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Gastroenterology, Hepatology and Nutrition
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2017 Research Annual Report
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Gastroenterology, Hepatology and Nutrition
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Selected Publications
Top 25 Publications from FY17 Based on Impact Factor
Kugathasan S; Denson LA; Walters TD; Kim MO; Marigorta UM; Schirmer M; Mondal K; Liu C; Griffiths A; Noe JD.
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study.
The Lancet
. 2017; 389:1710-1718.
Camp JG; Sekine K; Gerber T; Loeffler-Wirth H; Binder H; Gac M; Kanton S; Kageyama J; Damm G; Seehofer D.
Multilineage communication regulates human liver bud development from pluripotency.
Nature
. 2017; 546:533-538.
Turpin W; Espin-Garcia O; Xu W; Silverberg MS; Kevans D; Smith MI; Guttman DS; Griffiths A; Panaccione R; Otley A.
Association of host genome with intestinal microbial composition in a large healthy cohort..
Nature Genetics
. 2016; 48:1413-1417.
Rosen MJ; Karns R; Vallance JE; Bezold R; Waddell A; Collins MH; Haberman Y; Minar P; Baldassano RN; Hyams JS.
Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients.
Gastroenterology
. 2017; 152:1345- 1357.e7.
Dellon ES; Katzka DA; Collins MH; Hamdani M; Gupta SK; Hirano I; MP-101-06 Investigators.
Budesonide Oral Suspension Improves Symptomatic, Endoscopic, and Histologic Parameters Compared With Placebo in Patients With Eosinophilic Esophagitis.
Gastroenterology
. 2017; 152:776-786.e5.
Brant SR; Okou DT; Simpson CL; Cutler DJ; Haritunians T; Bradfield JP; Chopra P; Prince J; Begum F; Kumar A.
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.
Gastroenterology
. 2017; 152:206-217.e2.
Schwimmer JB; Lavine JE; Wilson LA; Neuschwander-Tetri BA; Xanthakos SA; Kohli R; Barlow SE; Vos MB; Karpen SJ; Molleston JP.
In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores.
Gastroenterology
. 2016; 151:1141- 1154.e9.
Denson LA; Klein C.
Granulocyte-Macrophage Colony Stimulating Factor Bioactivity and Mucosal Homeostasis in Crohn's Disease: A Role for Genetic Variation.
Gastroenterology
. 2016; 151:593-596.
Vos MB; Kaar JL; Welsh JA; Van Horn LV; Feig DI; Anderson CAM; Patel MJ; Cruz Munos J; Krebs NF; Xanthakos SA.
Added Sugars and Cardiovascular Disease Risk in Children: A Scientific Statement From the American Heart Association..
Circulation
. 2017; 135:e1017-e1034.
Inge TH; Jenkins TM; Xanthakos SA; Dixon JB; Daniels SR; Zeller MH; Helmrath MA.
Long-term outcomes of bariatric surgery in adolescents with severe obesity (FABS-5+): a prospective follow-up analysis.
Lancet Diabetes and Endocrinology
. 2017; 5:165-173.
Morris DW; Stucke EM; Martin LJ; Abonia JP; Mukkada VA; Putnam PE; Rothenberg ME; Fulkerson PC.
Eosinophil progenitor levels are increased in patients with active pediatric eosinophilic esophagitis.
Journal of Allergy and Clinical Immunology
. 2016; 138:915-918.e5.
Wang KS; Tiao G; Bass LM; Hertel PM; Mogul D; Kerkar N; Clifton M; Azen C; Bull L; Rosenthal P.
Analysis of Surgical Interruption of the Enterohepatic Circulation as a Treatment for Pediatric Cholestasis.
Hepatology
. 2017; 65:1645-1654.
Lages CS; Simmons J; Maddox A; Jones K; Karns R; Sheridan R; Shanmukhappa SK; Mohanty S; Kofron M; Russo P.
The Dendritic Cell-T Helper 17-Macrophage Axis Controls Cholangiocyte Injury and Disease Progression in Murine and Human Biliary Atresia.
Hepatology
. 2017; 65:174-188.
Verkade HJ; Bezerra JA; Davenport M; Schreiber RA; Mieli-Vergani G; Hulscher JB; Sokol RJ; Kelly DA; Ure B; Whitington PF.
Biliary atresia and other cholestatic childhood diseases: Advances and future challenges.
Journal of Hepatology
. 2016; 65:631-642.
Leung DH; Heltshe SL; Borowitz D; Gelfond D; Kloster M; Heubi JE; Stalvey M; Ramsey BW; Stecenko A; Schechter M.
Effects of Diagnosis by Newborn Screening for Cystic Fibrosis on Weight and Length in the First Year of Life.
JAMA Pediatrics
. 2017; 171:546-554.
Newton KP; Hou J; Crimmins NA; Lavine JE; Barlow SE; Xanthakos SA; Africa J; Behling C; Donithan M; Clark JM.
Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease.
JAMA Pediatrics
. 2016; 170:e161971.
Mishra R; Chesi A; Cousminer DL; Hawa MI; Bradfield JP; Hodge KM; Guy VC; Hakonarson H; Mauricio D; Schloot NC.
Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes.
BMC Medicine
. 2017; 15:88.
Dellon ES; Collins MH; Bonis PA; Leung J; Capocelli KE; Dohil R; Falk GW; Furuta GT; Menard-Katcher C; Gupta SK.
Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders.
Clinical Gastroenterology and Hepatology
. 2016; 14:1842-1844.
Trout AT; Dillman JR; Xanthakos S; Kohli R; Sprague G; Serai S; Mahley AD; Podberesky DJ.
Prospective Assessment of Correlation between US Acoustic Radiation Force Impulse and MR Elastography in a Pediatric Population: Dispersion of US Shear-Wave Speed Measurement Matters.
Radiology
. 2016; 281:544-552.
Harrison SA; Marri SR; Chalasani N; Kohli R; Aronstein W; Thompson GA; Irish W; Miles MV; Xanthakos SA; Lawitz E.
Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis.
Alimentary Pharmacology and Therapeutics
. 2016; 44:1183-1198.
Nelson JE; Handa P; Aouizerat B; Wilson L; Vemulakonda LA; Yeh MM; Kowdley KV; Abrams SH; Himes R; Krisnamurthy R.
Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms.
Alimentary Pharmacology and Therapeutics
. 2016; 44:1253-1264.
Moshkovits I; Reichman H; Karo-Atar D; Rozenberg P; Zigmond E; Haberman Y; Ben Baruch-Morgenstern N; Lampinen M; Carlson M; Itan M.
A key requirement for CD300f in innate immune responses of eosinophils in colitis.
Mucosal immunology
. 2017; 10:172-183.
Asai A; Aihara E; Watson C; Mourya R; Mizuochi T; Shivakumar P; Phelan K; Mayhew C; Helmrath M; Takebe T.
Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells.
Development (Cambridge)
. 2017; 144:dev.142794.
Koike H; Zhang RR; Ueno Y; Sekine K; Zheng YW; Takebe T; Taniguchi H.
Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism.
Development (Cambridge)
. 2017; 144:1018-1024.
Hsu EK; Bucuvalas J.
The Trouble With Exceptional Exceptions.
American Journal of Transplantation
. 2016; 16:3073-3074.