Rosa Serra, Ph.D.
Title
Assistant Professor
Email
serrar@ucmail.uc.edu
Phone
513-558-4626
Fax
513-558-5738
Credentials
Ph.D.:The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, 1992
Post-Doctoral training: Department of Cell Biology, Vanderbilt University School of Medicine, Nashville, TN, 1992- 1995.
Research
skeletal develoment, cancer
Visit Dr. Serra's Web site within UC's Department of Molecular and Cellular Biology.
Publications, Most Recent
Joseph H, Gorska AE, Sohn P, Moses HL, Serra R: Transgenic mice that express a truncated kinase defective TGF-beta type II receptor in the mammary gland stroma demonstrate increased lateral duct branching.Molecular Biology of the Cell 10:1221-1234, 1999.
Serra R, Karapalis A, Sohn P: PTHrP-dependent and -independent effects of TGF-beta 1 on endochondral bone formation.Journal of Cell Biology 145:783-794, 1999.
McDonnell M, Law B, Serra R, Moses HL: Antagonistic Effects of TGF-beta1 and BMP-6 on Skin Keratinocyte Differentiation.Exp Cell Res. 263(2):265-273, 2001.
Alvarez J, Horton J, Sohn P, Serra R: The perichondrium plays an important role in mediating the effects of TGF-beta 1 on endochondral bone formation.Developmental Dynamics 221:311-321, 2001.
Bragg A, Moses HL, Serra R: Signaling to the Epithelium is Not Sufficient to Mediate all of the Effects of TGF-beta1 and Bmp4 on Murine Embryonic Lung Branching Morphogenesis.Mechanisms of Development 109:13-26, 2001.
Special Interests
The overall goal of the laboratory is to understand the role and mechanism of TGF-beta signaling in embryonic and post-natal development and to apply this knowledge to the understanding and treatment of human degenerative and neoplastic disease.
Grants"TGF-Beta SIGNALING IN CHONDROCYTE DIFFERENTIATION" Serra, PI
Agency: NIH/NIAMS
Type: R01 AR45605
Period: 9/30/98 through 8/31/02
"MECHANISM OF CHONDROPROTECTION BY TGF-Beta" Serra, PI
Agency: NIH/NIAMS
Type: R01 AR46982
Period: 5/1/00 through 4/30/05
"TGF-Beta IN STROMAL-EPITHELIAL INTERACTIONS IN MAMMARY GLAND" Serra, PI
Agency: NIH/NCI
Type: R01 CA91974
Period: 7/1/2001 to 6/30/2006
Presentations
1999, Bones and Teeth Gordon Conference
1999, Biology Department Seminar Series, Centre College, Kentucky.
1999, Biology Department Seminar Series, Indiana University Purdue University at Indianapolis.
2001, Department of Biomedical Engineering, The Cleveland Clinic Foundation
2001, Fourth Annual Meeting of The Parathyroid Hormone related Proteins: Clinical and Basic Aspects.
Funded Training Programs
"THE INFLUENCE OF STROMAL TGF-beta RECEPTOR SIGNALING ON MOUSE MAMMARY NEOPLASIA"
P.I. Michael Crowley Serra, Mentor
Agency: The Department of the Army Office of Congressionally Directed Research.
Type: Post-doctoral Fellowship
Period: 8/1/01 to 7/31/04
Memberships
American Association for the Advancement of Science, member, 1988
Society for Developmental Biology, member, 1996
American Society for Cell Biology, member, 1996
American Society for Bone and Mineral Research, 2000
