General and Community Pediatrics

Adam Spanier, MD, MPH

Appointment

Research Instructor

Email

adam.spanier@cchmc.org

Phone

513-636-3170

Fax

513-636-4402

Bio

Adam Spanier, MD, MPH, attended Louisiana State University (LSU) in Baton Rouge where he earned his Bachelors degree. He then continued his education at LSU Health Sciences Center in New Orleans where he earned an MD and MPH. He completed residency training in Pediatrics at Rainbow Babies and Children's Hospital in Cleveland, OH. He is completed a combined General Pediatric Research Fellowship and Pediatric Environmental Health Fellowship in the division of General and Community Pediatrics at Cincinnati Children's. He is currently a faculty member in the division of General and Community Pediatrics, where he is caring for patient in the Lead Clinic and on the Generalist Inpatient Service and is pursuing research. His research goals are to understand how environmental and genetic risk factors interplay in asthma severity and to integrate this knowledge into the improved care for pediatric asthma and prevention of pediatric asthma.

Credentials

MD: Louisiana State University Health Sciences Center, New Orleans, LA, 2000.

Residency: Rainbow Babies and Children's Hospital/ Case Western Reserve University, Cleveland, OH.

Certification: Pediatrics, 2003.

Awards and Honors

William Cooper Procter Scholar, 2006
PAS Young Investigator's Travel Award, 2005

Research

Environmental health; asthma; allergy; lead poisoning

Research Grants and Contracts

NIH
Exploratory/ Developmental Research Grant Award (R21)
Environmental Exposures, NOS Genes, and Exhaled Nitric Oxide in Pediatric Asthma
The aims of this grant are to determine the longitudinal relationship of environmental exposures with eNO levels over the 12 month study period; evaluate whether polymorphisms in NOS genes are associated with eNO levels as measured over the twelve month study period and whether environmental exposures modify this relationship; and determine the relationship of eNO levels and asthma severity over a 12 month period.
Role: Primary Investigator
July 15, 2006-June 30, 2009

Flight Attendant Medical Research Institute
Young Clinical Scientist Award
Low Level Prenatal Tobacco Exposure and Infant Wheeze
The aims of this career development grant are to 1) test which measure(s) of prenatal tobacco exposure is most strongly associated with wheeze episodes and respiratory infections in the first two years of life; and 2) investigate the association of maternal passive ETS exposure during pregnancy with the risk of wheeze episodes and respiratory infections in infant offspring, by evaluating exposures and risk of respiratory outcomes in infants born to mothers who did not smoke during pregnancy.
Role: Primary Investigator
July 1, 2007-June 30, 2010

ATSDR/EPA
Pediatric Environmental Health Specialty Units (PEHSU) – Region V Subcontract
This project establishes a collaborative between the Region V PEHSU and the Pediatric Environmental Health & Lead Clinic at Cincinnati Children’s Hospital Medical Center. The goal of the project is pediatric environmental health education and outreach for Ohio and adjoining areas of Region V to advance the mission of the PEHSU.
Role: Primary Investigator
8/01/07 – 7/31/08

Mentored Patient Oriented Research Career Development Award
NIEHS
Prenatal Low Level Tobacco & Phthalate Exposure & Childhood Respiratory Health
The aims of this career development grant are to 1) test which measure(s) of prenatal tobacco exposure is most strongly associated with wheeze, respiratory infections, and pulmonary inflammation in the first three years of life; 2) investigate the association of maternal passive tobacco smoke exposure during pregnancy with wheeze, respiratory infections, and pulmonary inflammation in the first three years of life in children born to mothers who did not smoke during pregnancy; and 3) investigate the association prenatal phthalate exposure with wheeze, respiratory infections, and pulmonary inflammation in the first three years of life.
Role: Primary Investigator
July 1, 2008 – June 30, 2013

Publications, Most Recent

Spanier AJ, Hornung R, Kahn R, Lierl M, Lanphear B. Seasonal Variation and Environmental Predictors of Exhaled Nitric Oxide in Tobacco Exposed Children with Asthma.Pediatric Pulmonology 2008;43(6):576-83.

Spanier, AJ, Hornung, R, Lierl, M, and Lanphear, B. Environmental Exposures and exhaled Nitric Oxide in Children with Asthma.The Journal of Pediatrics 2006;149(2):220-6.

Spanier, AJ and Lanphear, B. Current Best Evidence: Follow-up testing among children with elevated screening blood lead levels.The Journal of Pediatrics 2005;147(5):708-9.

Books

Contributing author, Occupational and Environmental Health: Recognizing and Preventing Disease and Injury (5th Edition), Barry Levy and David Wegman, Editors Sherry Baron and Rosie Sokas, Associate Editors, Lippincott Williams & Wilkins, 2006.

Editorial Positions

Public Health Reports, Contributing editor, Oct. 2004-Present

Presentations, Most Recent

Spanier AJ, Hornung R, Kahn R, Lierl M, and Lanphear BP. Seasonal Variation and Environmental Predictors of Exhaled Nitric Oxide in Children with Asthma. Oral Presentation at the annual pediatric environmental health scholars meeting, Dec 2007, Crystal City, VA.

Spanier AJ, Hornung R, Kahn R, Lierl M, and Lanphear BP. Seasonal Variation and Environmental Predictors of Exhaled Nitric Oxide in Children with Asthma. Oral presentation at the Pediatric Academic Societies meeting, Toronto, Canada, May 2007.

Spanier, AJ, Hornung, R, Kahn, R, Lierl M, and Lanphear, BP. Trends and Environmental Predictors of Exhaled Nitric Oxide in Children with Asthma. Oral Presentation at the annual pediatric environmental health scholars meeting, Dec 2006, Crystal City, VA.