Reproductive Biology
Research in these areas include:
- The basis of genetic or drug-induced congenital malformations, attempting to prevent birth defects in some of the 150,000 afflicted babies born each year.
- The processes of gametogenesis, egg maturation, embryo implantation, and gonad development, cellular processes that are prime targets for new contraceptive methods and infertility treatments. Other research includes the etiology of germ cell tumors, which are one of the most common tumors arising in children.
Faculty
Sudhansu K. Dey, MD, Professor, Director, Division of Reproductive Sciences
Molecular and genetic basis of embryo-uterine interactions during early pregnancy [Visit the Dey Lab]
Louis Muglia, MD, PhD, Professor
Genetic and developmental mechanisms controlling the timing of birth and risk of preterm birth; molecular genetic analysis of the behavioral and neuroendocrine responses to stress. [Visit the Muglia Lab]
Satoshi Namekawa, PhD, Assistant Professor
The long-term goal of our research is to understand the mechanisms and evolution of epigenetic events during mammalian germ cell development [Visit Reproductive Sciences]
Yuya Ogawa, PhD
Molecular mechanisms of long noncoding RNA-mediated epigenetic gene regulation during mammalian development; X-chromosome inactivation using ex vivo differentiation system with mouse ES cells. [Visit Reproductive Sciences]
Steven Potter, PhD, Professor
Studies of homeobox genes that control mammalian development using gene targeting and transgenic mice [Visit the Potter Lab]
Susan Waltz, PhD, Associate Professor
Molecular analysis of growth factors and receptor tyrosine kinases in tumorigenesis, organ function, and cellular trauma [Visit the Waltz Lab]
Michael Williams, PhD, Research Associate Professor
Interaction of stress-induced hormones and drugs of abuse on adult learning and memory abilities; physiological responses to later stressors; behavioral and physiological consequences of drug reexposure. [Visit the Michael Williams Lab]
Christopher Wylie, PhD, Professor
(1) Control of the cytoskeleton, control of cell migration and control of early cell lineage specification, in vertebrate embryos (2) Control of gonad formation, primordial germ cell migration, oocyte maturation and egg formation [Visit the Wylie-Heasman Lab]
Contact Us
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
