Punam Malik, MD
- Director, Cincinnati Comprehensive Sickle Cell Center
- Program Leader, Hematology and Gene Therapy Program
- Marjory J. Johnson Chair, Gene and Cell Therapy
- Professor, UC Department of Pediatrics
- punam.malik@cchmc.org
- Board Certified
About
MBBS: University of Delhi, New Delhi, India, 1985.
MD: University of Delhi, New Delhi, India, 1989.
MS: University of Maryland, Baltimore, MD, 1991.
Fellowship: Children's Hospital Los Angeles, University of Southern California, 1995.
Services and Specialties
Cancer and Blood Diseases, Sickle Cell and Hemoglobin Disorders
Research Areas
Experimental Hematology and Cancer Biology, Cancer and Blood Diseases, Hematology
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
Generation of a tyrosine hydroxylase-2A-Cre knockin non-human primate model by homology-directed-repair-biased CRISPR genome editing. Cell Reports: Methods. 2023; 3:100590.
Strategies for precise gene edits in mammalian cells. Molecular Therapy-Nucleic Acids. 2023; 32:536-552.
CRISPR/Cas9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease. Journal of immunology (Baltimore, Md. : 1950). 2023; 210:173.21.
Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI). Gene Therapy (Basingstoke). 2023; 30:216-221.
Future Directions and Resource Needs for National Heart, Lung, and Blood Institute (NHLBI) Gene Therapy Research: A Report of an NHLBI Workshop. Human Gene Therapy. 2023; 34:83-89.
Preclinical Evaluation of Foamy Virus Vector-Mediated Gene Addition in Human Hematopoietic Stem/Progenitor Cells for Correction of Leukocyte Adhesion Deficiency Type 1. Human Gene Therapy. 2022; 33:1293-1304.
CRISPR/CAS9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease. Blood. 2022; 140:10200-10201.
NRASQ61R mutation in human endothelial cells causes vascular malformations. Angiogenesis. 2022; 25:331-342.
Differential CXCR4 expression on hematopoietic progenitor cells versus stem cells directs homing and engraftment. JCI insight. 2022; 7:e151847.
Successful use of veno-venous extracorporeal membrane oxygenation for acute chest syndrome in a child with sickle cell disease and SARS-CoV-2. Pediatric Pulmonology. 2022; 57:1096-1099.
From the Blog
Preventing Adult Sickle Cell Deaths From Kidney Disease May Start With Improved Childhood Testing
Punam Malik, MD, Omar Niss, MD4/15/2020
Gene Therapy Advances Raise Hopes for Curing Sickle Cell Disease
Punam Malik, MD6/27/2019
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