Find a Health Care Professional / Researcher

John P. Pestian, PhD, MBA

Title

Director, Computational Medicine Center

Appointment

Associate Professor of Pediatrics

Email

john.pestian@cchmc.org

Phone

513-636-1627

Fax

513-636-2056

Bio

The founding director of the Division of Biomedical Informatics, Dr. Pestian now focuses on directing and developing the Computational Medicine Center (CMC). The CMC was established in 2003 by a $28 million grant from Ohio's Third Frontier Project.

Dr. Pestian's research lab is focused on using the science of natural language understanding in biomedical settings. Along with a growing list of collaborators, lab members focus on developing and implementing neuro-cognitive algorithms that enable computers to understand the concepts and semantic relationships within clinical text

Credentials

BS: Psychology, St. Francis College, Lorreto, PA, 1981.

MA: Business Administration, University of Steubenville, Steubenville, OH, 1987.

PhD: Health Services and Organizational Research, Virginia Commonwealth University, Richmond, VA, 1994.

Awards and Honors

Editor-in-Chief, Medical Informatics Insight, August 2007 - Present
Board Member, Hatton Research Foundation, TriHealth, Cincinnati, OH
Chair, Regional Medical Natural Language Processing Research Group (University of Cincinnati, Cincinnati Children's, Ohio State Linguistics, Ohio State Biomedical Informatics)
Chair, International Challenge for Medical Text Classification, IEEE Symposium on Computational Intelligence and Data Mining, CIDM 2007
Chair, Biomedical Informatics Session, IEEE Symposium on Computational Intelligence and Data Mining, CIDM 2007
Committee, BioNLP Session, Association of Computational Linguistics, 2007
Chair, Pediatric Natural Language Understanding Research Group, 2005

Research Grants and Contracts

Title: Computational Medicine Center
Sponsor: Ohio BRTT Partnership Award
Project funding: $8.5 million/year
Dates: 07/01/2004 - 06/30/2007
Role: Director and Co-investigator

Title: General Clinical Research Center
Sponsor: National Institutes of Health
Project funding: $100,000/year
Dates: 12/30/1993 - 11/30/2006
Role: Informatics core director

Title: Cincinnati Rheumatic Diseases Center
Sponsor: National Institutes of Health
Project funding: $100,000/year
Dates: 03/01/2001 - 02/28/2011
Role: Informatics core director

Title: Gene Expression in Pediatric Arthritis
Sponsor: National Institutes of Health
Dates: 08/22/2003 - 07/31/2003
Role: Co-investigator

Title: Vaccine Trail Unit
Sponsor: National Institutes of Health
Dates: 2003-2008
Project funding: $4.5 million
Role: Informatics core director

Title: Genome Research Institute
Sponsor: Ohio Board of Regents
Project funding: $4.5 million total, $700,000 for informatics
Dates: 2003-2005
Role: Co-investigator

Title: Development of a High Performance Computing Environment for Pediatric Research
Sponsor: Ohio Board of Regents, Sun Microsystems
Dates: 06/2001 - 06/2002
Project funding: $2.3 million
Role: Prinicipal investigator

Title: Healthy Start Initiative, Evaluation Component
Sponsor: U.S. Department of Health and Human Service
Project funding: $91,000/year
Dates: 1999-2003
Role: Co-investigator

Title: Healthy Start Phase II Demonstration Grant, Coalition Development, Resource Mothers, and Fetal Infant Mortality Review Components
Sponsor: U.S. Department of Health and Human Service
Project funding: $700,000/year
Dates: 1997-2003
Role: Co-investigator

Title: Development of Newborn Hearing Screening Computerized Tracking System for Virginia's Hospitals
Sponsor: Virginia Department of Health
Project Funding: $125,000
Dates: 01/2000 - 06/2000
Role: Prinicipal investigator

Title: Enhancement of the School Health Information System
Sponsor: Children's Health System and Eastern Virginia Medical School
Project Funding: $920,000
Dates: 1998-2000
Role: Principal investigator

Title: Development of Internet Based Reporting System for Measuring Pediatric Quality of Care in Virginia
Sponsor: Virginia Joint Legislative Commission on Health Care
Project Funding: $75,000
Dates: 01/1999 - 12/1999
Role: Co-investigator

Publications, Most Recent

Duch W, Matykiewicz P, Pestian J. Neurolinguistic approach to natural language processing with applications to medical text analysis. Neural Netw. 2008 Jun 7.

Pestian JP, Matykiewicz P. Classification of suicide notes using natural language processing. Proceedings of ACL BioNLP; 2008 June: Columbus. p. 96-7.

Duch W, Matykiewicz P, Pestian JP. Neurolinguistic approach to vector representation of medical concepts. Advances in neural networks research; 2008 Jun 7. p. 3110-15.

Rajan J, Davis KC, Matykiewicz P, Duch W, Pestian JP. Medical acronym disambiguation using online sources. Enterprise Information Systems and Web Technologies 2007:123-30.

Duch W, Matykiewicz P, Pestian J. Neurolinguistic approach to vector representation of medical concepts. IJCNN; 2007. p. 3110-15.

Duch W, Matykiewicz P, Pestian J. Neurolinguistic approach to vector representation of medical concepts. Proc. of the 20th Int. Joint Conference on Neural Networks (IJCNN); 2007 Aug 12-17; Orlando: IEEE Press. p. 1808.

Duch W, Matykiewicz P, Pestian J. Towards understanding of natural language: neurocognitive inspirations. In: J. Marques de Sá et al., editors: Artificial neural networks - ICANN 2007, Proceedings, Part II: Springer-Verlag LNCS 4669. p. 953–62.

Pestian JP, Brew C, Matykiewicz PM, Hovermale DJ, Johnson N, Cohen KB, Duch W. A shared task involving multi-label classification of clinical free text. Proceedings of ACL BioNLP; 2007 Jun; Prague.

Matykiewicz P, Duch W, Pestian JP. Non ambiguous concept mapping in medical domain. ICAISC; 2006.

Matykiewicz P, Pestian J, Duch W. Unambiguous concept mapping in radiology reports: graphs of consistent concepts. AMIA Annu Symp Proc; 2006 Nov; Washington, DC. p. 1024.

Pestian JP, Itert L, Anderson C, Duch W. Preparing clinical text for use in biomedical research. J Database Manage. 2006 Apr-Jun;17(2):1-11.

Wade SL, Wolfe C, Brown TM, Pestian JP. Putting the pieces together: preliminary efficacy of a web-based family intervention for children with traumatic brain injury. J Pediatr Psychol. 2005 Jul-Aug;30(5):437-42.

Itert L, Duch W, Pestian J. Analysis of medical discharge summaries based on prior knowledge. Proceedings of the International Conference on Artificial Neural Networks; 2005; Warsaw, Poland.

Pestian JP, Itert L, Duch W. Development of a pediatric text-corpus for part-of-speech tagging. In: Wierzchon ST, Trojanowski K, editors. Intelligent information processing and web mining: Proceedings of the International IIS: IIPWM'04; 2004 May 17-20; Zakopane, Poland: Berlin: Springer; 2004. p. 219-26.

Wade SL, Wolfe CR, Pestian JP. A web-based family problem-solving intervention for families of children with traumatic brain injury. Behav Res Methods Instrum Comput. 2004 May;36(2):261-9.

Pestian JP, Aronow BJ, Davis KC. Schema design and data collection in the Discovery System. In: Valafar F, editor. Proceedings of the 2002 International Conference on Mathematics and Engineering Techniques in Medicine and Biological Sciences (METMBS'02); 2002; Las Vegas; 2002.