Clinical Trials / Research Studies

Clinical Trials / Research Studies

The TEAM Study: A Study for Adults Whose Mothers Were Enrolled in the Diabetes in Pregnancy Program between 1978 & 1995

Why are we doing this research?

From 1978 to 1995, an important study called the Diabetes in Pregnancy Program closely followed nearly 500 pregnant women who were diagnosed with diabetes before pregnancy. Information was collected about how they managed their diabetes throughout their pregnancy.

We, as researchers at Cincinnati Children’s, are conducting a research study to learn more about how a pregnant woman’s health may influence the health of her children as they reach adulthood. We are wanting to enroll the adult children of women who participated in the Diabetes in Pregnancy Program between 1978 and 1995, in this follow-up study.

Our study is called “Level and Timing of Diabetic Hyperglycemia in utero: the Transgenerational Effect on Adult Morbidity (TEAM Study)” or the TEAM Study for short. The TEAM Study is currently being conducted here at Cincinnati Children’s.

Because everyone eligible for the TEAM Study is the child of a woman who participated in the Diabetes in Pregnancy Program, this is a unique opportunity to look at a mother’s health information during pregnancy and match it to her adult child’s current health.

Who can participate?

You would qualify for this study if your mother was followed in the Diabetes in Pregnancy Program between 1978 and 1995 while she was pregnant with you. This program closely followed nearly 500 pregnant women who were diagnosed with diabetes before pregnancy. Information was collected about how the pregnant women managed their diabetes throughout their pregnancy.

Many of our participants so far didn’t know that their mother was part of the Diabetes in Pregnancy Program, so you may be eligible without realizing it! If your mother had diabetes while she was pregnant with you, and you were born in the Cincinnati area between 1978 and 1995 you may be eligible for the TEAM Study. The best way to find out if you are eligible is to contact us and we will be happy to check and let you know if you are eligible for this study.

We hope to enroll and complete a study visit with at least 250 people eligible for our study.

Conditions

  • Adult Studies
  • Diabetes
  • Healthy Adults

What will happen in the study?

If eligible and once enrolled in this study, you will be asked to come to Cincinnati Children’s for one in-person visit that could last up to eight hours. You will be asked to not eat or drink anything (other than water) for the 9 hours before your study visit.

During the study visit, you will be asked to:

  • Fill out a questionnaire about your personal health, diet and family history
  • Have your height, weight, waist and blood pressure measured
  • Have your blood drawn
  • Provide urine samples
  • Complete a series of critical thinking tests
  • Have your body scanned using an open scanner
  • Take part in heart tests to look at how blood flows through your body
  • Have your feet examined

Additionally, after the study visit, we would like you to complete two “diet recall” phone calls about what you ate the day before and have you complete an online questionnaire about what types of foods you have eaten in the month after the visit.

We are interested in talking with you even if you cannot come to Cincinnati for the study visit in the near future.

What are the good things that can happen from this research?

While there is no direct benefit to you from being in this study, we hope it will help improve the health of children of women with diabetes in the future. The goal is to try to find ways to help mothers watch their health while pregnant so that their babies are healthy and stay healthy as children into adulthood.

What are the bad things that can happen from this research?

This is a “minimal risk” study, which means that the risks of participating are the same as ordinary daily life or routine doctor visits. We will discuss possible risks and discomforts in more detail with those interested in learning more about the study.

Will you/your child be paid to be in this research study?

As a TEAM Study participant, you will receive up to $410 for your time and effort.

Contact

Contact Us.Study Research Coordinator
theTEAMStudy@cchmc.org
513-517-1045

Study Doctor

Contact Us.Jane Khoury, PhD
Biostatistics and Epidemiology
Cincinnati Children’s