Asthma Study for Children and Teens 6 to 17 Years Old

Why are we doing this research?

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn if an asthma medication, given along with standard asthma care, helps to make children less likely to have asthma attacks.

Who can participate?

Children and teens 6 to 17 years old with asthma who:

  • Have had 2 or more asthma attacks in the last year


  • Are taking a daily inhaled medication


  • Asthma
  • Chest and Lungs - Respiratory Tract

What will happen in the study?

This study includes 15 study visits to Cincinnati Children’s over a 12 month period, up to 3 visits when your child has a cold, and visits when he/she has an asthma flare up.

Here are some of the things that will happen in this study:

We will ask you questions about your child’s health.

Your child will:

  • Complete breathing tests
  • Have an allergy skin test
  • Submit blood, urine and nasal samples
  • Be randomized (like flipping a coin) to either receive the study drug mepolizumab or a placebo (inactive) shot

The study team will ask you to call if your child starts to show signs of a cold and bring them in for a “cold” visit. The purpose of these visits is to collect samples soon after his/her cold starts. They will also ask you to bring them in if your child has an asthma attack after these visits.

Parents or guardians interested in having their child participate will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.

What are the good things that can happen from this research?

Your child may directly benefit by receiving asthma care from an asthma specialist. You will receive information about your child’s breathing and allergen tests, as well as information about taking care of your child’s asthma.

Your child’s asthma may or may not improve while in this study, but he/she will be followed closely during the study.

Overall, the information we learn from this study may lead to study doctors having a better understanding of whether mepolizumab helps children to have fewer asthma attacks.

What are the bad things that can happen from this research?

Possible risks and discomforts will be discussed with parents or guardians interested in learning more about the study.

Will you/your child be paid to be in this research study?

Families will receive up to $1,125 over approximately 1 year (15 visits) for time and travel.


Contact Us.ICAC Study Team
Asthma Research Center
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.Gurjit Khurana Hershey, MD
Asthma Research Center
Cincinnati Children’s Hospital Medical Center