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High Res

Eileen C. King, PhD

Associate Professor, UC Department of Pediatrics

Phone: 513-803-1819

Fax: 513-636-1254

Email: eileen.king@cchmc.org

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Specialties

Clinical Trials, Statistical Process Control, Data Management, Nonparametric Regression using Linear Smoothers.

Biography

Dr. King has provided biostatistical leadership in the design, analysis, and interpretation of results from animal and human clinical research studies supporting drug discovery, early and late stage drug development, commercialization, and market support. She provided statistical expertise and oversight for the development, review, and defense of 10 New Drug Application submissions in the areas of gastrointestinal, cardiac, bone diseases and female sexual health. She is currently leading the growing Data Management Center to assure appropriate data management processes for data collection, data cleaning and validation, and data finalization, documentation and archival are used which lead to high quality data that can be shared with the research community at large.

Dr. King is active in the American Statistical Association and is currently chair of the Council of Sections Governing Board. She is an Associate Editor for the Journal of Statistical Education. Dr. King mentors junior faculty, staff and students in DBE and Gastroenterology and the Anderson Center. She is the primary instructor of “Statistical Principles for Clinical Research Studies” in the UC College of Pharmacy.

Education and Training

PhD: Texas A&M University, 1988.

MS: University of Wyoming, 1980.

BS: Regis College, 1976.

Publications

Crandall, W. V., Margolis, P. A., Kappelman, M. D., King, E. C., Pratt, J. M., Boyle, B. M.,Colletti, R. B. Improved Outcomes in a Quality Improvement Collaborative for Pediatric Inflammatory Bowel Disease. Pediatrics. doi: 10.1542/peds.2011-1700. 2012.

Presicce P, Orsborn K, King E, Pratt J, Fichtenbaum CJ, et al. Frequency of Circulating Regulatory T Cells Increases during Chronic HIV Infection and Is Largely Controlled by Highly Active Antiretroviral Therapy. PLoS ONE 6(12): e28118.doi:10.1371/journal.pone.0028118. 2011.

Seid M, D’Amico EJ, Varni JW, Munafo JK, Britto MT, Kercsmar CM, Drotar D, King EC, Darbie L. The In Vivo Adherence Intervention For at Risk Adolescents with Asthma: Report of a Randomized Pilot Trial. Journal of Pediatric Psychology. doi:10.1093/jpepsy/jsr107. 2011.

Setchell K, Brown N, Zhao X, Lindley S, Heubi J, King E, Messina J. Soy isoflavone phase II metabolism differs between rodents and humans: implications for the effect on breast cancer risk. Am J Clin Nutr. 94:1284-94. 2011.

Debrosse, C. W., Franciosi, J. P., King, E. C., Buckmeier Butz, B. K., Greenberg, A. B., Collins, M. H., Abonia, J. P., Assa'ad, A., Putnam, P. E., & Rothenberg, M. E. Long-term outcomes in pediatric-onset esophageal eosinophilia. J Allergy Clin Immunol, 2011.

DeBrosse CW, Collins MH, Butz BK Allen CL, King EC, Assa’ad AH, Abonia JP, Putnam PE, Rothenberg ME, Franciosi JP. Identification, epidemiology and chronicity of pediatric esophageal eosinophilia, 1982-1999. Journal of Allergy and Clinical Immunology. 126 (1), pp. 112-119. 2010.

Corey AE, Agnew,JR, King EC, Parekh NJ, Powell JH, Thompson GA. Effect of Mild and Moderate Hepatic Impairment on Azimilide Pharmacokinetics Following Single Dose Oral Administration. Journal of Pharmaceutical Sciences, 93 (5), pp. 1279-1286. 2004.

Sorof JM, Cargo P, Graepel J, Humphrey D, King E, Rolf C, Cunningham R. b-Blocker/thiazide combination for treatment of hypertensive children: a randomized double-blind, placebo-controlled trial. Pediatric Nephrology. 17, pp. 345-350. 2002.

Chen KS, Bharaj SS, and King EC. Induction and relief of nasal congestion in ferrets infected with influenza virus. International Journal of Experimental Pathology, 76, pp. 55-64. 1995.

King EC, Hart JD, and Wehrly TE. Testing the Equality of Two Regression Curves Using Linear Smoothers. Statistics and Probability Letters, 12, pp. 239-247. 1991.

Grants

Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Disease. Biostatistician. National Institutes of Health. August 2007 – May 2012.

Open Source Science: Transforming Chronic Illness Care. Statistician. National Institutes of Health. September 2009 – August 2014.

Cincinnati Center for Clinical and Translational Science and Training. Biostatistician. National Institutes of Health. March 2009 – February 2014.

Building Modular Pediatric Chronic Disease Registries for QI and CE Research. Biostatistician. National Institutes of Health. September 2010 – September 2013.

The Pedi IBD Network for Res & Improvement. Biostatistician. PIBDNet Trailblazer Collaborative. October 2010 – June 2012.