The Surgical Weight Loss Program for Teens at Cincinnati Children's Hospital Medical Center is actively involved in research related to weight loss surgery. Current projects include:
Previous Research and Publications
Inge TH, Zeller M, Harmon C, Helmrath M, Bean J, Modi A, Horlick M, Kalra M, Xanthakos S, Miller R, Akers R, Courcoulas A. Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgery. J Pediatr Surg. 2007 Nov;42(11):1969-71.
Miller RJ, Xanthakos SA, Hillard PJ, Inge TH. Bariatric surgery and adolescent gynecology. Curr Opin Obstet Gynecol. 2007 Oct;19(5):427-33.
Helmut R. Roehrig, PhD, Stavra A. Xanthakos, MD, Jenny Sweeney, RN, MSN, CPNP, Meg H. Zeller, PhD, Thomas H. Inge, MD, PhD. Pregnancy After Gastric By-Pass Surgery in Adolescents. Obesity Surgery, 17:873-877, 2007
Thomas H. Inge, Paul Pfluger, Meg Zeller, Susan R. Rose, Lukas Burget, Sumana Sundararajan, Stephen R. Daniels and Matthias H. Tschöp. Gastric Bypass for Treatment of Hypothalamic Obesity after Craniopharyngioma Therapy. Nature Clinical Practice Endocrinology and Metabolism 2007 Aug;3(8):606-9.
Christopher M. Tangren, Linda Cripe, Robert H. Beekman, III, and Thomas H. Inge. Gastric bypass and balloon valvuloplasty in the management of critical aortic stenosis in a morbidly obese adolescent. Journal of. Pediatric Surgery 2007 Aug;42(8):1443-5.
Thomas H. Inge, Kimberly Wilson, Kim Gamm, Shelley Kirk, Victor F. Garcia, Stephen R. Daniels. Preferential Loss of Central (Trunk) Adiposity in Adolescents after Laparoscopic Gastric Bypass. Surgery for Obesity and Related Metabolic Diseases 2007 Mar-Apr;3(2):153-8.
Tsai WS, Inge TH, Burd RS. Bariatric surgery in adolescents: recent national trends in use and in-hospital outcome. Archives of Pediatric and Adolescent Medicine. 2007 Mar;161(3):217-21.
Xanthakos SA, Inge TH. Extreme pediatric obesity: weighing the health dangers. J Pediatr. 2007 Jan;150(1):3-5.
Inge TH, Xanthakos SA, Zeller MH. Bariatric surgery for pediatric extreme obesity: now or later? Int J Obes (Lond). 2007 Jan;31(1):1-14.
Xanthakos SA, Daniels SR, Inge TH. Bariatric surgery in adolescents: an update. Adolesc Med Clin 17(3):589-612; 2006.
Kalra M, Inge T. Effect of bariatric surgery on obstructive sleep apnea in adolescents. Paediatr Respir Rev. 2006 Dec;7(4):260-7.
Inge TH: Bariatric surgery for morbidly obese adolescents: Is there a rationale for early intervention? Growth Hormone & IGF Research 2006 May 2006 Jul;16S:15-19
Xanthakos S, Inge T: Nutritional Consequences of Bariatric Surgery. Current Opinion in Clinical Nutrition and Metabolic Care. 2006 9(4):489-496
Helmrath MA, Brandt ML, Inge TH: Adolescent obesity and bariatric surgery. Surg Clin North Am. 2006 Apr;86(2):441-54.
Meg H. Zeller, Helmut R. Roehrig, Avani C. Modi, Stephen R. Daniels, Thomas H. Inge: Adolescents Seeking Bariatric Surgery: An Examination of Health-Related Quality of Life and Depressive Symptoms. Pediatrics 2006 Apr;117(4):1155-61.
Lawson L, Harmon C, Chen M, Loux T, Kirk S, Garcia V, Daniels S, Inge T: One-Year Outcomes of Roux en Y Gastric Bypass in Adolescents: A multicenter report from the Pediatric Bariatric Study Group. Journal of Pediatric Surgery, 2006. 41(1):137-43; discussion 137-43.
