Migraine Headache Study For Children and Teens 12 to 17

Why are we doing this research?

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to compare brain activity and structure in children and teens who have migraines with that of children and teens who are healthy.

Who can participate?

Children and teens 12 to 17 years old without braces who have been diagnosed with migraine headaches, but who have no other chronic pain may be eligible to participate.


  • Headaches - Migraines

What will happen in the study?

This study involves a screening visit and an MRI visit. A detailed list of procedures will be provided to those interested in knowing more about this study. Here are some of the procedures:

Participants will be asked to:

  • Complete a migraine and health form
  • Fill out questionnaires to help us understand your personality, how you cope with problems, and how you feel about yourself
  • Wear a watch-like device on your wrist before the MRI visit
  • Complete a daily diary about sleep and daily symptoms
  • Have an MRI scan on the second visit which will last about 1 hour
  • Complete quarterly (every 3 months) assessments after the MRI scan

Parents interested in having their child or teen participate will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered. 

What are the good things that can happen from this research?

Participants will not receive a direct medical benefit from taking part in this study. However, when we complete the study, we hope that we will know more about migraines and sleep. This information could help other children and teens with migraines and other chronic pain conditions in the future.

What are the bad things that can happen from this research?

Possible risks and discomforts will be discussed with parents or guardians interested in learning more about the study.

Will you/your child be paid to be in this research study?

Participants may receive up to $70 for two visits and follow-up surveys.


Contact Us.Study Coordinator
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039

Study Doctor

Contact Us.Christopher D. King, PhD
Cincinnati Children’s Hospital Medical Center