A photo of Eileen King.

Eileen C. King, PhD


  • Professor, UC Department of Pediatrics

About

Biography

I’m involved in multi-institutional and multi-disciplinary clinical research studies and provide biostatistical leadership in the design, analysis, interpretation and reporting of research results. My areas of research include statistics, data management and data coordination for clinical research networks. I am a statistician with expertise in clinical trial design and work with industry and regulatory agencies to create a clinical research development program for drugs, biologics and devices.

Before joining Cincinnati Children's, I worked in the pharmaceutical industry and was involved in the drug development process. I understand the importance of planning a drug development program and having the infrastructure with experts in their field to support the program and maximize success. I think industry and academia must work in close partnership to develop new treatments for pediatric and rare diseases. With my background in both industry and academia, I am committed to developing and fostering these collaborations.

Our Data Management and Coordinating Centers (DMCC) strengthen the ability of research networks to understand the complex pathways characterizing the etiology, diagnosis and management of diseases and the network's ability to assess clinical trial readiness. Our DMCCs provide the infrastructure to address a network's data management and analysis needs, with strong leadership, governance, decision-making, resource management and communication. The DMCC enables research centers to collaborate effectively, apply reproducible research principles and state-of-the-art methods, promote and measure progress toward trial readiness and enhance the impact of findings using advanced dissemination and implementation strategies.

Our lab is the data coordinating center for the Rare Disease Clinical Research Network and the coordinating center for the Bench to Bassinet program. These National Institutes of Health (NIH) awards are two of the top three awards ever awarded to Cincinnati Children's researchers.

I am a fellow of the American Statistical Association (ASA) and served on the board of directors for the ASA, the top international association for statisticians. I served as an associate editor for the Journal of Statistical Education and as a statistical reviewer for other scientific journals. I have been a statistician for more than 30 years and began working at Cincinnati Children's in 2009.

Publications

Design and rationale for the supermarket and web-based intervention targeting nutrition (SuperWIN) for cardiovascular risk reduction trial. Couch, SC; Helsley, RN; Siegel, FU; Saelens, BE; Magazine, M; Eckman, MH; Summer, S; Fenchel, M; King, EC; Bhatt, DL; et al. American Heart Journal. 2022; 248:21-34.

Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Shoda, T; Collins, MH; Rochman, M; Wen, T; Caldwell, JM; Mack, LE; Osswald, GA; Besse, JA; Haberman, Y; Aceves, SS; et al. Gastroenterology. 2022; 162:1635-1649.

Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms After Dilation in Adults With Eosinophilic Esophagitis. Safroneeva, E; Pan, Z; King, E; Martin, LJ; Collins, MH; Yang, GY; Capocelli, KE; Arva, NC; Abonia, JP; Atkins, D; et al. Clinical Gastroenterology and Hepatology. 2022; 20:766-775.e4.

Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort. Hirano, I; Collins, MH; King, E; Sun, Q; Chehade, M; Abonia, JP; Bonis, PA; Capocelli, KE; Dellon, ES; Falk, GW; et al. American Journal of Gastroenterology. 2022; 117:413-423.

Outcomes of Multiple Runs of Extracorporeal Membrane Oxygenation: An analysis of the Extracorporeal Life Support Registry. Cooper, DS; Thiagarajan, R; Henry, BM; Byrnes, JW; Misfeldt, A; Frischer, J; King, E; Gao, Z; Rycus, P; Marino, BS. Journal of Intensive Care Medicine. 2022; 37:195-201.

Characteristics of paediatric weight management in the United States: Associations with program retention and BMI outcomes in the paediatric obesity weight evaluation registry (POWER). Tucker, JM; Stratbucker, W; King, EC; Cuda, S; Negrete, S; Sweeney, B; Kumar, S; Borzutzky, C; Binns, HJ; Kirk, S. Pediatric obesity. 2022; 17.

Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Shoda, T; Wen, T; Caldwell, JM; Ben-Baruch Morgenstern, N; Osswald, GA; Rochman, M; Mack, LE; Felton, JM; Abonia, JP; Arva, NC; et al. Gastroenterology. 2022; 162:439-453.

Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis. Hiremath, G; Sun, L; Correa, H; Acra, S; Collins, MH; Bonis, P; Arva, NC; Capocelli, KE; Falk, GW; King, E; et al. American Journal of Gastroenterology. 2022; 117:272-279.

Elevated blood pressure in youth in pediatric weight management programs in the Pediatric Obesity Weight Evaluation Registry (POWER). Binns, HJ; Joseph, M; Ariza, AJ; Cuda, SE; Skinner, AC; Xu, H; Tucker, JM; Hampl, SE; Santos, M; Mayo, S; et al. Journal of Clinical Hypertension. 2022; 24:122-130.

Patient Retention in Pediatric Weight Management Programs in the United States: Analyses of Data from the Pediatrics Obesity Weight Evaluation Registry. Skinner, AC; Xu, H; Christison, A; Neshteruk, C; Cuda, S; Santos, M; Yee, JK; Thomas, L; King, E; Kirk, S. Childhood Obesity. 2022; 18:31-40.

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