The Center for Acute Care Nephrology (CACN) was established as a resource for children and adults whose health conditions put them at risk of acute kidney injury (AKI).  AKI refers to an abrupt loss of kidney function due to other diseases or their treatment. Once AKI occurs, it may not be able to be reversed and may lead to chronic kidney damage.  Some of the most common reasons that AKI may occur in children and adults are:

  • Heart Disease
  • Major surgeries including cardiac surgery
  • Chemotherapy
  • Sepsis:  a severe, whole body infection
  • Nephrotoxic medications

The CACN is the only center in the world that works with all areas of critical care to focus on AKI.  This collaboration with other divisions within Cincinnati Children’s  enables physicians and researchers to closely monitor how children and adults with kidney problems are responding to treatment, make rapid adjustments where needed, and give the patient standardized care for the best possible outcomes. Additionally, CACN faculty and staff are able to coordinate with our collaborating divisions to provide structured targeted follow-up care for both AKI, and resultant CKD.  In these follow-up settings, patients and families are provided with printed educational materials pertaining to their child’s diagnosis.

Glossary of Terms Associated with Acute Kidney Injury

  • Acute Kidney Injury:  The abrupt loss of kidney function
  • Nephrotoxic medications: Medications that may lead to AKI
  • Chronic Kidney Disease: Decreased kidney function that is not recoverable
  • Nephrology: The study of kidney related disease