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Clinical Studies Involving Eosinophilic Disorders

The Division of Allergy and Immunology at Cincinnati Children's Hospital Medical Center is actively conducting research to help understand and improve the lives of patients with eosinophilic disorders. Contact us if you are interested in participating in the following clinical studies:

Past Eosinophilic Disorders Research Findings

The Cincinnati Center for Eosinophilic Disorders conducts ongoing research into these rare disorders. Read about some of our past findings:

Date
 Topic
2009
February
 A Pathway for Connecting Intestinal Inflammation with Metobolic Problems is Identified
2008
December
 An Allergy Associated Mediator is Shown to Induce Intestinal Inflammation 
September
 The Mechanism of Mast Cell Growth and Involvement in Hypereosinophilic Syndrome is Defined. 
August
 A New Approach to Blocking Eosinophils in Vivo is Shown in a Pre-Clinical Study. 
July
A New Pathway Involved in Eosinophilic Esophagitis is Identified. 
July
 A Novel Regulatory Molecule PIR-B in Eosinophil Activation and Inhibition is Reported.
June
The Familial Form of Eosinophilic Esophagitis is Described and the Clinical and Genetic Aspects Defined. 
June
The Action of Anti-IL-5 in Eosinophilic Patients is Defined. 
May
The Receptor Involved in Eliciting Allergic Lung Responses to IL-4 and IL-13 is Elucidated. 
March
 Anti-IL-5 Therapy in Patients with Hypereosinophilia is Shown to be Successful. 
January
 The Mechanism of Esophageal Scarring in Eosinophilic Esophagitis is Identified. 
2007
December
 The Key Role of IL-13 in Eosinophilic Esophagitis is Identified. 
March
 A Long Term Follow Up of Eosinophilic Esophagitis Patients is Reported. 
2006
November
 Early Biomarkers for Eosinophilic Esophagitis are Identified.
October The Key Importance of the Eotaxin Receptor CCR3 is Reported. 
August The First Placebo Controlled Trial in Eosinophilic Esophagitis Reports Benefit of Swallowed Fluticasone. 
May
 An In-Vivo Model of Hypereosinophilic Syndrome Involving FIP1L1-PDGFR is Reported. 
February Gene Discovery Linked to Mysterious Chronic Food Allergy: Study offers first molecular insight into eosinophilic esophagitis.
2004
September Two Studies in Science Point to New Evidence in Asthma Development: Eosinophils Have a Key Role in Asthma.
August
Study In The New England Journal of Medicine Indentifies Rapidly Rising Disorder.
January
Study Identifies Breakthrough Treatment For Devastating Blood Disorders.
2001
March Study Identifies Culprits in Food Allergy Inflammation.
2000
December 
Cincinnati Children's Researcher Uncovers Allergy / Reflux Link: Study Has Significant Treatment Implications.
June 
Cincinnati Children's Researchers Uncover Critical Food Allergy Pathway.