Ming Tan, PhD
Appointment
Instructor
Email
ming.tan@cchmc.org
Phone
513-636-0510
Fax
513-636-7655
Credentials
PhD University of Münster, Münster, Germany, 1997
Position History
Instructor, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2005-present
Research associate, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2002-2005
Research fellow, University of Cincinnati, Cincinnati, Ohio, 2000-2002
Postdoctoral fellow, University of Nebraska at Lincoln, Nebraska, 1999-2000
Research scientist, University of Münster, Münster, Germany, 1997-1999
Research
Noroviruses
Human Caliciviruses
Viral Gastroenteritis
Research Grants and Contracts
Translational Research Initiative (Cincinnati Children's Hospital Medical Center)
"Characterization of norovirus P particle as a candidate of antiviral and vaccine against noroviruses"
Principal Investigator
07/2006-06/2007
Publications, Most Recent
Tan M, Farkas T, Jiang X. (2008) Molecular Pathogenesis of Human Norovirus. In: Host Gene Responses to RNA Virus Infection. Yang DC (Eds), World Scientific, Singapore: in press.
Farkas T, Tan M, Jiang X. (2008) Norovirus gastroenteritis. P39-52, In: Emerging Infections 8. Scheld WM, Hammer SW, Hughes JM. (Eds). ASM press, Washington, DC, USA: In press.
Tan M, Jiang X. (2008) The association of histo-blood group antigens with susceptibility to norovirus infection may be strain-specific, instead of genogroup-depedent. Journal of Infectious Diseases, 198: in press.
Bu WM, Mamedova A, Tan M, Xia M, Jiang X, Hegde RS. (2008) Structural basis for the receptor binding specificity of the Norwalk virus. Journal of Virology, 82:5340-5347.
Tan M, Jin M, Duan ZJ, Jiang X, Fang ZY. (2008) Outbreak studies of a GII-3 and a GII-4 norovirus revealed an association between HBGA phenotypes and viral infection. Journal of Medical Virology. 80:1296-1301.
Tan M, Jiang X. (2008) Norovirus gastroenteritis, increased understanding and future antiviral options. Current Opinion in Investigational Drugs. 9: 146-151.
Tan M, Jiang X. (2007) Norovirus-host interaction: implications for disease control and prevention. Expert Review in Molecular Medicine. 9:1-22.
Cao S, Lou ZY, Tan M, Chen YT, Liu YJ, Zhang ZS, Zhang XJ, Jiang X, Li XM, Rao ZH. (2007) Structural basis for specific recognition of blood group trisaccharides by norovirus. Journal of Virology. 81: 5949-5957.
Tan M, Sun XJ, Jiang X. (2006) Norovirus gastroenteritis: New strategies of control and prevention. Touch Briefings: US Special Population Pediatrics Reviews. 2006 Issue 2: 21-24.
Tan M, Meller J, Jiang X. (2006). C-terminal arginine cluster is essential for receptor-binding of norovirus capsid protein. Journal of Virology. 80: 7322-7331.
Tan M, Jiang X (2005). The P domain of Norovirus capsid protein forms subviral particles that bind to histo-blood group antigen receptors.Journal of Virology. 79: 14017-14030.
Tan M, Jiang X (2005). Norovirus and its histo-blood group antigen receptors: an answer to a historical puzzle.Trends in Microbiology. 13: 285-293.
Tan M, Zhong W, Song D, Thornton S, Jiang X. (2004). The E. Coli-expressed recombinant norovirus capsid proteins maintain authentic antigenicity and receptor binding capability.Journal of Medical Virology. 74: 641-649.
Tan M, Hegde R, Jiang X (2004). The P domain of Norovirus capsid protein forms dimer and binds to histo-blood group antigen receptors.Journal of Virology. 78: 6233-6242.
Professional Organization Memberships
American Society for Virology
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical Center:
