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The broad goals of this research is to understand the cellular, molecular and genetic mechanisms that drive immunologically-mediated disorders.
Dysregulated immune responses are of central importance to the pathogenesis and expression of a wide spectrum of disease (HIV, asthma, coronary artery disease, arthritis, cystic fibrosis, cancers) that cause an immense burden of morbidity and mortality in the US and the world at large.
Artem Barski, PhD, Assistant ProfessorEpigenomics of immunological memory [Visit Allergy and Immunology]
Jay Degen, PhD, Professor The role of hemostatic factors and coupled signaling systems in development, inflammatory response, vessel wall disease and tumor biology [Visit Experimental Hematology and Cancer Biology]
Lee Grimes, PhD, ProfessorHematopoiesis, molecular biology, and molecular oncology including mouse modeling of hematopoiesis, myelopoiesis and leukemia. [Visit the Grimes Lab]
John Harley, MD, PhD, ProfessorWe work to bring the new technologies of genomics to clinical care. We do this for the institution as a service and for our own work in autoimmunity. At the moment we are evaluating the microbiome in blood for systemic lupus erythematosus. [Visit Rheumatology]
Gurjit Hershey, MD, PhD, Professor Genetics and the pathogenesis of atopic disorders [Visit Asthma Research]
David Hildeman, PhD, ProfessorMolecular biology of antigen-specific T cells, including mechanisms involved in cell signaling, apoptosis, and sex-based differences in autoimmunity and the T cell response to viral infections [Visit Immunobiology]
Kenneth Kaufman, PhD, ProfessorUtilization of next generation DNA sequencing data to identify variants that cause disease. We are particularly interested in autoimmune diseases such as systemic lupus erythematosus. [Visit CAGE]
Tim Le Cras, PhD, Associate ProfessorChronic lung diseases: Asthma, Bronchopulmonary dysplasia, Pulmonary fibrosis, Pulmonary hypertension [Visit the Le Cras Lab]
Takahisa Nakamura, PhD, Assistant ProfessorFunctional analysis of small RNAs and their binding proteins in integrative organ crosstalk in metabolic diseases. [Visit Endocrinology]
Marc Rothenberg, MD, PhD, ProfessorEosinophil biology, chemokine receptor signaling pathways [Visit the Rothenberg Lab]
Stephen N. Waggoner, PhD, Assistant ProfessorWe are interested in host and viral factors that control disease pathogenesis by regulating development of long-lived immunological memory, generation of potent immune effector cells, and functional repression of immune function during chronic infection. [Visit the Waggoner Lab]
Jeffrey A. Whitsett, MD, Professor Organ morphogenesis, gene regulation, cell differentiation, respiratory disease [Visit the Whitsett Lab]
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