Find a Health Care Professional / Researcher

Ardythe L. Morrow, PhD

Title

Director

Appointment

Professor, University of Cincinnati College of Medicine

Email

ardythe.morrow@cchmc.org

Phone

513-636-7584

Fax

513-636-7509

Bio

Dr. Morrow received her MSc in nutrition from the University of the West Indies, Kingston, Jamaica (1980) and PhD in epidemiology from the University of Texas at Houston (1991). Since 1987 she has worked with colleagues in Mexico, Boston, and Houston on an NIH-funded program project on human milk immune protection against infectious disease, of which she is now Principal Investigator (P01 HD 13021, 2003-08). She is currently Professor of Pediatrics at the University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center, where she founded and directs the Center for Epidemiology and Biostatistics that has 35 faculty and staff and a multi-disciplinary Human Milk Research Program that includes clinical and basic science investigators in eight divisions.

She has published extensively on breastfeeding promotion and human milk protection against infectious diseases. Her primary focus is on protection by human milk glycans and protection against infectious disease, but she has expanded her research to understanding the relationship between breastfeeding and chronic diseases. She has been an ad hoc reviewer for NIH on breastfeeding research and a technical advisor for international breastfeeding policy and programs for Gates Foundation, UNICEF, and WHO, is on the editorial board of the Journal of Human Lactation and the journal of the Academy of Breastfeeding Medicine. She is an elected member of the American Pediatric Society. She has over 100 publications, and is the primary author of the WHO monograph, Community-based Strategies for Breastfeeding Promotion and Support in Developing Countries (2004).

She has served as Chair of the Milk Club of the (American) Society for Pediatric Research for the past 4 years. In 1997, she received a Young Investigator award from ISRHML for her randomized trial of breastfeeding support (Lancet, 1999). She was co-organizer of the 2002 ISRHML international meeting in Mexico and is co-editor of the book Protecting Infants through Human Milk: Advancing the Scientific Evidence. She currently serves on the Executive Committee of ISRHML and is helping with the upcoming ISRHML conference in Niagara Falls.

Credentials

BA: Rice University, Houston, Texas Major: 1977 History/International Studies

MSc: University of the West Indies, Kingston, Jamaica. 1981 Nutrition

PhD: The University of Texas School of Public Health, Houston.TX 1991.

Awards and Honors

Jackie Schnell Memorial Scholar, Brown College, Rice University, 1974
Traineeship, Univ. Texas School of Public Health, 1979-1980
Society of Public Health Educators, Inc., the CINCH Project Program Excellence Award, 1996-
Young Investigator Presentation Award from the International Society for Research in Human Milk and Lactation, 1997
Dean's Achievement Award in Research, Eastern Virginia Medical School, Norfolk, Virginia, 1999
Fellow, Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program, MCP Hahnemann University, 2000-2001
Elected Member, American Pediatric Society, 2003

Research Grants and Contracts

Principal Investigator
National Institute of Child Health and Human Development
"The Role of Human Milk in Infant Nutrition and Health" (HD 13021) Program Project Grant
2001-2008

Co-Investigator
National Immunization Program, Centers for Disease Control and Prevention "National Vaccine Surveillance Network." Cooperative Agreement (M. Staat, PI)
2002-1007.

Co-Investigator
National Institute of Health-NIAID
"Characterization of Human Caliciviruses." (Jiang, PI)
2002-2007.

Co-Investigator
National Institute of Health - NIAID
"Molecular Epidemiology and Impact of Human Astroviruses." (Mitchell, PI) 2001-2006

Procter & Gamble, Inc. "Bang Bao" China Scholar Program. PI 2004-2007

Publications, Most Recent

Noguera-Obenza M, Ochoa TJ, Gómez HF, Guerrero ML, Herrera-Insua I, Morrow AL, Ruiz-Palacios G, Pickering LK, Guzmán CA, Cleary TG. Human milk secretory antibodies against attaching and effacing Escherichia coli antigens.Emerg Infect Dis. 2003;9(5):545-551.

