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Center for Autoimmune Genomics and Etiology
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Center for Autoimmune Genomics and Etiology
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Selected Publications
Top 25 Publications from FY17 Based on Impact Factor
Fang J; Bolanos LC; Choi K; Liu X; Christie S; Akunuru S; Kumar R; Wang D; Chen X; Greis KD.
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature Immunology
. 2017; 18:236-245.
Almoguera B; Vazquez L; Mentch F; Connolly J; Pacheco JA; Sundaresan AS; Peissig PL; Linneman JG; McCarty CA; Crosslin D.
Identification of Four Novel Loci in Asthma in European American and African American Populations.
American journal of respiratory and critical care medicine
. 2017; 195:456-463.
Litosh VA; Rochman M; Rymer JK; Porollo A; Kottyan LC; Rothenberg ME.
Calpain-14 and its association with eosinophilic esophagitis.
Journal of Allergy and Clinical Immunology
. 2017; 139:1762-1771.e7.
Ombrello MJ; Arthur VL; Remmers EF; Hinks A; Tachmazidou I; Grom AA; Foell D; Martini A; Gattorno M; Özen S.
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.
Annals of the rheumatic diseases
. 2017; 76:906-913.
Hinks A; Bowes J; Cobb J; Ainsworth HC; Marion MC; Comeau ME; Sudman M; Han B; Juvenile Arthritis Consortium for Immunochip; Becker ML.
Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.
Annals of the rheumatic diseases
. 2017; 76:765-772.
Young KA; Munroe ME; Guthridge JM; Kamen DL; Niewold TB; Gilkeson GS; Weisman MH; Ishimori ML; Kelly J; Gaffney PM.
Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
Annals of the rheumatic diseases
. 2017; 76:153-158.
Deng Y; Zhao J; Sakurai D; Sestak AL; Osadchiy V; Langefeld CD; Kaufman KM; Kelly JA; James JA; Petri MA.
Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Annals of the rheumatic diseases
. 2016; 75:2007-2013.
Munroe ME; Lu R; Zhao YD; Fife DA; Robertson JM; Guthridge JM; Niewold TB; Tsokos GC; Keith MP; Harley JB.
Altered type II interferon precedes autoantibody accrual and elevated type i interferon activity prior to systemic lupus erythematosus classification.
Annals of the rheumatic diseases
. 2016; 75:2014-2021.
Guo H; Cranert SA; Lu Y; Zhong MC; Zhang S; Chen J; Li R; Mahl SE; Wu N; Davidson D.
Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1.
The Journal of Experimental Medicine
. 2016; 213:2187-2207.
Mao AP; Constantinides MG; Mathew R; Zuo Z; Chen X; Weirauch MT; Bendelac A.
Multiple layers of transcriptional regulation by PLZF in NKT-cell development.
Proceedings of the National Academy of Sciences of the United States of America
. 2016; 113:7602-7607.
Cox JW; Ballweg RA; Taft DH; Velayutham P; Haslam DB; Porollo A.
A fast and robust protocol for metataxonomic analysis using RNAseq data.
Microbiome
. 2017; 5:7.
Vander Lugt B; Riddell J; Khan AA; Hackney JA; Lesch J; DeVoss J; Weirauch MT; Singh H; Mellman I.
Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation.
The Journal of Cell Biology
. 2017; 216:779-792.
Imai F; Chen X; Weirauch MT; Yoshida Y.
Requirement for Dicer in Maintenance of Monosynaptic Sensory-Motor Circuits in the Spinal Cord.
Cell Reports
. 2016; 17:2163-2172.
Vignesh KS; Figueroa JAL; Porollo A; Divanovic S; Caruso JA; Jr DGS.
IL-4 Induces Metallothionein 3-and SLC30A4-Dependent Increase in Intracellular Zn2+ that Promotes Pathogen Persistence in Macrophages.
Cell Reports
. 2016; 16:3232-3246.
Lu R; Munroe ME; Guthridge JM; Bean KM; Fife DA; Chen H; Slight-Webb SR; Keith MP; Harley JB; James JA.
Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies.
Journal of Autoimmunity
. 2016; 74:182-193.
Li H; Reksten TR; Ice JA; Kelly JA; Adrianto I; Rasmussen A; Wang S; He B; Grundahl KM; Glenn SB.
Identification of a Sjogren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.
PLoS genetics
. 2017; 13:e1006820.
Verma SS; Cooke Bailey JN; Lucas A; Bradford Y; Linneman JG; Hauser MA; Pasquale LR; Peissig PL; Brilliant MH; McCarty CA.
Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium.
PLoS genetics
. 2016; 12:e1006186.
Bush WS; Crosslin DR; Owusu-Obeng A; Wallace J; Almoguera B; Basford MA; Bielinski SJ; Carrell DS; Connolly JJ; Crawford D.
Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network..
Clinical Pharmacology and Therapeutics
. 2016; 100:160-169.
Cushion MT; Collins MS; Sesterhenn T; Porollo A; Vadukoot AK; Merino EJ.
Functional Characterization of Pneumocystis carinii Inositol Transporter 1.
mBio
. 2016; 7:e01851-16.
Kottyan LC; Rothenberg ME.
Genetics of eosinophilic esophagitis.
Mucosal immunology
. 2017; 10:580-588.
Merkel PA; Xie G; Monach PA; Ji X; Ciavatta DJ; Byun J; Pinder BD; Zhao A; Zhang J; Tadesse Y.
Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.
Arthritis and Rheumatology
. 2017; 69:1054-1066.
Munroe ME; Young KA; Kamen DL; Guthridge JM; Niewold TB; Costenbader KH; Weisman MH; Ishimori ML; Wallace DJ; Gilkeson GS.
Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.
Arthritis and Rheumatology
. 2017; 69:630-642.
Han X; Wang Y; Zhang X; Qin Y; Qu B; Wu L; Ma J; Zhou Z; Qian J; Dai M.
MicroRNA-130b Ameliorates Murine Lupus Nephritis Through Targeting the Type I Interferon Pathway on Renal Mesangial Cells.
Arthritis and Rheumatology
. 2016; 68:2232-2243.
Schulert GS; Fall N; Harley JB; Shen N; Lovell DJ; Thornton S; Grom AA.
Monocyte MicroRNA Expression in Active Systemic Juvenile Idiopathic Arthritis Implicates MicroRNA-125a-5p in Polarized Monocyte Phenotypes.
Arthritis and Rheumatology
. 2016; 68:2300-2313.
Dauber A; Cunha-Silva M; Macedo DB; Brito VN; Abreu AP; Roberts SA; Montenegro LR; Andrew M; Kirby A; Weirauch MT.
Paternally Inherited DLK1 Deletion Associated With Familial Central Precocious Puberty.
Journal of Clinical Endocrinology and Metabolism
. 2017; 102:1557-1567.