This paper is the first multicenter study providing a detailed description of metabolic changes seen in adolescents undergoing laparoscopic gastric bypass at pediatric medical centers.
Xanthakos S, Miles L, Bucuvalas J, Daniels S, Garcia V, Inge T: Histologic Spectrum of NASH in Morbidly Obese Adolescents Differs from Adults. Clinical Gastroenterology and Hepatology, 2006 Feb;4(2):226-32.
Kalra M, Inge T, Garcia V, Daniels S, Lawson L, Curti B, Cohen A, Amin R: Obstructive Sleep Apnea in Morbidly Obese Adolescents: Effect of Bariatric Surgical Intervention. Obesity Research, 2005; 13:1175-1179.
This paper is the first description of baseline severity of obstructive sleep apnea in morbidly obese teenagers and the dramatic response to surgical weight loss.
Kirk S, Inge TH, Daniels SR: Gastric Bypass Surgery for Severely Obese Adolescents: Nutritional Considerations. Pediatric Nutrition -- A Building Block for Life, a Publication of the Pediatric Nutrition Proactice Group, American Dietetics Association, Volume 24; No. 4, Fall 2005.
Allen S, Lawson L, Garcia V, Inge T: Attitudes of ASBS members concerning adolescent bariatric surgery. Obesity Surgery, 2005; Sep;15(8):1192-5.
Inge TH, Zeller M, Lawson L, Daniels SR: Critical Appraisal of the Evidence Supporting Bariatric Surgery for Weight Management in Adolescence. Journal of Pediatrics, 2005. 147(1):10-19.
This paper discusses the important scientific evidence justifying consideration of bariatric surgery for adolescents and outlines important research issues for younger patients.
Inge TH, Lawson L: Treatment Considerations for Severe Adolescent Obesity, Surgery for Obesity and Related Metabolic Diseases. 2005 1:133-139.
This paper succinctly reviews our current understanding of the challenges facing physicians who are engaged in treatment of severely obese adolescents.
Inge TH, Donnelly LF, Vierra M, Cohen A, Daniels SR, Garcia VF: Managing Bariatric Patients In a Children's Hospital: Radiologic Considerations and Limitations. Journal of Pediatric Surgery, 2005; 40:609-617.
Inge TH, Zeller M, Garcia V, Daniels S: Surgical Approach to Adolescent Severe Obesity. Adolescent Medicine Clinics, 2004; 15:429-453.
This paper presents an overview of adolescent bariatric patient management considerations for practicing pediatricians.
Towbin A, Inge TH, Garcia VF, Roerig HR, Clements RH, Harmon CM, Daniels SR: Beriberi after gastric bypass surgery. Journal of Pediatrics, 2004; 145(2):263-267.
This paper discusses the risks of thiamine deficiency after adolescent bariatric surgery.
Inge T, Krebs N, Garcia V, Skelton J, Guice K, Strauss R, Albanese C, Brandt M, Donovan E, Hammer L, Harmon C, Kane T, Klish W, Oldham K, Rudolph C, Daniels S: Bariatric Surgery for Severely Overweight Adolescents: Concerns and Recommendations. Pediatrics, 2004; 114: 217-223.
This paper authored by a group of experts for the first time discusses special guidelines for use of bariatric surgery in the adolescent population.
Inge TH, Garcia VF, Daniels SR, et al: A Multidisciplinary Approach to the Adolescent Bariatric Surgical Patient. Journal of Pediatric Surgery, 2004; 39:442-447.
This paper establishes guidelines for pediatric institutional preparations necessary for adolescent bariatric surgical program development.
Garcia VF, Langford L, Inge TH: Application of Laparoscopy for Bariatric Surgery in Adolescents. Current Opinions in Pediatrics 2003; 15:248-255.
This paper discusses the importance of minimally invasive approaches to adolescent bariatric surgery.