Heart Institute

Thomas R. Kimball, MD

Title

Director, Echocardiography

Appointment

Professor of Pediatrics, University of Cincinnati College of Medicine

Email

tom.kimball@cchmc.org

Phone

513-636-8270

Fax

513-636-3952

Bio

Thomas R. Kimball, MD, is currently the director of Echocardiography and the director of the Cardiovascular Imaging Core Research Laboratory at Cincinnati Children's Hospital Medical Center.

A native of California, Dr. Kimball graduated with Distinction and Honors from Stanford University. He earned his medical degree from New York University, New York, NY.

Dr. Kimball completed his pediatric internship and residency at Children's Hospital of Los Angeles and his pediatric cardiology fellowship at Cincinnati Children's Hospital Medical Center.

Dr. Kimball has been an attending staff member of the Division of Cardiology at Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine since 1988. He became director of Echocardiography in 1998.

Dr. Kimball's academic interests relate to echocardiography and he has made numerous scholarly contributions in the field of ventricular function utilizing echocardiography, particularly in the field of hypertension and obesity.

Dr. Kimball has established collaborative relationships with basic scientists at the University of Cincinnati College of Medicine using echocardiography to evaluate phenotypes of transgenic mice, including embryonic mice.

Dr. Kimball has been active in the cardiology community. He is a member of the American Society of Echocardiography, American Heart Association, American Academy of Pediatrics, American College of Cardiology and an investigator in the NIH Pediatric Heart Network.

Dr. Kimball was also a member of the first Family Advisory Council at Cincinnati Children's and received the 2006 Family Advisory Council Award of Excellence.

Credentials

BS: Stanford University with Honors and Distinction, Stanford, CA, 1978.

MD: New York University School of Medicine, New York City, NY, 1982.

Residency: Pediatrics, Children's Hospital of Los Angeles, Los Angeles, CA, 1985.

Fellowship: Pediatric Cardiology, Children's Hospital Medical Center, Cincinnati, OH, 1988.

Certification: Pediatrics, 1986; Pediatric Cardiology, 1991 (recertification, 1997, 2004).

Awards and Honors

Nominee, American Society of Echocardiography Richard Popp Award – for contribution to education in echocardiography, 2004, 2005.
Nominee, American Society of Echocardiography Excellence-In-Teaching Award, 2006.
Family Advisory Council Award of Excellence in Family Centered Care, Cincinnati Children's Hospital Medical Center, 2006.
Best Doctors in America, 2008

Research

Ventricular function
Transgenic mice phenotyping
Cardiovascular changes with obstructive sleep apnea
Cardiovascular changes with renal disease
Pediatric obesity
Cardiovascular changes in fit and unfit children
Echocardiography quality assurance

Research Grants and Contracts

2001 - 2007: Principal Investigator, "Visceral Adiposity and CVD Risk in Women". National Institute of Health.

2002 - 2007: Mentor, "Cardiac Disease in Children with Chronic Renal Failure". National Institute of Health.

2003 - 2008: Co-Investigator, "Mechanisms Mediating Cardiac and Vascular Disease in Children with Obstructive Sleep Apnea". National Institute of Health.

2004 - 2007: Co-Investigator, "Wright State subcontract Longitudinal Cardiac Outcomes and Body Composition". National Institute of Health.

2004 - 2008: Co-Investigator, "SCCOR in Pediatric Heart Development and Disease Core B: Echocardiographic Studies of Valvular Heart Disease". National Institute of Health.

2005 - 2009: Principal Investigator, "CV Disease in Adolescents with Type 2 Diabetes". National Institute of Health.

Publications, Most Recent

Mitsnefes MM, Kimball TR, Kartal J, Witt SA, Glascock BJ, Khoury PR, Daniels SR. Progression of left ventricular hypertrophy in children with early chronic kidney disease: 2-year follow-up study. Journal of Pediatrics Nov 2006;149(5):671-675.

Carlo WF, Kimball TR, Michelfelder EC, Border WL. Persistent diastolic flow reversal in abdominal aortic Doppler-flow profiles is associated with an increased risk of necrotizing enterocolitis in term infants with congenital heart disease.Pediatrics 2007;119:330-335.

Border WL, Kimball TR, Witt SA, Glascock BJ, Khoury P, Daniels SR. Diastolic filling abnormalities in children with essential hypertension.Journal of Pediatrics 2007 May;150(5):503-9.

Ippisch H, Kimball T. The impact of evolving hand-carried echocardiographic technology on outpatient physical examination accuracy in pediatric cardiology. Congenital Heart Disease 2007 May;2(3):170-178.

