,Rodriguez B, Dabelea D. Higher Prevalence of Elevated Albumin Excretion in Youth with Type 2 than Type 1 Diabetes: The SEARCH for Diabetes in Youth Study.Diabetes Care 2007;30:2593-2598.

Kalra M, Pal P, Kaushal R, Amin RS, Dolan LM, Fitz K, Kumar S, Sheng X, Guha S, Mallik J Deka R, Chakraborty R. Association of ApoE Genetic Variants with Obstructive Sleep Apnea in Children.Sleep Medicine July 18, 2007 (Epub).

Elder DA, Wooldridge JL, Dolan LM, D'Alessio DA. Glucose Tolerance, Insulin Secretion, and Insulin Sensitivity in Children and Adolescents with Cystic Fibrosis and No Prior History of Diabetes.J Pediatrics 2007;151:635-8.

Crimmins NA, Dolan LM, Martin LJ, Bean JA, Daniels SR, Lawson ML, Goodman E, Woo JG. Stability of Adolescetn Body Mass Index During 3 Years of Follow-up.J Pediatrics 2007;151:383-7.

Patton SR, Dolan LM, Henry R, Powers SW. Parental fear of hypoglycemia: Young children treated with continuous subcutaneous insulin infusion.Pediatric Diabetes 2007;8:362-8.

Urbina EM, Bean JA, Daniels SR, D'Alessio D, Dolan LM. Overweight and Hyperinsulinemia Provide Individual Contributions to Compromises in Brachial Artery Distensibility in Healthy Adolescents and Young Adults. J American Society of Hypertension (in press) 2007.

Goodman E, Daniels SR, Meigs J, Dolan LM. Instability of the diagnosis of metabolic syndrome in healthy adolescents.Circulation 2007;115:2316-22.

Crimmins NA, Woo JG, Kaushal RD, Deka R, Dolan LM, Martin LJ. Adiponectin Receptor 1 Gene (ADIPOR1) Variation is Associated with Decreased HOMA-IR Conditional on Adiposity in African-Americans.Obesity Research 2007;15:1903-7.

Goodman E, Daniels SR, Dolan LM. Socioeconomic disparities in insulin resistance: results form the Princeton School District Study.Psychosomatic Medicine 2007;69:61-67.

Petitti D,B, Imperatore P, Palle SL, Daniels SR, Dolan LM, Kershnar AK, Marcovina S, Pettitt DJ, Pihoker C for the SEARCH Study Group. Serum lipids and glucose control: the SEARCH for Diabetes in Youth Study.Archives of Pediatric and Adolescent Medicine 2007;116:159-65.

Patton SR, Dolan LM, Powers S. Dietary Adherence and Associated Glycemic Control in Families of Young Children with Type 1 Diabetes.J American Dietetic Association 2007;107:46-52.

Martin LJ, Woo JG, Geraghty SR, Altaye M, Davidson BS, Banach W, Dolan LM, Ruiz-Palacios GM, Marrow AL. Adiponectin is present in human breast milk and is associated with maternal factors.Am J Clin Nutr 2006; 83:1106-11.

Kershnar AK, Daniels SR, Imperatore G, Palla SL, Petitti DB, Pettitt DJ, Marcovina AM, Dolan LM, Hamman RF, Liese AD, Pihoker C, Rodriguez, for the SEARCH Study Group. Prevalence of lipid abnormalities in youth with type 1 and type 2 diabetes.J Pediatr 2006;149:314-319.

Patton SR, Dolan LM, Powers S. Dietary Adherence and Associated Glycemic Control in Families of Young Children with Type 1 Diabetes.J Am Diet Assoc 2007;107(1):46-52.

Patton SR, Dolan LM, Powers SW. Mealtime interactions relate to dietary adherence and glycemic control in young children with type 1 diabetes.Diabetes Care 2006;29:1002-6.

