Hematology / Oncology

Stella M. Davies, MBBS, PhD, MRCP

Title

Director of Blood and Marrow Transplant Program, Jacob G. Schmidlapp Endowed Chair

Appointment

Professor of Pediatrics

Email

stella.davies@cchmc.org

Phone

513-636-2469

Fax

513-636-3549

Credentials

MBBS with First Class Honors: University of Newcastle-Upon-Tyne, England, 1981.

Clinical and Fellowship Training: The Royal Victoria Infirmary, Newcastle General Hospital and Great Ormond St. Hospital, 1981 to 1985.

PhD: Molecular Biology, University of Newcastle-Upon-Tyne, England, 1989.

Pediatric Fellowship: Hematology / Oncology and Bone Marrow Transplantation, University of Minnesota, Minneapolis, MN, 1989 to 1993.

Awards and Honors

Best Doctors in America, 2008
Awarded "2005 Best Doctors"
Awarded "2004 Best Doctors"
Elected at large member, Children's Oncology Group executive committee, 2000
Vice Chair, Epidemiology, NCI Progress Review Group, Leukemia, Lymphoma, Myeloma, 2000
Children's Cancer Group Clinical Science Junior Faculty Award, 1997
McQuarrie Research Award, University of Minnesota, 1996
American Society of Clinical Oncology Career Development Award, 1995
American Society of Pediatric Hematology and Oncology Young Investigator Award, 1993
American Society of Hematology Travel Award, 1992 and 1993
Undergraduate Special Research Study Prize, 1981
Goyder Scholarship for Clinical Medicine and Surgery, 1981
McNaughton Prize for Best Female Graduate, University of Newcastle-Upon-Tyne, 1981
Phillipson Prize for Best Graduate, University of Newcastle-Upon-Tyne, 1981
Dickinson Prize for Surgery, 1981
Mary Gordon Bursary Award, 1980

Research

Connect to Stella Davies' Laboratory Web Site

Research Grants and Contracts

R01CA93552-01 (Davies) 12/01/01-11/30/06 NIH NCI
Host factors and etiology of leukemia

U01 CA55727- (Robison) 5/31/04-5/31/10 NIH NCI
Molecular Genetics in Childhood Cancer Survivors

R01 CA79940-01A1 (Ross) 04/01/04 – 03/31/07 NIH/NCI
Epidemiology of Infant Leukemia

R01 CA111778 (Perentesis) 01/01/05-12/31/09 NIH
Molecular Studies of Down Syndrome Leukemia

R01 CA107143-01A1 (Ross) 04/01/05-03/31/10 NCI/NIH
Predictors of Adult Leukemia

Translational Research Initiative (Geiger) 07/01/05-06/30/06 Cincinnati Children's Hospital
Somatic Mutation Frequency Core

Translational Research Initiative 07/01/05-06/30/06 Cincinnati Children's Hospital
Etanercept in children with Fanconi Anemia

Publications, Most Recent

Connect to Stella Davies' Publications on PubMed

Hochhausen N, Altmaier EM, McQuellon R, Davies SM, Papadopolous E, Carter S, Henslee-Downey J. Social support, optimism, and self-efficacy predict physical and emotional well-being after bone marrow transplantation.J Psychosoc Oncol. 2007;25(1):87-101.

Mehta, PA, Eapen M, Klein JP, Gandham S, Elliott J, Zamzow T, Combs M, Aplenc R, MacMillan ML, Weisdorf DJ, Petersdorf E and Davies SM. Interleukin-1 alpha Genotype and Outcome of Unrelated Donor Haematopoietic Stem Cell Transplantation for Chronic Myeloid Leukaemia.British Journal of Haematology; 2007 Apr;137(2):152-7.

Spector LG, Davies SM, Robison LL, Hilden JM, Roesler M, Ross JA. Birth Characteristics, Maternal Reproductive History, and the Risk of Infant Leukemia: A Report from the Children's OncologyGroup.Cancer Epidemiol Biomarkers Prev. 2007 16:128-134.