Butterfoss FD, Morrow AL, Webster JD, Crews RC. The Coalition Training Institute: Training for the long haul.J Public Health Management and Practice. 2003; 9:522-9.

Huang PW, Farkas T, Marionneau S, Zhong WM, Ruvoën-Clouet N, Morrow AL, Altaye M, Pickering LK, Newburg D, LePendu J, Jiang X. Noroviruses bind to human ABO, Lewis and secretor histo-blood group antigens: Identification of four distinct strain-specific patterns.Journal of Infectious Diseases. 2003;188:19-31.

Gonzalez K, Meinzen-Derr JK, Burke B, Hibler A, Kravinsky B, Hess S, Pickering LK, Morrow AL. Evaluation of a Lactation Support Service in a Children's Hospital Neonatal Intensive Care Unit.J Hum Lact 2003; 19(3):286-92.

Newburg DS, Ruiz-Palacios GM, Altaye M, Chaturvedi P, Meinzen-Derr J, Guerrero M, Morrow AL. Innate protection conferred by fucosylated oligosaccharides of human milk against diarrhea in breastfed infants.Glycobiology 2004; 14(3): 253-63. Erratum: Glycobiology 2004;14:13G.

Wills-Karp M, Brandt D, Morrow AL. Understanding the origin of asthma and its relationship to breastfeeding.Adv Exp Med Biol 2004; 554: 171-191.

Rea MF, Morrow AL. Protecting, promoting, and supporting breastfeeding among women in the labor force.Adv Exp Med Biol 2004; 554:121-32.

Davidson B, Meinzen-Derr JK, Wagner CL, Newburg DS, Morrow AL. Fucosylated oligosaccharides in human milk in relation to gestational age and stage of lactation.Adv Exp Med Biol 2004; 554:427-430.

Meinzen-Derr JK, Guerrero ML, Altaye M, Ruiz-Palacios GM, Morrow AL. Duration of exclusive breastfeeding and risk of anemia in a cohort of Mexican infants.Adv Exp Med Biol 2004; 554:395-398.

Morrow AL, Ruiz-Palacios GM, Altaye M, Jiang X, Guerrero ML, Meinzen-Derr JK, Farkas T, Chaturvedi P, Pickering LK, Newburg DS. Human milk oligosaccharide blood group epitopes and innate immune protection against campylobacter and calicivirus diarrhea in breastfed infants.Adv Exp Biol Med 2004;554:443-446.

Jiang X, Huang P, Zhong W, Morrow AL, Ruiz-Palacios GM, Pickering LK. Human milk contains elements that block binding of noroviruses to histo-blood group antigens in saliva.Adv Exp Biol Med 2004; 554:447-450.

Newburg DS, Ruiz-Palacios GM, Altaye M, Chaturvedi P, Guerrero ML, Meinzen-Derr JK, Morrow AL. Human milk 1,2-linked fucosylated oligosaccharides decrease risk of diarrhea due to stable toxin of E. coli in breastfed infants.Adv Exp Med Biol 2004; 554:457-461.

Farkas T, Zhong WM, JingY, Huang PW, Moreno Espinosa S, Martinez M, Morrow AL, Ruiz-Palacios GM, Pickering LK, Jiang X. Genetic diversity among Sapoviruses.Arch Virol 2004;149: 1309-23. Epub 2004 Mar 17.

Morrow AL, Ruiz-Palacios GM, Altaye M, Jiang X, Guerrero ML, Meinzen-Derr JK, Farkas T, Chaturvedi P, Pickering LK, Newburg DS. Human milk oligosaccharides are associated with protection against diarrhea in breastfed infants.J Pediatr 2004;145:297-303

Morrow AL, Dawodu A. Influencing birth outcomes in Nepal.Lancet. 2004; 11:364:914-5.

