Study for Teen Girls With Juvenile Idiopathic Arthritis

Why are we doing this research?

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to learn more about how teen girls with idiopathic arthritis experience pain and other frequent symptoms. The study involves an MRI scan.

Who can participate?

Teen girls 13 to 17 years old who have been diagnosed with idiopathic arthritis and have bodily pain on a regular basis who:

  • Are right-handed
  • Do not have any other significant medical or psychiatric diagnoses
  • Do not have braces or other metal in their body
  • Are not afraid to be in a small place such as the MRI scanner

Conditions

  • Arthritis
  • Rheumatology

What will happen in the study?

This study includes 3 study visits totaling 2 to 3 hours to complete the study. Here are some of the things that will happen in this study:

Participants will:

  • In the first visit:
    • Answer questions about their medication, thoughts, emotions and sensations including pain
    • Practice the tasks including hearing tasks that will be completed while in the MRI scanner
    • Complete a pregnancy test
  • In the second visit:
    • Have photos taken of their brain in the MRI scanner while being asked to complete tasks and games
    • Have brief pressure pain stimuli on their thumbnail and be asked about the level of pain
  • In the third visit:
    • Be reminded about and will practice the tasks and games from the previous visits and will be asked to complete them in the MRI scan again

Parents and teen participants will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.

What are the good things that can happen from this research?

Participants will not receive a direct benefit from completing this study. However, the information we learn from this study may help us to learn more about juvenile idiopathic arthritis.

What are the bad things that can happen from this research?

Possible risks and discomforts will be discussed with parents/guardians and teens interested in learning more about the study.

Will you/your child be paid to be in this research study?

Participants will receive up to $170 for three study visits.

Contact

Contact Us.Michael Payne
513-803-0288
painresearchcenter@cchmc.org
Pain Research Center
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.Marina Lopez-Sola, PhD
Pain Research Center
Anesthesia
Cincinnati Children’s Hospital Medical Center