Hao M, Ippisch HM, Cook RS, Perry DJ, Gottliebson WM, Hirsch R, Kimball TR. Implementation of an objective testing system in noninvasive cardiac imaging for evaluation of pediatric cardiology fellows. Journal of the American Society of Echocardiography 2007 Oct;20(10):1211-1218.

Amin R, Somers V, McConnell K, Willging P, Meyer C, Sherman M, McPhail G, Morgenthal A, Fenchel M, Bean J, Kimball TR, Daniels S. Activity-adjusted 24-hour ambulatory blood pressure and cardiac remodeling in children with sleep disordered breathing. Hypertension 2008 Jan;51:84-91.

Bigham MT, Brady PW, Manning PB, Jacobs BR, Kimball TR, Wong HR. Therapeutic application of intrapericardial tissue plasminogen activator in a 4-month-old child with complex fibropurulent pericarditis. Pediatric Critical Care Medicine 2008 Jan;9(1):e1-e9.

Weaver DJ Jr, Kimball TR, Knilans T, Mays W, Knecht SK, Gerdes YM, Witt S, Glascock BJ, Kartal J, Khoury P, Mitsnefes MM. Decreased maximal aerobic capacity in pediatric chronic kidney disease. J Am Soc Nephrol. 2008 Mar;19(3):624-30. Epub 2008 Jan 9.

Ippisch HM, Inge TH, Daniels SR, Wang B, Khoury PR, Witt SA, Glascock BJ, Garcia VF, Kimball TR. Reversibility of cardiac abnormalities in morbidly obese adolescents. Journal of the American College of Cardiology 2008 Apr;51 (14):1342-1348. Winner of the 2007 Parmley Prize awarded by the Editorial Board of the Journal of the American College of Cardiology for one of the two best, junior authored papers submitted for 2007. Also nominated as a finalist for the Sandra Daugherty Award for Excellence in Cardiovascular Disease by the American Heart Association in 2007.

Wisler J, Kimball TR, Khoury P. The effect of left ventricular size on right ventricular hemodynamics in pediatric survivors with hypoplastic left heart syndrome. Journal of the American Society of Echocardiography 2008 May;21(5):464-469.

Wilson AC, Urbina E, Witt SA, Glascock BJ, Kimball TR, Mitsnefes M. Flow-mediated vasodilatation of the brachial artery in children with chronic kidney disease. Pediatr Nephrol. 2008 Aug;23(3):1297-1302. Epub 2008 May 6.

Mulvagh SL, Rakowski H, Vannan M, Abdelmoneim SS, Becher H, Bierig SM, Burns PN, Castello R, Coon PD, Hagen ME, Jollis JG, Kimball TR, Kitzman DW, Kronzon I, Labovitz AJ, Lang RM, Mathew J, Moir WS, Nagueh SF, Pearlman AS, Perez JE, Porter TR, Rosenbloom J, Strachan GM, Thanigaraj S, Wei K, Woo A, Yu EH, Zoghbi WA. ASE Consensus Statement American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography. Journal of the American Society of Echocardiography 2008 Nov;21(11):1179-1201.

Urbina EM, Kimball TR, McCoy CE, Khoury PR, Daniels SR, Dolan LM. Youth with obesity and obesity-related Type 2 diabetes demonstrate abnormalities in carotid structure and function. To be published in Circulation 2009.

Presentations, Most Recent

Ippisch H, Inge T, Daniels S, Wang B, Khoury P, Witt S, Glascock B, Garcia V, Kimball T. Reversibility of cardiac abnormalities in extremely overweight adolescents. Presented at the 47th Annual Conference on Cardiovascular Disease Epidemiology and Prevention, February 28, 2007, Orlando, FL.

Jaworski JM, Khoury PR, Kimball TR. Adverse cardiovascular risk factors in children are related to early BMI rebound age. Accepted to the 56th Annual Scientific Sessions of the American College of Cardiology, New Orleans, LA, March 2007. (unable to present)

Witt S, Kimball TR, Secular Trends of Cardiovascular Risk Factors in Children According to Left Ventricular Mass and Body Mass Index: A Twenty Year Echocardiographic Study. Presented at the 56th Annual Scientific Sessions of the American College of Cardiology, New Orleans, LA, March 2007.

Sekar P, Border W, Kimball TR, Hirsch R, Manning PB, Beekman RH. Accuracy of cuff and echo Doppler blood pressure gradients to detect recurrent aortic arch obstruction in infants after the Norwood Stage I palliation. Presented at the 56th Annual Scientific Sessions of the American College of Cardiology, New Orleans, LA, March 2007

Gerdes YM, Knecht SK, Hambrook JT, Mays WA, Border WL, Kimball TR, Knilans TK. Decreased exercise capacity in patients with combined aortic and mitral stenosis versus isolated aortic stenosis. Presented at the American College of Sports Medicine Meeting, New Orleans, LA, June 2, 2007.

Hambrook JT, Border WL, Knecht SK, Mays WA, Knilans TK, Kimball TR. Effect on exercise of combined mild aortic and mitral stenosis: do the Bethesda exercise guidelines need reconsideration? Presented at the American Society of Echocardiography 18th Annual Scientific Sessions, Seattle, Washington, June17, 2007.

Border WL, Kimball TR. Impaired diastolic filling during exercise negatively impacts exercise capacity in children who have undergone the Fontan operation. Presented at the American Heart Association Scientific Sessions, Orlando, Florida, November 5, 2007.

Jaworski J, Kimball TR. Relationship of body mass index rebound age and adverse cardiovascular risk factors in children. Presented at the American Heart Association Scientific Sessions, Orlando, Florida, November 5, 2007.

Ippisch HM, Kimball TR. Abnormalities of left ventricular geometry in youth with type 2 diabetes: a greater effect of obesity than fasting glucose. Presented at the American Heart Association Scientific Sessions, Orlando, Florida, November 6, 2007.

Mays WA, Knecht SA, Gerdes YM, Moore V, Witt SA, Glascock BJ, Khoury P, Claytor RP, Hambrook JT, Michelfelder EC, Kimball TR, Knilans TK, Border WL. Evaluation of diastolic and systolic cardiac function in beta blocked pediatric patients using exercise echocardiography. Presented at the 55th Annual Meeting of The American College of Sports Medicine, Indianapolis, Indiana, May 28, 2008.

Knecht SK, Mays WA, Gerdes YM, Moore V, Witt SA, Glascock BJ, Claytor RP, Hambrook JT, Khoury P, Michelfelder EC, Kimball TR, Knilans TK, Border WL. Exercise evaluation of systolic cardiac function in single ventricle Fontan patients using tissue Doppler echocardiography. Presented at the 55th Annual Meeting of The American College of Sports Medicine, Indianapolis, Indiana, May 28, 2008.

Gerdes YM, Knecht SK, Mays WA, Moore V, Witt SA, Glascock BJ, Claytor RP, Hambrook JT, Koury P, Michelfelder EC, Kimball TR, Knilans TK, Border WL. Evaluation of systemic vascular resistance in single ventricle Fontan patients using exercise echocardiography. Presented at the 55th Annual Meeting of The American College of Sports Medicine, Indianapolis, Indiana, May 28, 2008.

Urbina EM, Kimball TR, McCoy CE, Khoury PR, Daniels SR, Dolan LM. Youth with obesity and type 2 diabetes demonstrate abnormalities in carotid structural and function. Presented at the 68th Scientific Sessions of the American Diabetes Association, San Francisco, California, June 6-10, 2008.

Shah A, Dolan LM, Khoury PR, Kimball TR, Daniels SR, Urbina EM. Carotid intimal wall thickness: the influence of glycemic control, duration and gender in youth with type 2 diabetes. Presented at the 68th Scientific Sessions of the American Diabetes Association, San Francisco, California, June 6-10, 2008.

Behrman M, Rumpke H, Kimball TR. Expanding patient care delivery and community access through remote tele-echocardiography. Presented at the NACHRI 2008 Annual Meeting, Salt Lake City, UT, October 14-17, 2008.

Shah A, Urbina EM, Kimball TR Dolan LM, Daniels SR. Cardiovascular risk assessment: successful identification of sub-clinical vascular disease in healthy youth. Presented at the American Heart Association Joint Conference 49th Cardiovascular Disease Epidemiology and Prevention –and- Nutrition, Physical Activity and Metabolism, Palm Harbor, Florida, March 12, 2009.

McCoy CE, Khoury PR Dolan LM, Daniels SR, Kimball TR, Urbina EM. Carotid intima-media thickness in youth has a stronger relationship with body mass than with body fat as measured by dual x-ray absorptiometry. Presented at the American Heart Association Joint Conference 49th Cardiovascular Disease Epidemiology and Prevention –and- Nutrition, Physical Activity and Metabolism, Palm Harbor, Florida, March 12, 2009.