Study for Healthy Adults 19 to 64 Years Old

Why are we doing this research?

Cincinnati Children’s is doing a research study, sometimes known as a clinical trial or clinical study, to learn how safe and effective experimental bird flu vaccines are when given with seasonal flu vaccine. Participants will not get bird flu from this vaccine.

Who can participate?

Healthy adults 19 to 64 years old may be eligible to participate.


  • Healthy Adults
  • Adult Studies
  • Vaccines

What will happen in the study?

This study involves up to 3 vaccinations and up to 9 clinic visits during a 13-month period. Here are some of the things that will happen in this study:

You will:

  • Be asked about your health and any medicines you take
  • Have a physical exam including temperature, blood pressure, height and weight measurements
  • Have a blood draw at most visits
  • If female, have pregnancy testing (if you are able to have children)
  • Receive either 2 study vaccines and the seasonal flu vaccine or just the seasonal flu vaccine (decided by chance – like flipping a coin)
  • Complete a memory aid for 7 days after you receive each of the vaccine doses to record your temperature and any symptoms

You will be given a consent form and study handout that gives details of the study. A member of the study staff will review the consent form with you and answer all of your questions.

What are the good things that can happen from this research?

Being in this study may not help you right now. When we finish this study, we hope that we will know if the study vaccine and 2017-2018 seasonal flu vaccine work better if they are given together or apart to protect you from the bird flu virus.

What are the bad things that can happen from this research?

Possible risks and discomforts will be discussed those interested in learning more about the study.

Will you/your child be paid to be in this research study?

Participants may receive up to $800 for time and effort.


Contact Us.Gamble Program for Clinical Studies
Infectious Diseases
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.Paul Spearman, MD
Infectious Diseases
Cincinnati Children’s Hospital Medical Center