Farzin A, Davies SM, Smith FO, Filipovich AH, Hansen M, Auerbach AD, Harris RE. Matched sibling donor transplant for Fanconi Anemia: an update of the Cincinnati Children's experience.British Journal of Hematology. 2007 Feb;136(4):633-40.

Wade JA, Hurley CK, Takemoto SK, Thompson J, Davies SM, Fuller TC, Rodey G, Confer DL, Noreen H, Haagenson M, Kan F, Klein J, Eapen M, Spellman S, Kollman C. HLA matching within or outside of cross-reactive groups (CREG) is associated with similar outcomes after unrelated stem cell transplant.Blood 2007, epub ahead of print.

Kelly PF, Radtke S, Kall C Balcik B, Bohn K, Mueller R, Schuesler T, Haren M, Reeves L, Cancelas JA, Leemhuis T, Harris RH, Auerbach AD, Smith FO, Davies SM, Williams DA. Stem cell collection and gene therapy in Fanconi anemia.Molecular Therapy, 2007:15:211-219.

Rao A , Kamani N, Filipovich A, Lee SM, Davies SM, Dalal J, and Shenoy Successful bone marrow transplantation for IPEX syndrome following reduced intensity conditioning.Blood, 2007 109:383-385.

Farag SS, Bacigalupo A, Eapen M, Hurley C, Dupont B, Caligiuri MA, Boudreau C, Nelson G, Oudshoorn M, van Rood J, Velardi A, Maiers M, Setterholm M, Confer D, Posch PE, Anasetti C, Kamani N, Miller JS, Weisdorf D, Davies SM; KIR Study Group, Center for International Blood and Marrow Transplantation Research. The Effect of KIR Ligand Incompatibility on the Outcome of Unrelated Donor Transplantation: A Report from the Center for International Blood and Marrow Transplant Research, the European Blood and Marrow Transplant Registry, and the Dutch Registry.Biol Blood Marrow Transplant. 2006 Aug;12(8):876-84

Mehta PA, Davies SM, Kumar A, Devidas M, Lee S, Zamzow T, Elliott J, Villanueva J, Pullen J, Zewge Y, Filipovich A. Perforin polymorphism A91V and susceptibility to B-precursor childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.Leukemia. 2006 20:1539-1541.

Altmaier EM, Ewell M, McQuellon R, Geller N, Carter SL, Henslee-Downey J, Davies S, Papadopoulos E, Yanovich S, Gingrich R. The effect of unrelated donor marrow transplantation on health-related quality of life: a report of the unrelated donor marrow transplantation trial (T-cell depletion trial).Biol Blood Marrow Transplant. 2006 Jun;12(6):648-55.

Su Y, Davies S, Davis M, Lu H, Giller R, Krailo M, Cai Q, Robison L, Shu XO.
Expression of LINE-1 p40 protein in pediatric malignant germ cell tumors and its association with clinicopathological parameters: A report from the Children's Oncology Group.Cancer Lett. 2006Epub ahead of print]

Geiger H, Schleimer D, Nattamai KJ, Dannenmann SR, Davies SM, Weiss BD. Mutagenic potential of temozolomide in bone marrow cells in vivo.Blood. 2006;107(7):3010-1.

Aplenc R, Alonzo TA, Gerbing RB, Smith FO, Meschinchi S, Ross JA, Perentesis J, Woods WG, Lange BJ and Davies SM. Ethnicity and survival in childhood acute myeloid leukemia: a report from the Children's Oncology Group.Blood, 2006 108:74-80.

Farag SS, Bacigalupo A, Eapen M, Hurley C, Dupont B, Caligiuri MA, Boudreau C, Nelson G, Oudshoorn M, van Rood J, Velardi A, Maiers M, Setterholm M, Confer D, Posch PE, Anasetti C, Kamani N, Miller JS, Weisdorf D, Davies SM; KIR Study Group, Center for International Blood and Marrow Transplantation Research. The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: a report from the center for international blood and marrow transplant research, the European blood and marrow transplant registry, and the Dutch registry.Biol Blood Marrow Transplant. 2006 Aug;12(8):876-84.

