Study for Adults With Temporomandibular Joint Disorder (TMJD)

Why are we doing this research?

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn more about the reasons for and impact of TMJD, a common facial pain condition.

Who can participate?

Adults 18 to 50 years old who have facial pain or TMJD may be eligible to participate.


  • Adult Studies
  • Bones - Joints - Muscles

What will happen in the study?

This study involves two visits: a screening visit and a testing visit. Each visit will last about 3 hours.

Here are some of the things that will happen during the study:

You will:

  • Complete a health questionnaire
  • Have a clinical exam, including a facial/dental exam and answer questions about your medical history
  • Complete questionnaires to help us better understand your personality, how you cope with problems, and how you feel about yourself
  • Have short assessments about how your body feels pain and your sensitivity to different stimuli such as hot and cold sensations, pressure, etc.
  • Be asked to wear a watch-like device on your wrist for 7 days that measures activity and sleep
  • Complete a daily diary about your sleep and symptoms you might feel during the day
  • Submit a urine sample, if you are female
  • Submit blood samples
  • Complete a weekly health survey for 3 months

You will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.

What are the good things that can happen from this research?

Being in this study may not help you right now. However, when we complete this study, we hope that we will know more about pain, inflammation, stress and sleep. This may help other people with TMJD and other chronic pain conditions in the future.

What are the bad things that can happen from this research?

Possible risks and discomforts will be discussed with you, if you are interested in learning more about this study.

Will you/your child be paid to be in this research study?

Participants may receive up to $140 for time and effort.


Contact Us.The Study Coordinator
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.Christopher D. King, PhD
Cincinnati Children’s Hospital Medical Center