Clinical Trials / Research Studies

Clinical Trials / Research Studies

COVID-19 Investigational Nasal Vaccine Study for Adults Who Have NOT Had COVID-19 Vaccines or COVID-19 Infection

Why are we doing this research?

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn about a new investigational nasal COVID-19 vaccine that may offer protection from COVID-19.

Who can participate?

Adults 18 to 75 years old who are generally healthy and:

  • Interested in participating in a COVID nasal vaccine study and
  • Have not had a COVID-19 infection or COVID-19 vaccine

 

Conditions

  • Healthy Adults
  • COVID-19/Coronavirus
  • Vaccines

What will happen in the study?

The study includes 9 planned study visits and 2 phone calls over 1 year. You may be requested to come into our study center for visits outside of your scheduled visits if you have any symptoms of COVID-19. Here are some of the things that will happen in this study.

You will:

  • Complete a symptom diary to record any symptoms which occur prior to trial vaccination, on the day of trial vaccination, 30 minutes after trial vaccination and for 28 days after receiving the trial vaccine.
  • Have a physical exam and tell us about your medical history
  • Submit blood and urine samples
  • If female, have a pregnancy test
  • Have nasal swabs
  • Receive one low dose of the study vaccine or one high dose of the study vaccine (given into the nose as a spray into each nostril)

You will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.

What are the good things that can happen from this research?

You may or may not personally benefit from your participation in this trial. However, by taking part, you will help to provide new scientific information that will contribute to the development of COVID-19 vaccines.

What are the bad things that can happen from this research?

As with any vaccine, you may have side effects. Expected side effects common from intranasal vaccines include runny nose/nasal congestion, sore throat and cough. You may have discomfort from having blood draws and nasal swabs. We will discuss possible risks and discomforts with you prior to the start of the study.

Will you/your child be paid to be in this research study?

Participants will receive up to $975 for time and effort to complete the study.

Contact

Contact Us.

To see if you qualify, go to redcap.link/COVID-19Vaccine
or contact:
Gamble Program for Clinical Studies
513-636-7699
gambleprogram@cchmc.org
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.

Paul Spearman, MD
Infectious Diseases
Cincinnati Children’s Hospital Medical Center