Morrow AL, Rangel JM. Human milk protection against infectious diarrhea: Implications for prevention and clinical care.Semin Pediatr Infect Dis. 2004;15(4):221-8.

Jiang X, Huang P, Zhong W, Tan M, Farkas T, Morrow AL, Newburg DS, Ruiz-Palacios GM, Pickering LK. Human milk contains elements that block binding of noroviruses to human histo-blood group antigens in saliva.J Infect Dis. 2004 Nov 15;190(10):1850-9. Epub 2004 Oct 11.

Geraghty SR., Davidson BS, Sapsford AL, Ballard JL,.Warner BB, List BA, Morrow AL. The development of a research human milk bank.J Hum Lact 2005;21:59-66.

Huang P, Farkas T, Zhong W, Tan M, Thornton S, Morrow AL, Jiang X. Norovirus and Histo-Blood Group Antigens: Demonstration of a Wide Spectrum of Strain Specificities and Classification of Two Major Binding Groups among Multiple Binding Patterns.J Virol 2005; 79(11):6714-22.

Morrow AL, Ruiz-Palacios GM, Jiang X, Newburg DS. Human milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea.J Nutr 2005; 135(5):1304-7.

Newburg DS, Ruiz-Palacios GM, Morrow AL. Human milk oligosaccharides protect against enteric pathogens.Annu Rev Nutr 2005;25:37-58.

Professional Organization Memberships

Ambulatory Pediatric Association (APA)
American College of Epidemiology (ACE)
American Pediatric Society (APS)
American Public Health Association (APHA): Primary section - Maternal and Child Health
Global Health Council
International Society for Research on Human Milk and Lactation (ISRHML)
Society for Epidemiologic Research (SER)
Society for Executive Leadership in Academic Medicine (SELAM)
Society for Pediatric Epidemiologic Research (SPER)
The Milk Club (Pediatric Academic Societies)

Special Interests

Human milk, Child Health and Nutrition.

Presentations

Jiang X, Huang PW, Zhong WM, Morrow A, Ruiz-Palacios G, Pickering LK. Human milk contains elements that block binding of Noroviruses to histo-blood group antigens. Academic Societies' Annual Meeting, Washington State Convention & Trade Center, May 3-6, 2003.

Moreno-Espinosa S, Jiang X, Guerrero ML, Farkas, T, Ortega H, Meinzen-Derr J, Tuz F, Zhong WM, Monte JD, Reyes L, Pickering LK, Morrow AL, Ruiz-Palacios G. Natural history of human calicivirus infection in a cohort of Mexico. Pediatric Academic Societies' Annual Meeting, Washington State Convention & Trade Center, May 3-6, 2003.

Huang PW, Farkas T, Marionneau S, et al. Noroviruses bind to human ABO, Lewis and secretor histo-blood group antigens: Identification of four distinct strain-specific patterns. First International Meeting on Glycovirology, Viruses and Glycans, Goteborg, Sweden, June 15-19, 2003.

Moreno-Espinosa S, Farkas T, Guerrero ML, Jiang X, Morrow AL, Ruiz-Palacios GM. Natural History of Human Calicivirus Infection in a Cohort of Mexican Children. American Society for Virology Annual Meeting, University of California at Davis, July 12-16, 2003.

Morrow AL, Ruiz-Palacios GM, Altaye M, Guerrero ML, Meinzen-Derr J, Newburg DS. Human milk oligosaccharide protection against infant diarrhea. Pediatric Academic Societies' annual meeting, Seattle, Washington May 3-6, 2003.

Newburg DS, Morrow AL, Matson DO, Peterson JA, Altaye M, Ruiz-Palacios GM, Pickering LK. Concentrations of anti-rotavirus components of human milk over the course of lactation. Pediatric Academic Societies' annual meeting, Seattle, Washington May 3-6, 2003.

