A photo of Eileen King.

Professor, UC Department of Pediatrics

513-803-1819

513-636-1254

Biography & Affiliation

Biography

I’m involved in multi-institutional and multi-disciplinary clinical research studies and provide biostatistical leadership in the design, analysis, interpretation and reporting of research results. My areas of research include statistics, data management and data coordination for clinical research networks. I am a statistician with expertise in clinical trial design and work with industry and regulatory agencies to create a clinical research development program for drugs, biologics and devices.

Before joining Cincinnati Children's, I worked in the pharmaceutical industry and was involved in the drug development process. I understand the importance of planning a drug development program and having the infrastructure with experts in their field to support the program and maximize success. I think industry and academia must work in close partnership to develop new treatments for pediatric and rare diseases. With my background in both industry and academia, I am committed to developing and fostering these collaborations.

Our Data Management and Coordinating Centers (DMCC) strengthen the ability of research networks to understand the complex pathways characterizing the etiology, diagnosis and management of diseases and the network's ability to assess clinical trial readiness. Our DMCCs provide the infrastructure to address a network's data management and analysis needs, with strong leadership, governance, decision-making, resource management and communication. The DMCC enables research centers to collaborate effectively, apply reproducible research principles and state-of-the-art methods, promote and measure progress toward trial readiness and enhance the impact of findings using advanced dissemination and implementation strategies.

Our lab is the data coordinating center for the Rare Disease Clinical Research Network and the coordinating center for the Bench to Bassinet program. These National Institutes of Health (NIH) awards are two of the top three awards ever awarded to Cincinnati Children's researchers.

I am a fellow of the American Statistical Association (ASA) and served on the board of directors for the ASA, the top international association for statisticians. I served as an associate editor for the Journal of Statistical Education and as a statistical reviewer for other scientific journals. I have been a statistician for more than 30 years and began working at Cincinnati Children's in 2009.

Research Interests

Clinical trials; data coordinating centers; data management; cardiac; pediatric obesity; gastrointestinal; health learning networks

Academic Affiliation

Professor, UC Department of Pediatrics

Research Divisions

Biostatistics and Epidemiology



Blog Posts

Education

BS: Regis College, Weston, MA, 1976.

MS: University of Wyoming, Laramie, WY, 1980.

PhD: Texas A&M University, College Station, TX, 1988.

Publications

Acute Kidney Injury, Fluid Overload, and Renal Replacement Therapy Differ by Underlying Diagnosis in Neonatal Extracorporeal Support and Impact Mortality Disparately. Murphy, HJ; Gien, J; Sahay, R; King, E; Selewski, DT; Bridges, BC; Cooper, DS; Fleming, GM; Paden, ML; Zappitelli, M; et al. Blood Purification. 2021; 1-10.

Trends in prescribing anti-obesity pharmacotherapy for paediatric weight management: Data from the POWER Work Group. Borzutzky, C; King, E; Fox, CK; Stratbucker, W; Tucker, J; Yee, JK; Kumar, S; Cuda, S; Sweeney, B; Kirk, S; et al. Pediatric obesity. 2021; 16.

Outcomes of Multiple Runs of Extracorporeal Membrane Oxygenation: An analysis of the Extracorporeal Life Support Registry. Cooper, DS; Thiagarajan, R; Henry, BM; Byrnes, JW; Misfeldt, A; Frischer, J; King, E; Gao, Z; Rycus, P; Marino, BS. Journal of Intensive Care Medicine. 2020.

Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy: a multicenter retrospective cohort study. Gorga, SM; Sahay, RD; Askenazi, DJ; Bridges, BC; Cooper, DS; Paden, ML; Zappitelli, M; Gist, KM; Gien, J; Basu, RK; et al. Pediatric Nephrology. 2020; 35:871-882.

Belatacept-based immunosuppression with simultaneous calcineurin inhibitor avoidance and early corticosteroid withdrawal: A prospective, randomized multicenter trial. Woodle, ES; Kaufman, DB; Shields, AR; Leone, J; Matas, A; Wiseman, A; West-Thielke, P; Sa, T; King, EC; Alloway, RR; et al. American Journal of Transplantation. 2020; 20:1039-1055.

Elucidation of de novo small insertion/deletion biology with parent-of-origin phasing. Seiden, AH; Richter, F; Patel, N; Rodriguez, OL; Deikus, G; Shah, H; Smith, M; Roberts, A; King, EC; Sebra, RP; et al. Human Mutation. 2020; 41:800-806.

Acute Kidney Injury, Fluid Overload, and Outcomes in Children Supported With Extracorporeal Membrane Oxygenation for a Respiratory Indication. Mallory, PP; Selewski, DT; Askenazi, DJ; Cooper, DS; Fleming, GM; Paden, ML; Murphy, L; Sahay, R; King, E; Zappitelli, M; et al. ASAIO Journal. 2020; 66:319-326.

Reply to Letter to the Editor by Frank Nice. Nommsen-Rivers, L; King, E; Wagner, E; Riddle, S; Ward, L; Thompson, A. Journal of Human Lactation. 2020; 36.

Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Aceves, S; Collins, MH; Rothenberg, ME; Furuta, GT; Gonsalves, N; Abonia, JP; Almonte, S; Andrews, R; Arrington, A; Arva, N; et al. Journal of Allergy and Clinical Immunology. 2020; 145:28-37.

Implementing a Novel Quality Improvement-Based Approach to Data Quality Monitoring and Enhancement in a Multipurpose Clinical Registry. Pratt, J; Jeffers, D; King, EC; Kappelman, MD; Collins, J; Margolis, P; Baron, H; Bass, JA; Bassett, MD; Beasley, GL; et al. eGEMs. 2019; 7.