Dabelea D, D'Agostion RB, Mayer-Daivs EJ, Pettitt DJ, Imperatore GA, Dolan LM, Pihoker C, Hillier TA, Marcovina SM, Linder B, Ruggiero AM, Hamman RF for the SEARCH for Diabetes in youth Study Group. Testing the Accelerator Hypothesis: Body Size, Beta-Cell Function, and Age at Onset of Type 1(Autoimmune) Diabetes.Diabetes Care 2006;29:290-4.

Woo JG, Dolan LM, Deka R, Kaushal RD, Shen Y, Pal P, Daniels SR, Martin LJ. Interactions between non-contiguous haplotypes in ACDC are associated with plasma adiponectin.Diabetes 2006;55:523-9.

Elder DA, Prigeon RL, Wadwa RP, Dolan LM, D'Alessio DA. β-cell Function, Insulin Sensitivity and Glucose Tolerance in Obese Diabetic and Non-diabetic Adolescents and Young Adults.J Clin Endocrinol Metabol 2006;91:185-191.

Patton SR, Dolan LM, Powers SW. Parent report of mealtime behaviors in young children with type 1 diabetes: implications for better assessment of dietary adherence problems in the clinic.J Dev Behav Pediatr 2006;27(3):202-8.

Woo JG, Dolan LM, Daniels SR, Goodman E, Martin LJ. Adolescent Sex Differences in Adiponectin are Conditional on Pubertal Development and Adiposity.Obesity Research 2005;13:2095-101.

Goodman E, McEwen BS, Dolan LM, Schafer-Kalhoff, Adler NE. Social disadvantage and adolescent stress.J Adolesc Health 2005;37:484-92.

Martin LJ, Woo JG, Daniels SR, Goodman E, Dolan LM. The relationship of adiponectin with insulin and lipids are strengthened with increasing adiposity.J Clin Endocrinol Metab 90:5255-4259, 2005.

Goodman E, Dolan LM, Morrison J, Daniels SR. Factor analysis of clustered cardiovascular risks in adolescence: obesity is the predominant correlate of risk among youth.Circulation 2005;19:1970-7.

Dolan LM, Bean J, D'Alessio D, Cohen RM, Morrison JA, Goodman E, Daniels SR. The frequency of abnormal carbohydrate metabolism and diabetes in a population based screening of adolescents. J Pediatrics 2005;146:751-8.

Goodman E, McEwen BS, Huang B, Dolan LM, and Adler NE. Social Inequalities in Biomarkers of Cardiovascular Risk in Adolescence. Psychosomatic Medicine 2005;67:9-15.

Books and Invited Publications

Crimmins NA and Dolan LM. "Definition, Diagnosis and Classification of Diabetes in Youth" in The Epidemiology of Diabetes in Youth, Dabelea D and Klingensmith G (eds), Informa Healthcare, New York, NY, (in press) 2008.

Dolan LM. "Type 2 diabetes in children and adolescents" in Pediatric Diabetes Sperling MA and Menon RK editors, Kluwer Academic Publishers, 2003.

Dolan LM, Daniels SR. Pieces of the puzzle: diabetes and the structure and function of the heart and blood vessels. J Pediatr 2000; 137:445-6.

Professional Organization Memberships

1986-present Lawson Wilkins Pediatric Endocrine Society
1986-99, 2005-present American Society of Hypertension
1987-present Endocrine Society
1989-present Society for Pediatric Research
1990-present American Diabetes Association
2003-present American Heart Association

Special Interests

Epidemiology of obesity
Insulin resistance
Abnormal carbohydrate metabolism
Diabetes and their relationships to the development and progression of cardiovascular disease

Presentations

Dolan LM. Intensified insulin therapy: risk of hypoglycemia. St Elizabeth Medical Center, Covington, Ky, Jan. 22, 1997.

Dolan LM. Diabetes Prevention Trial. Bethesda Family Practice Center, Norwood, OH, Mar. 18, 1997.

Dey S, Dolan LM, Khoury PR, Klein DJ. Urinary proteoglycan excretion is decreased in insulin dependent diabetes mellitus without overt nephropathy. The Endocrine Society, Minneapolis, MN, June 1997.

