Annual Grant Award Dollars

Investigator Title Sponsor ID Dates Amount
Nancy Ratner, PhD Ras Proteins in Nerve Tumorigensis National Institutes of Health R37 NS083580 04/01/2014 - 03/31/2019 $390,000
FuKun Guo, PhD Novel Signaling Function of Cdc42 GTPase In Vivo National Institutes of Health R01 GM108661 05/01/2014 - 02/28/2018 $273,000
Qing Richard Lu, PhD The Establishment of Schwann Cell Polarity and the Inflation of Myelination National Institutes of Health (The Univ of California, San Francisco) R01 NS062796 05/01/2014 - 04/30/2019 $122,850
Nancy Ratner, PhD Disordered Regulation of Wnt/beta-catenin Signaling in MPNST Development and Maintenance National Institutes of Health (University of Minnesota) R01 NS086219 08/15/2014 - 06/30/2019 $274,835
Yi Zheng, PhD Targeting Cdc42 for Bone Marrow Transplant Therapies National Institutes of Health R01 CA193350 05/01/2015 - 04/30/2020 $356,850
Nancy Ratner, PhD Brain Dysfunction in Neurofibromatosis National Institutes of Health R01 NS091037 04/01/2015 - 03/31/2020 $309,792
Kakajan Komurov, PhD Exploiting Proteotoxic Stress in Therapy-refractory HER2+ Breast Cancers National Institutes of Health R01 CA193549 05/01/2015 - 04/30/2020 $356,850
Elisa Boscolo, PhD Venous Malformations (VM): A Murine Model to Identify Therapies to Targer Aberrant Venous Development National Institutes of Health R01 HL117952 08/07/2014 - 04/30/2018 $351,000
Ronald R Waclaw, PhD Signaling Pathways Regulating Oligodendrocyte Development and Function National Institutes of Health R01 NS088529 04/01/2015 - 02/29/2020 $341,250
Qing Richard Lu, PhD Molecular Mechanisms of Oligodendrocyte Differentiation and Myelination National Institutes of Health R01 NS072427 09/20/2015 - 08/31/2020 $466,702
Damien Reynaud, PhD Investigating the Mechanisms of Leukemia Initiation in the Context of Obesity Department of Defense Army W81XWH1510344 09/01/2015 - 08/31/2018 $187,200
Daniel T. Starczynowski, PhD Investigating Genetic and Molecular Determinants of Myelodysplastic Syndromes The Leukemia and Lymphoma Society 133416 07/01/2015 - 06/30/2020 $110,000
Carolyn Lutzko, PhD CS1 Chimeric Antigen Receptor-Based Immunotherapy for Multiple Myeloma American Cancer Society National (Ohio State University Comprehensive Canc) RSG1424301LIB 01/01/2015 - 12/31/2018 $30,000
Marie-Dominique Filippi, PhD Hypoxia and Potassium Channel Activity in T Lymphocytes National Institutes of Health (University of Cincinnati) R01 CA095286 07/01/2015 - 06/30/2018 $9,185
Matthew Flick, PhD Novel Anti-fibrotic Mechanisms in Chemical-induced Liver Injury National Institutes of Health (Michigan State University) R01 ES017537 08/01/2015 - 06/30/2020 $35,407
Marie-Dominique Filippi, PhD Molecular Regulation of Neutrophil Transcellular Migration National Institutes of Health R01 GM112792 07/01/2015 - 06/30/2019 $308,100
Jose Cancelas-Perez
Carolyn Lutzko, PhD
G-CSF in Human Severe Congenital Neutropenia National Institutes of Health R01 GM110628 07/01/2015 - 06/30/2019 $308,100
Marie-Dominique Filippi, PhD
Punam Malik, MD
Regulation of Hematopoietic Stem Cell Self-renewal by GTPase Activating Protein Signaling National Institutes of Health R01 DK102890 07/01/2015 - 06/30/2020 $420,349
Yi Zheng, PhD Cdc42, Hematopoietic Stem Cell Polarity and Cell Fate National Institutes of Health R01 DK104814 12/15/2015 - 11/30/2019 $496,716
Navneet Kumar Singh, PhD Modelling and Targeting of Oncogenic Liability in Drug-Resistant Breast Cancer Department of Defense Army W81XWH1610028 03/01/2016 - 02/28/2019 $191,081
Hartmut Geiger, PhD Novel t-MDS Predisposing Genes and Pathways Edward P. Evans Foundation BSR2015 09/01/2015 - 08/31/2017 $200,000
