Robbins Lab

Qi, L; Zang, H; Wu, W; Nagarkatti, P; Nagarkatti, M; Liu, Q; Robbins, J; Wang, X; Cui, T. CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes. Journal of Molecular and Cellular Cardiology. 2020; 145:59-73.

Xu, N; Gulick, J; Osinska, H; Yu, Y; McLendon, PM; Shay-Winkler, K; Robbins, J; Yutzey, KE. Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination. Circulation Research. 2020; 126:907-922.

Baker, RS; Zafar, F; Kimura, N; Knilans, T; Osinska, H; Robbins, J; Taylor, M; Morales, DL S. In Vivo Remodeling of an Extracellular Matrix Cardiac Patch in an Ovine Model. ASAIO Journal. 2019; 65:744-752.

Robbins, J; James, J. Myocardium and Development. In: Wernovsky G; Anderson RH; Krishna K; Mussato KA; Redington A; Tweddell JS; Tretter J, Ed. Anderson's Pediatric Cardiology. Philadelphia, PA: Elsevier; 2019.

Zheng, D; Su, Z; Zhang, Y; Ni, R; Fan, G; Robbins, J; Song, L; Li, J; Peng, T. Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity. Archives of Toxicology. 2019; 93:1051-1065.

Meng, Q; Bhandary, B; Bhuiyan, MS; James, J; Osinska, H; Valiente-Alandi, I; Shay-Winkler, K; Gulick, J; Molkentin, JD; Blaxall, BC; et al. Myofibroblast-Specific TGFβ Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy. Circulation Research. 2018; 123:1285-1297.

Lowey, S; Bretton, V; Joel, PB; Trybus, KM; Gulick, J; Robbins, J; Kalganov, A; Cornachione, AS; Rassier, DE. Hypertrophic cardiomyopathy R403Q mutation in rabbit β-myosin reduces contractile function at the molecular and myofibrillar levels. Proceedings of the National Academy of Sciences of the United States of America. 2018; 115:11238-11243.

Abdullah, CS; Alam, S; Aishwarya, R; Miriyala, S; Panchatcharam, M; Bhuiyan, MA N; Peretik, JM; Orr, AW; James, J; Osinska, H; et al. Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics. Journal of the American Heart Association. 2018; 7.

Bhandary, B; Meng, Q; James, J; Osinska, H; Gulick, J; Valiente-Alandi, I; Sargent, MA; Bhuiyan, S; Blaxall, BC; Molkentin, JD; et al. Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF -β Signaling. Journal of the American Heart Association. 2018; 7.

Alam, S; Abdullah, CS; Aishwarya, R; Miriyala, S; Panchatcharam, M; Peretik, JM; Orr, AW; James, J; Robbins, J; Bhuiyan, MS. Aberrant Mitochondrial Fission Is Maladaptive in Desmin Mutation-Induced Cardiac Proteotoxicity. Journal of the American Heart Association. 2018; 7.

Singh, SR; Robbins, J. Desmin and Cardiac Disease: An Unfolding Story. Circulation Research. 2018; 122:1324-1326.

Singh, SR; Zech, AT L; Geertz, B; Reischmann-Duesener, S; Osinska, H; Prondzynski, M; Kraemer, E; Meng, Q; Redwood, C; van der Velden, J; et al. Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice. Circulation: Heart Failure. 2017; 10.

Meng, Q; Bhandary, B; Osinska, H; James, J; Xu, N; Shay-Winkler, K; Gulick, J; Willis, MS; Lander, C; Robbins, J. MMI-0100 Inhibits Cardiac Fibrosis in a Mouse Model Overexpressing Cardiac Myosin Binding Protein C. Journal of the American Heart Association. 2017; 6.

McLendon, PM; Davis, G; Gulick, J; Singh, SR; Xu, N; Salomonis, N; Molkentin, JD; Robbins, J. An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels. Circulation Research. 2017; 121:604-616.

Pleasant, L; Ma, Q; Devarajan, M; Parameswaran, P; Drake, K; Siroky, B; Shay-Winkler, K; Robbins, J; Devarajan, P. Increased susceptibility to structural acute kidney injury in a mouse model of presymptomatic cardiomyopathy. American Journal of Physiology - Renal Physiology. 2017; 313:F699-F705.

Xu, N; Bitan, G; Schrader, T; Klaerner, F; Osinska, H; Robbins, J. Inhibition of Mutant αB Crystallin-Induced Protein Aggregation by a Molecular Tweezer. Journal of the American Heart Association. 2017; 6.

DeSena, HC; Landis, BJ; Moore, RA; Spar, DS; Whiteside, W; Blaxall, BC. Future Diagnostic Strategies-Pediatric. Cardioskeletal Myopathies in Children and Young Adults. 2017.

Wilmot, I; Jefferies, JL; Ryan, TD. Dilated Cardiomyopathy and Cardioskeletal Involvement. Cardioskeletal Myopathies in Children and Young Adults. 2017.

Towbin, JA. Left Ventricular Noncompaction Cardiomyopathy. Cardioskeletal Myopathies in Children and Young Adults. 2017.

Robbins, J. Diseases of the Cytoskeleton. Cardioskeletal Myopathies in Children and Young Adults. : Elsevier; Elsevier; 2017.

Khuchua, Z; Towbin, JA. Cardio-Skeletal Muscle Disease Associated With Syndromes. Cardioskeletal Myopathies in Children and Young Adults. 2017.

Mathew, J; Redington, A. Cardioskeletal Myopathies in Congenital Heart Diseases. Cardioskeletal Myopathies in Children and Young Adults. 2017.

Jefferies, JL; Blaxall, BC; Robbins, J; Towbin, JA. Cardioskeletal Myopathies in Children and Young Adults.