Clinical Trials / Research Studies
Clinical Trials / Research Studies

Study for Healthy Girls 9 to 13 and Boys 9 to 14

Why are we doing this research?

Cincinnati Children’s is conducting a research study to learn more about how puberty affects bone density and bone marrow composition.

Who can participate?

Healthy girls 9 t0 13 years old and boys 9 to 14 may be eligible to participate.


  • Healthy Infants, Children and Adolescent Studies

What will happen in the study?

This study includes 2 study visits over 1 year. Here is what will happen in this study:

At each visit your child will:

  • Have their height and weight obtained
  • Have a physical exam to check puberty stage
  • Answer questions about their health history, diet, exercise, mood and quality of life
  • Have a DXA scan of their whole body, hip and spine in an open machine to measure bone density and body composition
  • Have a pQCT scan of their leg in an open machine to measure bone mineral density
  • Have an MRI scan of their knee to measure bone marrow composition

Parents interested in having their child participate will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.

What are the good things that can happen from this research?

You or your child will not have a direct medical benefit. However, the information we learn from this study may help us to know more about the effects of puberty on bone health.

What are the bad things that can happen from this research?

Your child will be exposed to a small amount of additional radiation, as part of this study. The amount is less than the normal background exposure your child receives over 5 days.

Will you/your child be paid to be in this research study?

Families will receive up to $300 for two study visits over one year.


Contact Us.Go to
or contact:
Leah Tyzinski

Study Doctor

Contact Us.Heidi Kalkwarf, PhD
Gastroenterology, Hepatology & Nutrition
Cincinnati Children’s Hospital Medical Center