Dolan LM, Standifiord DA, Khoury PR, Daniels SR. Greater acceleration in albumin excretion in pediatric subjects with IDDM in the normoalbuminuric range. Diabetes, 46:310A, 1997.

Young LA, Kimball TR, Daniels SR, Standiford DA, Khoury PR, Dolan LM. Lack of decline in nocturnal blood pressure in young patients with IDDM: the effect on diastolic cardiac function and albumin excretion rate. American Diabetes Association, Boston, MA, June 1997, Diabetes 46:0413A, 1997.

Dolan LM, Standiford DA, Khoury PR, Daniels SA. Determinants of albumin excretion in pediatric subjects with insulin dependent diabetes mellitus prior to the onset of microalbuminuria. Diabetes 47:1436A, 1998.

Dolan LM. Investigator's view of the Institutional Review Board. Children's Hospital Medical Center Seminar Series titled Critical Aspects of A Grant Proposal. Cincinnati, OH, Apr. 6, 1998.

Dolan LM. Type 2 Diabetes in Adolescents: the Cincinnati Experience. New Jersey Pediatric Endocrine Society, New Brunswick, NJ, May 21, 1998.

Dolan LM. Diabetes: Differential Diagnosis. St Elizabeth Medical Center, Edgewood, KY, Aug. 21, 1998.

Dolan LM. Prevalence and Incidence of Type 2 Diabetes in Adolescents. Center for Disease Control National Task Force on Type 2 Diabetes in Adolescents. Atlanta, GA, Oct. 5 to 6, 1998.

Dolan LM. Continuous insulin infusion therapy in pediatric subjects: a historical perspective and future challenges. Indianapolis, IN, Oct. 17, 1998.

Dolan LM, Dolan BJ. Optometric patient at risk to develop diabetes, new treatments in diabetes, and the prevention of diabetes. American Optometric Association National Meeting, San Francisco, CA, Dec. 11, 1998.

Dolan LM and the National Diabetes Prevention Trial. An update on the progress of Diabetes Prevention Trial 1. American Optometric Association National Meeting, San Francisco, CA, Dec. 13, 1998.

Dolan LM. Clinical phenotype of adolescents with type 2 diabetes. Center for Disease Control National Task Force on Type 2 Diabetes in Adolescents, Atlanta, GA, Jan. 11 to 12, 1999.

Powers SW, Byars KC, Piazza C, Schwarber L, Standiford D, Dolan LM. Eating behaviors in young children with type 1a diabetes: A comparison to children with cystic fibrosis and non-chronically ill children. American Diabetes Association, San Diego, CA, June 19 to 22, 1999. Diabetes 48:1421A, 1999.

Young LA, Standiford DA, Daniels SR, Dolan LM. Stage of puberty at diagnosis in type 2 diabetes: racial difference in females. American Diabetes Association, San Diego, CA, June 19 to 22, 1999. Diabetes 48:0375A, 1999.

Dolan LM. Epidemiology of type 2 diabetes in African-American
adolescents. National Institutes of Health national task force on type 2 diabetes in adolescents. Chair, subcommittee on African-American adolescents with type 2 diabetes. National Institutes of Health, Washington, DC, July 20 to 21, 1999.

Dolan LM. Diabetic ketoacidosis: pitfalls during treatment. St Elizabeth Medical Center, Edgewood, KY, Sept. 2, 1999.

Dolan LM. Symposium on Type 2 Diabetes of Youth: an Emerging Epidemic. Clinical characteristics of children and adolescents with type 2. Canadian Diabetes Association, Ottawa, Canada, Oct. 15, 1999.

Dolan LM. Medivison symposium Diabetes: Meeting the Challenge. The differentiation of type 1, type 2, and secondary diabetes and MODY in adults and children. League City, TX, Oct. 21, 1999.

Dolan LM. Caring for your Child with Diabetes. Children's Hospital Medical Center Diabetes Center Symposium. Important Diabetes Research Studies: Lessons form the Diabetes Control and complications Trial and the National Diabetes Prevention Trial, Covington, KY, Nov. 5, 1999.