Mehta P, Ileri T, Harris RE, Williams DA, Mo J, Smolarek T, Kelly P and Davies SM Chemotherapy for myeloid malignancy in children with Fanconi Anemia. Pediatric Blood and Cancer, 2006 epub ahead of print.

Eapen M, Raetz E, Zhang MJ, Muehlenbein C, Devidas M, Abshire T, Billett A, Homans A, Camitta C, Carroll WL and Davies SM. Outcomes after HLA-matched sibling transplants or chemotherapy in children with B-precursor acute lymphoblastic leukemia in a second remission: a collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research.Blood, 2006, 107: 4961-4967.

Mehta P, Vinks A, Filipovich A, Vaughn G, Fearing D, Sper C, Davies SM. High-Dose Weekly AmBisome Antifungal Prophylaxis in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation: A Pharmacokinetic study.Biol Blood Marrow Transplant. 2006 Feb;12(2):235-40.

Shankar S, Davies SM, Giller R, Krailo M, Davis M, Gardner K, Cai H, Robison L, Shu XO. In utero exposure to female hormones and germ cell tumors in children.Cancer. 2006 Jan 18; [Epub ahead of print].

Eapen M, Rubinstein P, Zhang MJ, Camitta BM, Stevens C, Cairo MS, Davies SM, Doyle JJ, Kurtzberg J, Pulsipher MA, Ortega JJ, Scaradavou A, Horowitz MM, Wagner JE. Comparable long-term survival after unrelated and HLA-matched sibling donor hematopoietic stem cell transplantations for acute leukemia in children younger than 18 months. J Clin Oncol. 2006 Jan 1;24(1):145-51.

Shankar S, Davies S, Giller R, Krailo M, Davis M, Gardner K, Cai H, Robison L, Shu XO. In utero exposure to female hormones and germ cell tumors in children. Cancer. 2006 Jan 18;.

Mehta P, Vinks A, Filipovich A, Vaughn G, Fearing D, Sper C, Davies S. High-Dose Weekly AmBisome Antifungal Prophylaxis in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation: A Pharmacokinetic study. Biol Blood Marrow Transplant. 2006 Feb;12(2):235-40.

Mehta P, Ileri T, Harris RE, Williams DA, Mo J, Smolarek T, Kelly P and Davies SM. Chemotherapy for myeloid malignancy in children with Fanconi Anemia. Pediatric Blood and Cancer, 2006 Apr 11.

Geiger H, Schleimer D, Nattamai KJ, Dannenmann SR, Davies SM, Weiss BD. Mutagenic potential of temozolomide in bone marrow cells in vivo. Blood. 2006;107(7):3010-1.

Su Y, Davies S, Davis M, Lu H, Giller R, Krailo M, Cai Q, Robison L, Shu XO. Expression of LINE-1 p40 protein in pediatric malignant germ cell tumors and its association with clinicopathological parameters: A report from the Children's Oncology Group. Cancer Lett. 2006.

Altmaier EM, Ewell M, McQuellon R, Geller N, Carter SL, Henslee-Downey J, Davies S, Papadopoulos E, Yanovich S, Gingrich R. The effect of unrelated donor marrow transplantation on health-related quality of life: a report of the unrelated donor marrow transplantation trial (T-cell depletion trial). Biol Blood Marrow Transplant. 2006 Jun;12(6):648-55.

