Eosinophilic Disorders
Conditions We Treat

Care for the Full Range of Eosinophilic Disorders

Patients who require information, evaluation and comprehensive treatment for eosinophilic gastrointestinal disorders (EGIDs) can find help at the Cincinnati Center for Eosinophilic Disorders. EGIDs include:
In eosinophilic colitis (EoC), a type of white blood cell called the eosinophil gathers in large numbers in the colon. Too many eosinophils can cause injury and irritation to the colon.
Read more about eosinophilic colitis
Eosinophilic enteritis (EoN) is a rare disease in which a type of white blood cell, the eosinophil, gathers in the small bowel. This causes injury and inflammation in that area.
Read more about eosinophilic enteritis
With eosinophilic esophagitis (EoE), there are a large number of white blood cells called eosinophils in the esophagus. These cells can cause injury and irritation to the esophagus.
Read more about eosinophilic esophagitis (EoE)
In Eosinophilic Gastritis (EoG), a type of white blood cell, called the eosinophil, gathers in large numbers in the stomach. Having too many eosinophils can cause injury and irritation to the stomach. 
Learn about eosinophilic gastritis (EoG)
Hypereosinophilic syndrome (HES) is a rare condition characterized by an overabundance of eosinophils, a type of white blood cell that plays a crucial role in the immune system. This syndrome can lead to various complications as eosinophils can damage tissues and organs when present in excessive amounts.

About Eosinophils

The eosinophil is a specialized cell of the immune system. Learn about what happens when you have high levels of them (eosinophilia), which cause chronic inflammation (eosinophilic disorders).
The eosinophil is a specialized cell of the immune system. This proinflammatory white blood cell generally has a nucleus with two lobes (bilobed) and cytoplasm filled with approximately 200 large granules containing enzymes and proteins with different (known and unknown) functions.
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Eosinophilia is having high levels of eosinophils, which are a type of immune cell that is normally present in the blood and certain tissues. When the body wants to attack a substance, such as an allergy-triggering food or airborne allergen or a parasite, eosinophils respond by moving into the area and releasing a variety of toxins.
Read more about eosinophilia
When the body produces too many eosinophils, they can cause chronic inflammation resulting in tissue damage. Eosinophilic disorders are diagnosed according to the location where the levels of eosinophils are elevated.
Read more about eosinophilic disorders

What Are EGIDs? Watch and Learn