Why are we doing this research?
Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to better understand the beneficial effects of yoga to reduce anxiety, depression and stress, and improve overall well-being in teen girls who have eating disorders (anorexia nervosa).
Who can participate?
Teen girls 13 to 18 years old who have been diagnosed with an eating disorder (anorexia nervosa) may be eligible to participate.
What will happen in the study?
Teen girls will be randomized into 1 of 2 study groups (selection similar to flipping a coin). One of the study groups includes 24 weeks of yoga classes, and the second group is a non-yoga group.
Teens in both groups will come to Cincinnati Children’s 3 times over the next 6 months and be monitored closely. Here are some of things that will happen in this study:
Teen girls will:
- Have their height and blinded weight (meaning that they will not be told their weight) taken
- Have blood pressure and other measurements taken
- Complete questionnaires to assess anxiety, depression and mood changes
- Provide information about daily meals
- Answer questions about health history and exercise habits
- Have fMRI (functional magnetic resonance imaging) scans – 1 at the beginning of the study and 1 at the end – to take pictures of their brain while shown photos of food items
- Have DXA (dual energy x-ray absorptiometry) scans – 1 at the beginning of the study and 1 at the end – to measure their bone density and body composition
- Have pQCT (peripheral quantitative computed tomography) scans – 1 at the beginning of the study and 1 at the end – to measure their bone mineral density
Parents interested in having their daughter participate will be given a consent form that thoroughly explains all of the details of the study. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.
What are the good things that can happen from this research?
If your daughter is in the yoga group, we hope that it will help her to feel better and/or reduce stress and improve her overall mood. If your daughter is not in the yoga group, she will continue to be closely followed by her eating disorder doctor and other clinicians at Cincinnati Children’s and information from the study may be used to help with her clinical care.
Overall, when we finish the research, we expect that we will know more about the addition of yoga practice to clinical care to improve your daughter’s overall health.
What are the bad things that can happen from this research?
Possible risks and discomforts will be discussed with parents or guardians and teens interested in learning more about the study.