Clinical Trials / Research Studies

Clinical Trials / Research Studies

Study for Healthy Adults 18 to 49 Years Old

Why are we doing this research?

Cincinnati Children’s is doing a research study, sometimes known as a clinical trial or clinical study, to learn if an experimental Nipah vaccine is safe and causes our body to make antibodies to protect against Nipah infection. Nipah and Hendra virus may cause severe disease. The vaccine will not cause you to get the Nipah virus.

Who can participate?

Healthy adults 18 to 49 years old may be eligible to participate.


  • Healthy Adults
  • Vaccines

What will happen in the study?

This study involves receipt of 2 to 3 vaccine doses and 7 clinic visits during a 7 month period. Here are some of the things that will happen in this study:

You will:

  • Be asked about your health and any medicines you take
  • Have a physical exam including temperature, blood pressure, pulse, height and weight measurements
  • Have a blood draw at most visits
  • If female and able to have children, have pregnancy testing
  • Receive the HeV-sG-V study vaccine or placebo vaccine at 2 or 3 visits (decided by chance – like flipping a coin) in your left or right upper arm.
  • Be willing to go to Hoxworth to donate plasma for antibody collection
  • Complete a memory aid for 7 days after you receive the vaccine to record your temperature and any symptoms

You will be given a consent form and study handout that gives details of the study. A member of the study staff will review the consent form with you and answer your questions.

What are the good things that can happen from this research?

Being in this study may not help you right now. When we finish this study, we hope that we will know if the study vaccine may help provide protection against infection with the Nipah Virus.

What are the bad things that can happen from this research?

Possible risks and discomforts will be discussed with those interested in learning more about the study.

Will you/your child be paid to be in this research study?

Participants may receive up to $1000 to $1050 for time and effort.


Contact Us.To see if you qualify, go to
or contact:
Gamble Program for Clinical Studies
Infectious Diseases
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.Robert Frenck, MD
Infectious Diseases
Cincinnati Children’s Hospital Medical Center