Newburg DS, Ruiz-Palacios GM, Altaye M, Chaturvedi P, Guerrero ML, Meinzen-Derr J, Morrow AL. 1,2-linked fucosyloligosaccharides comprise a major component of the innate immune system of human milk. Glycobiology 2003;13: 885 (#223).

Newburg DS, Altaye M, Morrow AL. Is the expression of human milk fucosylated oligosaccharide during the first month of lactation representative of the first year of lactation? Glycobiology 2003;13: 885 (#224).

Ammerman RT, Putnam FW, Stevens J, Holleb LJ, Hulsmann JE, Morrow AL, Geraghty SR, & Van Ginkel JB. Breastfeeding in first time mothers in early prevention. Poster presented at the annual convention of the American Psychological Association, Honolulu. July, 2004

Martin LJ, Banach W, Geraghty S, Dolan L, Morrow AL. Presence of Adiponectin and Leptin in Human Milk. (Poster-symposium presentation), Pediatric Academic Societies Meeting, San Francisco, May 2004.

Ammerman R, Morrow AL, et al. Breastfeeding in First Time Mothers in Home Visitation (Poster) Pediatric Academic Societies Meeting, San Francisco, May 2004.

Kerrey B, Braunwart J, Vieira J, Morrow AL, Schleiss M. A Cell Culture System for Examination of the Effect of Freezing on the Recovery of Cytomegalovirus From Human Breast Milk. (Poster-symposium presentation) Pediatric Academic Societies Meeting, San Francisco, May 2004.

Mitchell DK, Walter JE, Jiang X, Guerrero ML, Meinzen-Derr J, Primeggia J, Pickering LK, Altaye M, Ruiz-Palacios G, Morrow AL. Molecular Epidemiology of Human Astrovirus Infections Among Children in a Cohort Study in Mexico City. Pediatric Academic Societies Meeting, San Francisco, May 2004. Pediatric Academic Societies Meeting, San Francisco, May 2004.

Meinzen-Derr J, Morrow AL, Donovan E, et al. The Role of Human Milk Feedings in Risk of Late-Onset Sepsis. (Platform presentation). Pediatric Academic Societies Meeting, San Francisco, May 2004.

Walter JE, Afflerbach C, Jiang X, Matson DO, Pickering LK, Morrow AL, Guerrero ML, Ruiz-Palacios G, Mitchell DK. Characterization of a Novel Astrovirus from Mexican Children. Pediatric Academic Societies Meeting, San Francisco, May 2004.

Martin LJ, Banach W, Geraghty S, Dolan L, Morrow AL. Detection of Adiponectin in Human Milk: Implications for Early Metabolic Regulation. International Society for Research in Human Milk and Lactation. Cambridge, England, September 2004.

Meinzen-Derr J, Morrow AL, Donovan E, et al. The Role of Human Milk Feedings in Risk of Late-Onset Sepsis. International Society for Research in Human Milk and Lactation. Cambridge, England, September 2004.

Geraghty SR, Davidson BS, Sapsford AL, Ballard JL, Warner BB, List BA, Morrow AL. The development of a research human milk bank. Academy of Breastfeeding Medicine Annual Meeting. October 2004.

Farkas T, Deng X, Ruiz-Palacios G, Morrow AL, Jiang X. Expression of a GII recombinant Sapovirus capsid protein in E. coli and the development of an antibody detection enzyme immune assay. American Society of Virology 2005 conference

Olsen IE, Meinzen-Derr J, Lawson ML, Morrow AL. Unexpectedly high SGA rates by gestational Age in a NICU Cohort. Pediatric Academic Societies 2005 conference

Morrow AL , Guerrero ML, Meinzen-Derr J, Gallegos, HO, Altaye M, Ruiz-Palacios G. Exclusive Breastfeeding in the First 6 Months in Relations to Diarrhea in a Cohort of Mexican Children 0-24 Months of Age. Pediatric Academic Societies 2005 conference