Mei Xin, PhD Hippo Signaling in Heart Development and Repair National Institutes of Health R01 HL132211 04/01/2016 - 03/31/2021 $390,000
Yi Zheng, PhD
Hartmut Geiger
Blood Stem Cell Aging and Biomarker Studies National Institutes of Health R01 HL134617 08/01/2016 - 05/31/2020 $780,000
Jonathan Fletcher Cytokine Signaling in Neurofibroma Development National Institutes of Health F30 NS096796 03/01/2016 - 02/28/2018 $40,176
Molly Smith Aberrant Ubiquitin Editing in the Pathogenesis of Myeloid Malignancies National Institutes of Health F31 HL132420 09/01/2016 - 08/31/2020 $36,557
Mark Althoff Scribble in Hematopoietic Stem Cell Activity National Institutes of Health F31 HL132468 04/01/2016 - 03/31/2019 $36,036
Jianqiang Wu, MD miR-155 and RUNX Function in Neurofibroma Tumorigenesis and Therapy National Institutes of Health R01 NS097233 07/01/2016 - 06/30/2021 $341,250
James Mulloy, PhD The Role of Hedgehog Signaling in Gastric Tissue Repair and Regeneration National Institutes of Health (University of Cincinnati) R01 DK083402 07/01/2016 - 04/30/2021 $43,235
Jose Cancelas-Perez Multiscale Modeling of Myelodysplastic Syndromes National Institutes of Health (Virginia Commonwealth University) R01 HL128173 08/03/2016 - 03/31/2020 $103,256
Nancy Ratner, PhD Targeting Tumors with NF1 Loss National Institutes of Health (Trustees of Dartmouth) R01 NS095411 09/30/2015 - 07/31/2020 $222,286
Qing Richard Lu, PhD Chd7 Chromatin Remodeller Function in Myelination and Remyelination National Multiple Sclerosis Society (Inserm Délégation Régionale Paris 6) RG150102851 10/01/2015 - 09/30/2018 $90,360
Yi Zheng, PhD Targeting TET1 Signaling to Treat Acute Myeloid Leukemia National Institutes of Health (University of Cincinnati) R01 CA211614 01/01/2017 - 12/31/2021 $68,640
Lilith Reeves Disseminating Curative Biological Therapies for Rare Pediatric Diseases Natl. Ctr for Advancing Translational Sc (Children's Hospital Boston) U01 TR001814 09/01/2016 - 08/31/2021 $132,350
Mark Wunderlich Therapeutic Insights through Patient Derived Leukemia Xenografts National Institutes of Health R50 CA211404 09/15/2016 - 08/31/2021 $172,232
Nancy Ratner, PhD An Innovative NF1 Drug Discovery Pipeline for Preclinical Development of Novel Drugs Quickly, Safely, and Effectively The Children's Tumor Foundation (The Children's Tumor Foundation) CTF 10/15/2015 - 06/30/2018 $75,891
Daniel T. Starczynowski, PhD Rational Design of Dual IRAK1/4 Inhibitors as a New Therapy for MDS The Leukemia and Lymphoma Society 651117 10/01/2016 - 09/30/2019 $200,000
Damien Reynaud, PhD Hematopoietic Stem Cells in Obesity National Institutes of Health R56 HL131861 09/01/2016 - 08/31/2017 $390,000
Marie-Dominique Filippi, PhD Identifying Novel Therapeutic Targets for Pediatrics Leukemia Cancer Free Kids Filippi, Marie, CFK 07/01/2016 - 06/30/2017 $50,000
Robert A Coover, PhD Overcoming Signaling Deficiencies in MPNST Cancer Free Kids Cover, Robert, CFK 07/01/2016 - 06/30/2018 $42,500
Laura Barreyro, PhD Inhibition of UBE2N as a Therapeutic Approach in Pediatric Acute Myeloid Leukemia Cancer Free Kids Barreyro, Laura, CFK 07/01/2016 - 06/30/2018 $50,000
Chris Richard Evelyn, PhD RasGRP1 Inhibitor as a Novel Treatment Strategy for Childhood T-Cell Acute Lymphoblastic Leukemia (T-ALL) Cancer Free Kids Evelyn, Chris, CFK 07/01/2016 - 06/30/2018 $30,000
Daniel T. Starczynowski, PhD Decoding Innate Immune Signaling in Normal and Myelodysplastic Hematopoiesis National Institutes of Health R35 HL135787 01/10/2017 - 12/31/2023 $788,750
