Human Genetics

Derek Neilson, MD

Appointment

Assistant Professor, University of Cincinnati College of Medicine

Email

derek.neilson@cchmc.org

Phone

513-803-2412

Bio

Dr. Neilson studies genetic contributions to the disorder acute necrotizing encephalopathy (ANE), in which children are predisposed to devastating neurologic injury following common infections. Research involving families with recurrent ANE has revealed a candidate gene which is now being studied in mouse and cellular models.

Credentials

MD: Oregon Health Sciences University, 1998

BA: Biology, Johns Hopkins University, 1993

Research Grants and Contracts

K08 NS50331-01A1
NIH/NINDS
07/2005-06/2010
Genetic Mechanisms of Acute Necrotizing Encephalopathy.
Principal Investigator: Derek E. Neilson, MD

Publications, Most Recent

Izumi K, Curtis C, Christ L, Hahn A, Neilson DE. Familial Microduplication of 9q22.1. In preparation.

Neilson DE, Adams MD, Orr CMD, Schelling DK, Eiben RM, Kerr DS, Bye AM, Childs AM, Clarke A, Crow YC, Gika AD, Grattan-Smith PJ, Schmitt-Mechelke T, Uldall P ,van der Knaap MS, Trevarthen KC, Tefft DL, Warman ML. A recurrent mutation in a nuclear pore protein predisposes to acute necrotizing encephalopathy. Submitted 2008.

Falk, MJ, Feiler, HS, Neilson, DE, Maxwell, K, Lee, JV, Segall, SK, Robin, NH, Wilhelmsen, KC, Träskelin, A-L, Kolehmainen, J, Lehesjoki, A-E, Wiznitzer, M, Warman, ML. Cohen syndrome in the Ohio Amish.Am J Med Genet 2004;128A(1):23-8.

Neilson DE, Feiler HS, Wilhelmsen KC, Lynn A, Eiben RM, Kerr DS, Warman ML. Autosomal dominant acute necrotizing encephalopathy maps to 2q12.1-2q13.Ann Neurol 2004;55(2):291-294.

Neilson DE, Eiben RM, Waniewski S, Hoppel CL, Varnes ME, Bangert BA, Wiznitzer M, Warman ML, Kerr DS. Autosomal dominant acute necrotizing encephalopathy. Neurology 2003;61(2):226-30.

Neilson DE, Brunger JW, Heeger S, Bamshad M, Robin NH. Mixed clefting type in Rapp-Hodgkin syndrome.Am J Med Genet 2002;108(4):281-4.