Ming Tan, PhD

Assistant Professor, UC Department of Pediatrics

Phone 513-636-0510

Fax 513-636-7655

Email ming.tan@cchmc.org

Noroviruses; human caliciviruses; viral gastroenteritis
PhD: University of Münster, Münster, Germany, 1997.

Chen YT, Tan M, Xia M, Hao N, Zhang XJ, Huang PW, Jiang X, Li XM, Rao ZH. Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity selected by human histo-blood group antigen receptors. PLoS Pathogens. 2011.

Tan M, Jiang X. Norovirus-host interaction: multi-selections by the human histo-blood group antigens. Trends in Microbiology. 2011.

Tan M, Fang PA, Xia M, Chachiyo T, Jiang W, Jiang X. Terminal modifications of norovirus P domain resulted in a new type of subviral particles, the small P particles. Virology. 2011 Feb 20;410(2):345-52.

Tan M, Huang P, Xia M, Fang PA, Zhong W, McNeal M, Wei C, Jiang W, Jiang X. Norovirus P particle, a novel platform for vaccine development and antibody production. J Virol. 2011 Jan;85(2):753-64.

Yang Y, Xia M, Tan M, Huang PW, Zhong WM, Pang XL, Lee BE, Meller J, Wang T, and Jiang X. Genetic and phenotypic characterization of GII-4 noroviruses isolated in 1987-2008. Journal of Virology. 2010 Sep; 84(18): 9595-607.

Tan M, and Jiang X. Norovirus gastroenteritis, carbohydrate receptors and animal models. PLoS Pathogen. 2010 Aug 26;6(8).

Tan M, Xia M, Chen Y, Bu W, Hegde RS, Meller J, Li X and Jiang X. Conservation of Receptor Binding Interfaces, Evidence of Human HBGA selection in Norovirus Evolution . PLoS One. 2009; 4(4): e5058. 

Tan M, Fang P, Chachiyo T, Xia M, Huang P, Fang Z, Jiang W and Jiang X. Noroviral P Particle: Structure, Function and Applications in Virus-Host Interaction . Virology. 2008; 382 (1):115-123. 

Jin M, Xie HP, Duan ZJ, Liu N, Zhang Q, Wu BS, Li HY, Cheng WX, Yang SH, Yu JM, Xu ZQ, Cui SX, Zhu L, Tan M, Jiang X and Fang ZY.  Emergence of the GII4/2006b Variant and Recombinant Noroviruses in China . Journal of Medical Virology. 2008; 80(11):1997-2004. 

Tan M, Xia M, Cao S, Huang P, Farkas T, Meller J, Hegde RS, Li X, Rao Z and Jiang X.  Elucidation of strain-specific interaction of a GII-4 norovirus with HBGA receptors by site-directed mutagenesis study . Virology. 2008; 379(2):324-334.

Noroviral P particle, a multifunctional platform for vaccine development. Principal Investigator. National Institutes of Health. June 2011 - May 2013.

Norwalk-like viruses and their receptors. Co-Investigator. National Institutes of Health. Sep 2010 - Apr 2015.

Novel vaccine against norovirus. Co-Principal Investigator. National Institutes of Health. May 2010 -  Apr 2015.