Qing Richard Lu, PhD Molecular and Signaling Mechanisms of Peripheral Nerve Sheath Tumorigenesis National Institutes of Health R37 NS096359 09/30/2016 - 08/31/2020 $529,965
Laura Barreyro, PhD Environmental Carcinogenesis and Mutagenesis Training Grant National Institutes of Health (University of Cincinnati) T32 ES007250 09/30/2015 - 09/29/2018 $38,340
Marie-Dominique Filippi, PhD Role of Viral Chemokine Receptors in Cytomegalovirus Latency National Institutes of Health (Louisiana State University) R01 AI087683 11/11/2016 - 06/30/2017 $3,048
Cindy LF Hochstetler Impact of Abnormal Bone Marrow Endothelial Niche on Hematopoiesis National Institutes of Health F31 HL136229 03/01/2017 - 02/29/2020 $37,176
Qing Richard Lu, PhD Functional Analysis of CHARGE Syndrome-related Chromatin Remodelers in CNS Myelination CHARGE Syndrome Foundation Lu, Qing, CHARGE 07/01/2016 - 06/30/2017 $50,000
Punam Malik, MD Cincinnati Center of Excellence in Hemoglobinopathies Research National Institutes of Health U01 HL117709 06/01/2016 - 05/31/2018 $1,784,042
Tomoya Muto, PhD Cooperative Effect of Innate Immune Pathway Activation and Concurrent Epigenetic Mutations in Myelodysplastic Syndrome Stem Cells Ohio State University Comprehensive Cancer fellow 04/19/2016 - 04/19/2018 $47,268
James Mulloy, PhD Instructive Role of MLL Fusion Proteins in Lineage Determination and Leukemogenesis National Institutes of Health (The University of Chicago) R01 CA215504 04/01/2017 - 03/31/2022 $354,278
James Mulloy, PhD Molecular and Cellular Mechanisms of Chronic Myelomonocytic Leukemia (CMML) National Institutes of Health (University of Wisconsin-Madison) R01 CA152108 03/01/2017 - 02/28/2019 $39,000
Qing Richard Lu, PhD Targeting Tumor-Initiating Cells in Primary and Recurrent Medulloblastoma University of Cincinnati Lu, Qing, UC 07/01/2016 - 06/30/2017 $25,000
Robert A Coover, PhD Aberrant Purinergic Signaling in Neurofibromatosis Type 1 The Ohio State University Research Fnd Coover, Robert, OSU 10/01/2016 - 09/30/2018 $47,844
Punam Malik, MD The Phase I/II Pilot Study on Gene Transfer Therapy for Sickle Cell Disease National Institutes of Health (Social & Scientific Systems, Inc.) HHSN26800005 10/01/2016 - 05/31/2018 $1,849,839
Matthew Flick, PhD Thrombin-dependent Mechanisms of Pancreatic Ductal Adenocarcinoma Disease National Institutes of Health R01 CA211098 06/19/2017 - 05/31/2022 $431,067
Qing Richard Lu, PhD Identification of Clinically Targetable Pathways for the Treatment of Diffuse Intrinsic Pontine Glioma and High-grade Glioma through Chemical Genetic Screens University of Cincinnati (Mayfield Education and Research Foundation) Lu, Qing, merf 11/01/2016 - 10/31/2017 $50,000
Yi Zheng, PhD Activated Protein C Peptides for Radio-mitigation National Institutes of Health (P2D Bioscience) R43 AI127065 04/14/2017 - 03/31/2018 $69,078
Katelyn Melgar Novel Mechanisms and Therapeutic Strategies of Refractory Leukemia National Institutes of Health F31 CA217140 05/01/2017 - 04/30/2020 $36,256
Ashley E Cochran, PhD Environmental Carcinogenesis and Mutagenesis Training Grant National Institutes of Health (University of Cincinnati) T32 ES007250 12/01/2016 - 11/30/2018 $28,672
Dao Pan, PhD Gaucher Disease:Treatment of Neurodegenerative Disease National Institutes of Health R01 NS086134 06/01/2016 - 05/31/2018 $414,457
Timothy M Chlon, PhD Modeling Tissue-specific Effects of Fanconi Anemia using Human iPSC American Society of Hematology 2016ASHSCHOLAR 07/01/2016 - 06/30/2018 $50,000
Total Annual Grant Award Dollars $15,508,116

Annual Industry Award Dollars

Investigator Industry Sponsor Amount
Matthew Flick, PhD Fibriant, B.V. $76,488
Total Annual Industry Award Dollars $76,488