Bradley P. Dixon, MD
Appointment
Research Assistant Professor of Pediatrics, University of Cincinnati College of Medicine
Email
bradley.dixon@cchmc.org
Phone
513-636-4531
Fax
513-636-7407
Credentials
BA: College of Wooster, Wooster, OH, 1995.
MD: University of Tennessee, Memphis, 1999.
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 1999-2002.
Chief Residency: Pediatrics, Cincinnati Childrens Hospital, 2002-2003.
Fellowship: Pediatric Nephrology and Hypertension, Cincinnati Childrens Hospital, 2003-2006.
Awards and Honors
- Departmental & Independent Study Thesis Honors, Chemistry, 1995
- Phi Beta Kappa, 1995
- William Z. Bennett Prize in Chemistry, 1995
- Alpha Omega Alpha, 1998
- Fellow Teacher of the Year Award, 2005
- William Cooper Procter Pediatric Research Award, 2006
Research
DNA damage and repair
Research Grants and Contracts
DNA Damage and Repair in Augmentation Cystoplasty
William Cooper Procter Pediatric Research Award
PI Bradley P. Dixon, MD
Dates 7/1/06-6/30/09
Goal To characterize the effects of a hyperosmolar bladder microenvironment in a cell culture and animal model of augmentation cystoplasty.
DNA Damage and Malignancy of the Pediatric Neobladder
Kidney Foundation of Greater Cincinnati Research Grant
PI Bradley P. Dixon, M.D.
Dates 7/1/06-6/30/07
Goal To assess the genotoxic effect of the bladder environment on the development of proliferative lesions in augmentation cystoplasty.
Recognition and Repair of DNA Damage in the Augmented Bladder
Pediatric Research Loan Repayment Program – NIH/NIDDK
PI Bradley P. Dixon, M.D.
Dates 7/1/09-6/30/11
Goal To characterize the DNA damage identification and repair of conditionally immortalized primary cell lines of gastric, ileal, and colonic as well as transitional origin under hyperosmolar conditions.
Child Health Research Career Development Award (NIH 2 K12 HD028827 Year 18)
Project Title: Pediatric Center for Gene Expression and Development
CCHMC PI: Dr. Arnold Strauss. Program Director: Dr. Marc Rothenberg
Awardee: Bradley P. Dixon, M.D.
Dates 7/01/09-6/30/10 (Year 1)
Goal To study the effect of osmotic stress on the DNAdamage identification and repair ofconditionally immortalized primary cell lines of gastrointestinal as well as transitional epithelium origin.
Publications, Most Recent
- Bissler JJ, Dixon BP. A mechanistic approach to inherited polycystic kidney disease.Pediatr Nephrol 2005;20(5):558-566.
- Dixon BP, Devarajan P, Mitsnefes M. Neonatal renovascular hypertension due to prenatal traumatic retroperitoneal hematoma.Pediatr Nephrol 2005;20(5):670-672.
- Dixon BP, McEnery P, Goebel J. Immunobiology of paediatric renal transplantation.Progress in Paediatric Urology 2008; 10:165-182.
- Dixon BP, Lu L, Chu A, Bissler JJ. RecQ and RecG Helicases Have Distinct Roles in Maintaining the Stability of Polypurine•Polypyrimidine Sequences. Mutation Research 2008 Aug 25; 643(1-2):20-8.
- Dixon BP, Chu A, Henry J, Kim R, Bissler JJ. Increased cancer risk of augmentation cystoplasty: possible role for hyperosmolal microenvironment on DNA damage recognition.Mutation Research. Epub July 30 2009.
Professional Organization Memberships
- Diplomate, American Board of Pediatrics, 2002.
- Diplomate, American Board of Pediatrics, Subboard of Pediatric Nephrology, 2008.
- Fellow, American Academy of Pediatrics, 2003.
- Active Member, American Society of Nephrology, 2006.
- Active Member, American Society of Pediatric Nephrology, 2006.
- Board member, Cincinnati Pediatric Society, 2007.
Special Interests
Polycystic kidney disease; biology of bladder augmentation
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical
Center: