Dingding Xiong, MD, PhD
Title
Fellow of Pediatric Cardiology
Email
dingding.xiong@cchmc.org
Phone
513-636-6647
Bio
Xiong received his Medical Degree from Jiangxi Medical College in China in 1987. After completing a residency program in Internal Medicine followed by a fellowship in Cardiology at the same medical school, he went on to become an attending physician in cardiology in China.
He received his PhD in cardiology at Zhangshan Hospital, Shanghai Medical University, which led to a research career in cardiomyopathy and heart failure.
While working in Kirk U. Knowlton's lab in the Division of Cardiology at University of California, San Diego, Xiong led a research effort to understand the molecular mechanisms responsible for enterovirus-induced cardiomyopathy and the role of the coxsackievirus and adenovirus receptor (CAR) in cardiovascular development.
Currently he is a pediatric fellow in the Heart Institute.
Credentials
MD: Jiangxi Medical College, P.R. China, 1987
Residency: Pediatrics, Driscoll Children’s Hospital, Corpus Christi, TX
Certification: Pediatrics, 2009
Research
Molecular mechanism of myocarditis and cardiomyopathy
Publications, Most Recent
Lim BK, Xiong D, Dorner A, Youn TJ, Yung A, Liu TI, Gu Y, Dalton ND, Wright AT, Evans SM, Chen J, Peterson KL, McCulloch AD, Yajima T, Knowlton KU: Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest. 2008 Aug;118(8):2758-70.
Xiong D, Yajima T, Lim BK, Stenbit A, Dublin A, Dalton ND, Summers-Torres D, Molkentin JD, Duplain H, Wessely R, Chen J, Knowlton KU: Inducible cardiac-restricted expression of enteroviral protease 2A is sufficient to induce dilated cardiomyopathy. Circulation. 2007 Jan 2;115(1):94-102.
Yajima T, Yasukawa H, Jeon ES, Xiong D, Dorner A, Iwatate M, Nara M, Zhou H, Summers-Torres D, Hoshijima M, Chien KR, Yoshimura A, Knowlton KU: Innate defense mechanism against virus infection within the cardiac myocyte requiring gp130-STAT3 signaling. Circulation. 2006 Nov 28;114(22):2364-73.
Special Interests
Diagnosis and treatment of congenital heart disease and myocarditis/cardiomyopathy
