Eosinophils and Inflammation, an Expanded Study
The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting an expanded study on eosinophils and inflammation. The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum of disease severity of eosinophilic inflammation in humans.
Eligibility
Inclusion Criteria:
- 1- 65 years of age
- Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy
- Other inclusion criteria may include: undergoing endoscopy based on evaluation by a pediatric gastroenterologist at Cincinnati Children's
Exclusion Criteria:
- Recent viral infection (in preceding 1-2 weeks) such as upper respiratory tract infection, tonsillitis, or gastroenteritis. Viral infections in general may suppress or alter some cellular responses, especially lymphocyte responses in vivo
- Oral or esophageal infections including candidiasis in the preceding 2 weeks
- Known diagnosis of another systemic or gastrointestinal inflammatory condition including, but not limited to, ulcerative colitis, Crohn's disease, indeterminate colitis, celiac disease, cystic fibrosis, or immunodeficiency
- Concurrent use of systemic steroids, antihistamines, or other immunomodulatory drugs that may alter cellular responses
- Concurrent use of anticoagulant medications which may alter cellular responses
If you are a patient who may be interested in enrolling in this research study or you have further questions, please contact us at 513-636-5540.
Marc E. Rothenberg, MD, PhD
Bridget Buckmeier
bridget.buckmeier@cchmc.org
513-636-5540