Farag SS, Bacigalupo A, Eapen M, Hurley C, Dupont B, Caligiuri MA, Boudreau C, Nelson G, Oudshoorn M, van Rood J, Velardi A, Maiers M, Setterholm M, Confer D, Posch PE, Anasetti C, Kamani N, Miller JS, Weisdorf D, Davies SM; KIR Study Group, Center for International Blood and Marrow Transplantation Research. The Effect of KIR Ligand Incompatibility on the Outcome of Unrelated Donor Transplantation: A Report from the Center for International Blood and Marrow Transplant Research, the European Blood and Marrow Transplant Registry, and the Dutch Registry. Biol Blood Marrow Transplant. 2006 Aug;12(8):876-84.

Chen Z, Stewart PA, Davies S, Giller R, Krailo M, Davis M, Robison L, Shu XO. Parental Occupational Exposure to Pesticides and Childhood Germ-Cell Tumors.Am J Epidemiol. 2005 Nov 1;162(9):858-67.

Davies SM, Radloff GA, DeFor TE, Levran O, Batish SD, Hanenberg H and AD Auerbach. GST Genotype May Modify Clinical Phenotype in Patients with Fanconi anemia (FA).Br J Haematol. 2005 Oct;131(1):118-22.

Spector LG, Xie Y, Robison LL, Heerema NA, Hilden JM, Lange B, Felix CA, Davies SM, Slavin J, Potter JD, Blair CK, Reaman GH, Ross JA. Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis; a report from the Children's Oncology group. Cancer Epidemiol Biomarkers Prev. 2005 Mar;14(3):651-5.

Chen Z, Robison L, Giller R, Krailo M, Davis M, Gardner K, Davies SM, Shu XO. Risk of childhood germ cell tumors in association with parental smoking and drinking.Cancer. 2005 Mar 1;103(5):1064-71.

Mehta PA, Davies SM. Pharmacogenetics of acute lymphoblastic leukemia.Curr Opin Hematol. 2004 Nov;11(6):434-8. Review.

Davies SM. Susceptibility to cancer: why did this happen to my child?Pediatr Blood Cancer. 2004 Oct;43(5):536-8.

Mertens AC, Mitby PA, Radloff G, Jones IM, Perentesis J, Kiffmeyer WR, Neglia JP, Meadows A, Potter JD, Friedman D, Yasui Y, Robison LL, Davies SM. XRCC1 and glutathione-S-transferase gene polymorphisms and susceptibility to radiotherapy-related malignancies in survivors of Hodgkin disease.Cancer. 2004 Sep 15;101(6):1463-72.

Chakraborty A, Lazova R, Davies S, Backvall H, Ponten F, Brash D, Pawelek J. Donor DNA in a renal cell carcinoma metastasis from a bone marrow transplant recipient.Bone Marrow Transplant. 2004 Jul;34(2):183-6.

Ross JA, Davies SM. Recent report in the etiology of childhood cancer: 'greatest hits'.Pediatr Blood Cancer. 2004 Jan;42(1):3-7.

Ross JA, Oeffinger K, Davies SM, Mertens AC, Langer EK Kiffmeyer WR, Sklar CA, Stovall M, Yasui Y, Robison LR. Genetic variation in the leptin receptor gene and obesity in survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2004 Sep 1;22(17):3558-62.

Grewal SS, Schapiro EG, Krivit W Charnas L Lockman LL, Delaney KA, Davies SM, Wenger DA, Rimmell FL,Abel S, Grovas AC, Orchard PJ, Wagner JE, Peters C. Effective treatment of alpha-mannosidosis by allogeneic hematopoietic stem cell transplantation.J Pediatr. 2004 May;144(5):569-73.

Kiffmeyer WR, Langer E, Davies SM, Envall J, Robison LL, Ross JA. Genetic polymorphisms in the Hmong population: implications for cancer etiology and survival.Cancer. 2004 Jan 15;100(2):411-7.

Keen LJ, DeFor TE, Bidwell J, Davies SM, Bradley BA, Hows JM. Interleukin-10 and tumor necrosis factor alpha region haplotypes predict transplant-related mortality after unrelated donor stem cell transplantation.Blood. 2004 May 1;103(9):3599-602.