The Cytogenetics Laboratory at Cincinnati Children's Hospital Medical Center offers a wide range of FISH panels. 

Cytogenetics FISH Panels

FISH PANEL FISH PROBES INCLUDED IN PANEL

All Hyperdiploid Panel

  • CEP 4
  • CEP 10
  • CEP 17

All Risk Stratification Panel

  • CEP 4
  • t(12;21)
  • CEP 10
  • MLL
  • CEP 17
  • BCR/ABL

AML Panel

  • t(8;21)
  • Inv 16 / t(16;16)
  • MLL

APL Panel

  • t(15;17)
  • RARA

 

Burkitt Lymphoma

  • t(8;14)
  • C-MYC

 

CLL Panel

  • 13q14.3 / 13q34 /  CEP 12
  • 11q22.3 / 17p13 (p53)

 

Eosinophilia Panel

  • 4q12 PDGFR alpha
  • 16q22 CBFB
  • 5q32 PDGFR beta
  • 8p11 FGFR1

Fanconi Anemia Panel

  • 1p36 / 1q25
  • 3q27 (BCL6)
  • Mono 7 / del 7q

Large Cell NHL Panel

  • ALK (2p23.2)
  • t(11;14)
  • t(14;18)
  • BCL6 (3q27)
  • 17p13 (p53)

Multiple Myeloma Panel −
Isolation of CD138+ cells

 

  • t(11;14)
  • 17p13 (p53)
  • 13q14.3
  • t(4;14)
  • 13q34
  • t(14;16)

Myeloid Disorders Panel

  • Mono 5 / del 5q
  • 20q- 
  • Mono 7 / del 7q
  • Trisomy 8

Myeloproliferative Disorder (MPD) Panel

  • 4q12 PDGFR alpha
  • 22q11.2 (BCR) / 9q34 (ABL)
  • 5q32 PDGFR beta
  • 8p11 FGFR1

NHL Combination Panel

  • 13q14.3 / 13q34 / CEP 12
  • t(11:14)
  • 11q22.3 / 17p13 (p53)
  • t(14;18) [IgH/BCL2]
  • 2p23[ALK]
  • 18q21 [MALT1]
  • BCL6 (3q27)

Small B-Cell NHL Panel

  • CLL Panel
  • MALT1
  • t(11;14)
  • t(14;18)

SDS (Shwachman-Diamond Syndrome) Panel

  • Del / mono 7
  • Trisomy 8
  • 20q-