Evaluation of Eosinophil-Associated Gastrointestinal Disorders
The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting a clinical and immunological evaluation of eosinophil-associated gastrointestinal disorders. The purpose of this study is to conduct a translational study in patients with primary eosinophil-associated gastrointestinal disorders [EGID] with the aim of developing a databank containing pertinent patient demographic information, tissue samples and DNA. Eosinophil-associated gastrointestinal disorders [EGID] include:
- Eosinophilic esophagitis
- Eosinophilic gastritis
- Eosinophilic enteritis [EE]
- Eosinophilic colitis
- Eosinophilic gastroenteritis [EGE]
This information will facilitate research on the pathophysiology of inflammatory disorders and the development of a verified successful clinical treatment program.
Eligibility
Inclusion Criteria:
Entry criteria prior to endoscopy:
- > 3 years of age
- Clinical symptoms consistent with EGID (e.g., refractory abdominal pain, vomiting, dysphagia)
- Patients with presumed gastrointestinal reflux disease (GERD) that is refractory to therapy
Entry criteria after endoscopy:
- Abnormal levels of eosinophils in the gastrointestinal track OR IS A HEALTHY VOLUNTARY
If you are a patient who may be interested in enrolling in this research study or you have further questions, please contact us at 513-636-5540.
Marc E. Rothenberg, MD, PhD
Bridget Buckmeier
bridget.buckmeier@cchmc.org
513-636-5540
