Find a Health Care Professional / Researcher

Bo Wang, DVM, PhD

Appointment

Assistant Professor of Pediatrics

Email

bo.wang@cchmc.org

Phone

513-636-5305

Fax

513-636-5314

Credentials

1982: D.V.M, Veterinary medicine, Shandong Agricultural University; Taian, China
1989: DEA (M.S), Animal Physiology, Ecole Nationale Veterinaire de Nantes; Nantes, France
1997: Ph.D., Immunology, Universite Louis Pasteur, Strasbourg, France

Position History

1982-1989 Lecturer, Department of Veterinary Medicine, Shandong Agricultural University, China

Researcher Scientist, School of Veterinary Medicine of Nantes, France (Ecole Nationale Veterinarie de Nantes)

1997-2001 Postdoctoral Research Associate (w/ Dr. Jeffrey A. Frelinger), Department of Microbiology and Immunology, University of North Carolina at Chapel Hill

2001-present Assistant Professor of Pediatrics, Children's Hospital Research Foundation/University of Cincinnati, Ohio

Awards and Honors

Honored as best faculty member, Shandong Agricultural University

Research Fellowship from Ministry of Agriculture of France

Honored as among 10% best PhD thesis in France.

PhD Fellowship from Universite Louis Pasteur de Strasbourg, France

Publications, Most Recent

Plassiart G, Guelfi JF, Ganiere JP, Wang B, André-Fontaine G, Wyers M. Hematological parameters and visceral lesions relationship in rabbit viral hemorrhagic disease. J Vet Med 1992, B 39:443-453.

Ganiere JP, André-Fontaine G, Drouin P, Faye B, Rosner G, Fourichon C, Wang B, Tillon JP. L'écopathologie: une méthode d'approche de la santé en élevage. INRA Productions Animales 1991, 4 (3):247-256.

Katz JD, Wang B, Haskin K, Benoist C, Mathis D. Following a diabetogenic T cell from genesis to pathogenesis. Cell 1993, 74:1089-1100.

Katz JD, Wang B, Benoist C, Mathis, D. Transgenic mice carrying the rearranged T cell receptor of a diabetogenic T cell clone. In: Autoimmunity: Experimental aspects. M. Zouali, Ed. Springer-Verlag, Berlin 1994, pp 12-28.

Katz JD, Wang B, Adré I, Gonzalez A, Benoist C, Mathis D. Following diabetogenic T cells in transgenic mice. In: New Research Trends in Immunological Disease by N. Minato et al, Academic Press (1996). By the Ryoichi Naito Foundation for Medical Research, 1996, pp: 69-76.

Wang B, Gonzalez A, Benoist C, Mathis D. The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus. Eur J Immunol 1996, 26:1762-1769.

André I., Gonzalez A, Wang B, Katz J, Benoist C, Mathis D. Checkpoints in the progression of autoimmune disease: Lessons from diabetes models. Proc Natl Acad Sci USA 1996, 93:2260-2263.

Wang B, Benoist C, Mathis D. The immunosuppressant 1,5-deoxspergualin reveals commonality between pre-T and pre-B cell differentiation. J Exp Med 1996, 183:1-10.

Wang B, Benoist C, Mathis D. Interferon- impacts at multiple points during the progression of autoimmune diabetes. (Non-obese diabetic mice/interferon- receptor knock-out mice).Proc Natl Acad Sci USA 1997, 94:13844-13849.

Wang B, Benoist C, Mathis D. IL-4 deficiency does not worsen disease in NOD mice. Diabetes 1998, 47:1207-1211.

Tisch R, Wang B, Serreze D. Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope-dependent. J Immunol 1999, 163: 1178-1187.

Wang B, R Maile, R Greenwood, E Collins, Frelinger J. Naïve CD8+ T cells do not require co-stimulation for proliferation and differentiation into cytotoxic effector cells. J Immunol 2000, 164: 1216-1222.

Tisch R, Wang B, Weaver DJ, Liu B, Bui T, Arthos J, Serreze D. Antigen-specific mediated suppression of β cell autoimmunity by plasmid DNA vaccination. J Immunol 2001 166: 2122-2132.

Wang B, Norbury C, Greenwood R, Bennink J, Yewdell J, Frelinger J. Multiple paths for activation of naïve CD8+ T cells: CD4-independent help.J Immunol 2001, 167: 1283-1289.

Tisch R, Wang B, Atkinson MA, Serreze D, Friendline R. A glutamic acid decarboxylase 65-specific Th2 cell clone immunoregulate autoimmune diabetes in nonbese diabetic mice. J Immunol 2001, 166: 6925-6936.

Maile R, Wang B, Schooler W, Meyer A, Collins E, Frelinger JA. Antigen-specific modulation of an immune response by in vivo administration of soluble MHC Class I tetramers.J Immunol 2001, 167: 3708-3714.

Wang.B, Sharma. A, Maile. R, Saad. M, Collins. E, and Frelinger J. Peptide termini play a significant role in TCR recognition. J. Immunol 2002, 169: 3137-3145.

Greenwood R, Wang B, Midkiff K, White II GC, Lin H, Stafford D, Frelinger JA. Identification of T cell epitopes in clotting factor IX. J. Thrombosis and Haemostasis, 2003, 1: 95-102.