A photo of James Cnota.

Director, Fetal Cardiology


Board Certified

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My Biography & Research


While pediatric cardiology involves aspects of acute care and technical expertise, I chose this specialty because my relationship with patients and families is often long-lasting. A fetal cardiologist starts a relationship at the time of prenatal diagnosis, helps a family through the stress of the diagnosis and early cardiac care, and then watches as the child grows up. This relationship with patients and families is very fulfilling for me.

As a pediatric cardiologist, I treat children with congenital heart defects. I am also involved with echocardiography, and I direct the Fetal Heart Program at Cincinnati Children’s. My philosophy of care is to be compassionate and honest, even when the news is difficult. This approach is how I hope my own family would be treated.

The Fetal Heart Program can make a detailed diagnosis that informs prenatal counseling and care. In partnership with the obstetrician, we support mothers and families in a comprehensive manner to achieve the best possible delivery outcome for mom and cardiac outcome for the baby.

In my research, my colleagues and I are trying to improve outcomes in children with heart disease through multicenter research collaborations. We are also seeking to understand how genetics contributes to the cause of congenital heart disease and how genetics contributes to differences in outcomes between patients with congenital heart disease. Another goal is to understand why babies with congenital heart disease are often born too small and too early.

In my free time, I enjoy relaxing with my family, running and travel.

Clinical Interests

Congenital heart disease; echocardiography; fetal cardiology; Cardiology Consult Service; General Cardiology Outpatient Clinic; Interstage Program

Research Interests

Multicenter clinical studies; perinatal outcomes in congenital heart disease


Fetal Care, Single Ventricular Interstage, Cardiac MRI, Heart, Cardiology, Heart

Science Blog

My Locations

My Education

BS: Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, 1991.

MD: Tulane University School of Medicine, New Orleans, Louisiana, 1995.

Residency: University of Arizona Health Sciences Center, Tucson, Arizona, 1998.

Fellowship: Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2001.

MS: Clinical Epidemiology and Health Services Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina, 2005.

My Publications

Behavior and quality of life at 6 years for children with hypoplastic left heart syndrome. Goldberg, CS; Hu, C; Brosig, C; Gaynor, JW; Mahle, WT; Miller, T; Mussatto, KA; Sananes, R; Uzark, K; Trachtenberg, F; et al. Pediatrics. 2019; 144:e20191010-e20191010.

Challenges With Left Ventricular Functional Parameters: The Pediatric Heart Network Normal Echocardiogram Database. Frommelt, PC; Trachtenberg, FL; Altmann, K; Cohen, MS; Colan, SD; Frommelt, MA; Johnson, TR; Kovalchin, JP; Nutting, A; Pearson, GD; et al. Journal of the American Society of Echocardiography. 2019; 32:1331-1338.e1.

Gestational Age, Birth Weight, and Outcomes Six Years After the Norwood Procedure. Miller, TA; Ghanayem, NS; Newburger, JW; McCrindle, BW; Hu, C; DeWitt, AG; Cnota, JF; Tractenberg, FL; Pemberton, VL; Wolf, MJ; et al. Pediatrics. 2019; 143:e20182577-e20182577.

Tricuspid atresia with restrictive foramen ovale: A rare combination with implications on fetal growth. Tseng, SY; Alsaied, T; Barnard, K; Hahn, E; Divanovic, AA; Cnota, JF. Echocardiography: a journal of cardiovascular ultrasound and allied techniques. 2019; 36:800-802.

Prenatal heart block screening in mothers with SSA/SSB autoantibodies: Targeted screening protocol is a cost-effective strategy. Evers, PD; Alsaied, T; Anderson, JB; Cnota, JF; Divanovic, AA. Congenital Heart Disease. 2019; 14:221-229.

Prevalence of Noonan spectrum disorders in a pediatric population with valvar pulmonary stenosis. Anderson, K; Cnota, J; James, J; Miller, EM; Parrott, A; Pilipenko, V; Weaver, KN; Shikany, A. Congenital Heart Disease. 2019; 14:264-273.

Impact of Initial Shunt Type on Echocardiographic Indices in Children After Single Right Ventricle Palliations The SVR Trial at 6 Years. Frommelt, PC; Hu, C; Trachtenberg, F; Baffa, JM; Boruta, RJ; Chowdhury, S; Cnota, JF; Dragulescu, A; Levine, JC; Lu, J; et al. Circulation: Cardiovascular Imaging. 2019; 12.

Health-Related Quality of Life in Children and Young Adults with Marfan Syndrome. Handisides, JC; Hollenbeck-Pringle, D; Uzark, K; Trachtenberg, FL; Pemberton, VL; Atz, TW; Bradley, TJ; Cappella, E; De Nobele, S; Groh, GK-T; et al. The Journal of Pediatrics. 2019; 204:250-255.e1.

Cardiovascular Disease in the Young Council's Science and Clinical Education Lifelong Learning Committee: Year in Review. Reddy, S; Marino, BS; Baker-Smith, CM; Beaton, A; Krawczeski, CD; Miyake, CY; Cnota, JF; Glatz, AC; Feingold, B; Romano, JC; et al. Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease. 2018; 7.

Effect of fetal hemodynamics on growth in fetuses with single ventricle or transposition of the great arteries. Alsaied, T; Tseng, S; King, E; Hahn, E; Divanovic, A; Habli, M; Cnota, J. Ultrasound in Obstetrics and Gynecology. 2018; 52:479-487.